2021 - 2024 Structure-guided engineering of a biodegradable plastic synthase for tailor-made polymer production
論文 (16件)：
Pei Fang Sim, Min Fey Chek, Nhung Thi Hong Nguyen, Tamako Nishimura, Takehiko Inaba, Toshio Hakoshima, Shiro Suetsugu. The SH3 binding site in front of the WH1 domain contributes to the membrane binding of the BAR domain protein endophilin A2. Journal of biochemistry. 2023
Wan Nurul Izzati Wan Mohamad Noor, Nhung Thi Hong Nguyen, Theng Ho Cheong, Min Fey Chek, Toshio Hakoshima, Takehiko Inaba, Kyoko Hanawa-Suetsugu, Tamako Nishimura, Shiro Suetsugu. Small GTPase Cdc42, WASP, and scaffold proteins for higher-order assembly of the F-BAR domain protein. Science advances. 2023. 9. 17. eadf5143
Hua Tiang Tan, Min Fey Chek, Soon Zher Neoh, Shaik Ling Ang, Shosuke Yoshida, Toshio Hakoshima, Kumar Sudesh. Characterization of the polyhydroxyalkanoate (PHA) synthase from Ideonella sakaiensis, a bacterium that is capable of degrading and assimilating poly(ethylene terephthalate). POLYMER DEGRADATION AND STABILITY. 2022. 206
Hua Tiang Tan, Min Fey Chek, Yuki Miyahara, Sun-Yong Kim, Takeharu Tsuge, Toshio Hakoshima, Kumar Sudesh. Characterization of an (R)-specific enoyl-CoA hydratase from Streptomyces sp. strain CFMR 7: A metabolic tool for enhancing the production of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate). Journal of bioscience and bioengineering. 2022
Soon Zher Neoh, Min Fey Chek, Hua Tiang Tan, Javier A. Linares-Pastén, Ardra Nandakumar, Toshio Hakoshima, Kumar Sudesh. Polyhydroxyalkanoate synthase (PhaC): The key enzyme for biopolyester synthesis. Current Research in Biotechnology. 2022. 4. 87-101
Enzymatic Polymerization towards Green Polymer Chemistry. Chapter 7: Synthesis of Polyesters III: Acyltransferase as Catalyst
Springer Singapore 2019 ISBN:9789811338137
講演・口頭発表等 (9件)：
"Crystal structure of bioplastic-synthesizing PHA synthase (PhaC) revealing an unexpected open-closed heterodimer"
(the 47th International Congress on Science, Technology and Technology-based Innovation (STT47) 2021)
Crystal structure of PHA synthase and the unexpected open-closed heterodimer
(ISBP 2021 Webinar series 2021)
Structural and functional insight into the bioplastic-producing enzyme - PHA synthase
(27th FAOBMB & 44th MSBMB Conference 2019 2019)
Structural and functional insight into the bioplastic-producing enzyme - PHA synthase
(Young Scientist Program, IUBMB in conjunction with 27th FAOBMB & 44th MSBMB Conference 2019 2019)
Structural studies of the catalytic domain of PHA synthase from Chromobacterium sp. USM2
(The 10th International Conference of Modification, Degradation and Stabilization of Polymers (MoDeSt208) 2018)
