文献

J-GLOBAL ID：201802214009284063   整理番号：18A1418404

グルココルチコイド受容体発現はPBMC移植NOGhIL-4-TgマウスにおいてヒトB細胞生着と負の相関を示す

Expression of glucocorticoid receptor shows negative correlation with human B-cell engraftment in PBMC-transplanted NOGhIL-4-Tg mice

著者 (10件)： Seki Toshiro (Department of Internal Medicine, Division of Nephrology, Endocrinology and Metabolism, Tokai University School of Medicine) ,  Miyamoto Asuka (Department of Molecular Life Science, Division of Basic Medical Science, Tokai University School of Medicine) ,  Miyamoto Asuka (Department of Breast and Endocrine Surgery, Tokai University School of Medicine) ,  Ohshima Shino (Department of Molecular Life Science, Division of Basic Medical Science, Tokai University School of Medicine) ,  Ohno Yusuke (Department of Molecular Life Science, Division of Basic Medical Science, Tokai University School of Medicine) ,  Yasuda Atsushi (Department of Internal Medicine, Division of Nephrology, Endocrinology and Metabolism, Tokai University School of Medicine) ,  Tokuda Yutaka (Department of Breast and Endocrine Surgery, Tokai University School of Medicine) ,  Ando Kiyoshi (Department of Hematology and Oncology, Tokai University School of Medicine) ,  Kametani Yoshie (Department of Molecular Life Science, Division of Basic Medical Science, Tokai University School of Medicine) ,  Kametani Yoshie (Institute of Advanced Biosciences, Tokai University)
資料名： BioScience Trends  (BioScience Trends)
巻： 12  号： 3  ページ： 247-256(J-STAGE)  発行年： 2018年 
JST資料番号： L8367A  ISSN： 1881-7815  CODEN： BTIRCZ  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： 日本 (JPN)  言語： 英語 (EN)

抄録/ポイント： ヒト化マウス系は,in vivoでのヒト免疫応答を分析するた...

シソーラス用語： マウス ,...
準シソーラス用語： *末梢血単核細胞

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著者キーワード (4件)： ヒト化マウス ,  IL-4 ,  THサブセット ,  グルココルチコイド受容体

分類 (2件)： 免疫性疾患・アレルギー性疾患一般  (GD04010C) ,  基礎治療学  (GC03012A)

引用文献 (45件)：

• 1. Kametani Y, Miyamoto A, Seki T, Ito R, Habu S, Tokuda Y. The significance of humanized mouse models for the evaluation of the humoral immune response against cancer vaccines. Personalized Medicine Universe. 2018. Doi. org/10.1016/j.pmu.2018.04.002
• 2. Shultz LD, Lang PA, Christianson SW, Gott B, Lyons B, Umeda S, Leiter E, Hesselton R, Wagar EJ, Leif JH, Kollet O, Lapidot T, Greiner DL. NOD/LtSz-Rag1null mice: An immunodeficient and radioresistant model for engraftment of human hematolymphoid cells, HIV infection, and adoptive transfer of NOD mouse diabetogenic T cells. J Immunol. 2000; 164:2496-2507.
• 3. Ito M, Hiramatsu H, Kobayashi K, Suzue K, Kawahata M, Hioki K, Ueyama Y, Koyanagi Y, Sugamura K, Tsuji K, Heike T, Nakahata T. NOD/SCID/gamma_c^null mouse: An excellent recipient mouse model for engagement of human cells. Blood. 2002; 100:3175-3182.
• 4. Shultz L, Ishikawa F, Greiner D. Humanized mice in translational biomedical research. Nat Rev Immunol. 2007; 7:118-130.
• 5. Bouaziz J, Yanaba K, Tedder T. Regulatory B cells as inhibitors of immune responses and inflammation. Immunol Rev. 2008; 224:201-214.

タイトルに関連する用語 (10件)： グルココルチコイド受容体 ,  発現 ,  PBMC ,  移植 ,  TG ,  マウス ,  ヒト ,  B細胞 ,  生着 ,  相関