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Watanabe Hirotaka

所属機関・部署：
職名：特任講師

研究分野 (1件)：神経科学一般

研究キーワード (6件)：シナプス , 人工多能性幹細胞 , ゲノム編集 , モデル動物 , 神経生物学 , アルツハイマー病

競争的資金等の研究課題 (2件)：

論文 (36件)：

Hirotaka Watanabe, Rei Murakami, Hideyuki Okano. Amyloid β (Aβ) ELISA of Human iPSC-Derived Neuronal Cultures. Methods in molecular biology (Clifton, N.J.). 2021
Sho Yoshimatsu, Mayutaka Nakajima, Aozora Iguchi, Tsukasa Sanosaka, Tsukika Sato, Mari Nakamura, Ryusuke Nakajima, Eri Arai, Mitsuru Ishikawa, Kent Imaizumi, et al. Non-viral Induction of Transgene-free iPSCs from Somatic Fibroblasts of Multiple Mammalian Species. Stem cell reports. 2021. 16. 4. 754-770
Tsukika Sato, Kent Imaizumi, Hirotaka Watanabe, Mitsuru Ishikawa, Hideyuki Okano. Generation of region-specific and high-purity neurons from human feeder-free iPSCs. Neuroscience letters. 2021. 746. 135676-135676
Hirotaka Watanabe, Kent Imaizumi, Tetsuo Cai, Zhi Zhou, Taisuke Tomita, Hideyuki Okano. Flexible and accurate substrate processing with distinct presenilin/γ-secretases in human cortical neurons. eNeuro. 2021
Nicolas Leventoux, Satoru Morimoto, Kent Imaizumi, Yuta Sato, Shinichi Takahashi, Kyoko Mashima, Mitsuru Ishikawa, Iki Sonn, Takahiro Kondo, Hirotaka Watanabe, et al. Human Astrocytes Model Derived from Induced Pluripotent Stem Cells. Cells. 2020. 9. 12

MISC (3件)：

講演・口頭発表等 (7件)：

ヒト神経細胞でのプレセニリン/γ-セクレターゼ生理機能を解析する幹細胞ツールの開発
(第42回日本神経科学大会 2019)
Presenilin and Alzheimer’s.
(Blue Ribbon Panel Meeting 2018)
The roles of γ-secretase and its substrates on the pathogenesis of neurodegenerative dementia.
(National Institute of Genetics- the 1801st Biological Symposium 2015)
Generation and analysis of mouse models to examine the roles of γ-secretase and its substrates on the pathogenesis of neurodegenerative dementia.
(第35回日本神経科学会 2013)
Generation and analysis of mouse models to examine the roles of γ-secretase and its substrates on the pathogenesis of neurodegenerative dementia.
(The Gordon Research Conference: Neurobiology of Brain Disorders 2012)

学位 (1件)：

経歴 (4件)：

所属学会 (3件)：

日本認知症学会 , 北米神経科学学会 , 日本神経科学会

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