関正史

Seki Masafumi

研究分野 (1件)：血液、腫瘍内科学

競争的資金等の研究課題 (1件)：

2017 - 2018 先端的ゲノム・エピゲノム解析を駆使した小児造血器腫瘍における難治化機序の解明

論文 (109件)：

Joana Carrelha, Stefania Mazzi, Axel Winroth, Michael Hagemann-Jensen, Christoph Ziegenhain, Kari Högstrand, Masafumi Seki, Margs S Brennan, Madeleine Lehander, Bishan Wu, et al. Alternative platelet differentiation pathways initiated by nonhierarchically related hematopoietic stem cells. Nature immunology. 2024. 25. 6. 1007-1019
Kentaro Watanabe, Shunsuke Kimura, Masafumi Seki, Tomoya Isobe, Yasuo Kubota, Masahiro Sekiguchi, Aiko Sato-Otsubo, Mitsuteru Hiwatari, Motohiro Kato, Akira Oka, et al. Identification of the ultrahigh-risk subgroup in neuroblastoma cases through DNA methylation analysis and its treatment exploiting cancer metabolism. Oncogene. 2022. 41. 46. 4994-5007
樋渡光輝, 関正史, 松野良介, 吉田健一, 長澤武, 佐藤亜以子, 山本将平, 加藤元博, 渡邉健太郎, 関口昌央, et al. 神経芽腫における新規TENM 3-ALK融合遺伝子の解析(Novel ALK fusion in neuroblastoma involving TENM3, a conserved family of transmembrane protein). 日本癌学会総会記事. 2022. 81回. J-3016
Tomoya Isobe, Masatoshi Takagi, Aiko Sato-Otsubo, Akira Nishimura, Genta Nagae, Chika Yamagishi, Moe Tamura, Yosuke Tanaka, Shuhei Asada, Reina Takeda, et al. Multi-omics analysis defines highly refractory RAS burdened immature subgroup of infant acute lymphoblastic leukemia. Nature communications. 2022. 13. 1. 4501-4501
Ko Kudo, Yasuo Kubota, Tsutomu Toki, Rika Kanezaki, Akie Kobayashi, Tomohiko Sato, Takuya Kamio, Shinya Sasaki, Norio Shiba, Daisuke Tomizawa, et al. Childhood acute myeloid leukemia with 5q deletion and HNRNPH1-MLLT10 fusion: the first case report. Blood advances. 2022. 6. 10. 3162-3166

MISC (111件)：

村田翔, 副島尭史, 鈴木征吾, 樋渡光輝, 関正史, 三谷友一, 日高もえ, 佐竹和代, 野口隼, 湯坐有希, et al. 入院治療中の小児がん患者の身体活動量と家族機能の関連. 日本小児血液・がん学会雑誌. 2019. 56. 4. 383-383
久保田泰央, 関正史, 関口昌央, 吉田美沙, 吉田健一, 樋渡光輝, 宮野悟, 岡明, 林泰秀, 田中祐吉, et al. ターゲットキャプチャー法による小児胚細胞腫瘍の変異解析. 日本小児科学会雑誌. 2019. 123. 2. 263-263
Kentaro Watanabe, Shunsuke Kimura, Masafumi Seki, Tomoya Isobe, Tomoko Kawai, Mitsuteru Hiwatari, Kenichi Yoshida, Yuichi Shiraishi, Kenichi Chiba, Kenichiro Hata, et al. Inhibition of phosphoglycerate dehydrogenase reduces neuroblastoma growth and arginine deiminase expands its application. CANCER SCIENCE. 2018. 109. 249-249
Yuji Yamada, Shota Kato, Ryota Shirai, Tomoo Osumi, Chikako Kiyotani, Toshihiko Watanabe, Tomoro Hishiki, Masahiro Sekiguchi, Masafumi Seki, Junko Takita, et al. Sibling Cases of Pleuropulmonary Blastoma with Compound Heterozygous DICER1 Mutations. PEDIATRIC BLOOD & CANCER. 2018. 65. S74-S75
Shunsuke Kimura, Masafumi Seki, Tomoko Kawai, Kenichi Yoshida, Tomoya Isobe, Hiroo Ueno, Yusuke Shiozawa, Hiromichi Suzuki, Yuichi Shiraishi, Kentaro Ohki, et al. DNA Methylation-Based Characterization of T-cell Acute Lymphoblastic Leukemia Well Correlated with Genetic Features, Prognosis and Differentiation Stages. PEDIATRIC BLOOD & CANCER. 2018. 65. S21-S22

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