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J-GLOBAL ID：201802230938414342   整理番号：18A0350365

Gelsemium elegansの根からの5種の新しいコウミン型アルカロイド【Powered by NICT】

Five new koumine-type alkaloids from the roots of Gelsemium elegans

著者 (15件)： Zhang Wei (Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, People’s Republic of China) ,  Zhang Wei (Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, People’s Republic of China) ,  Zhang Sheng-Yuan (Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, People’s Republic of China) ,  Zhang Sheng-Yuan (Medical College, Jiaying University, Meizhou 514031, People’s Republic of China) ,  Wang Gui-Yang (Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, People’s Republic of China) ,  Li Ni-Ping (Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, People’s Republic of China) ,  Chen Min-Feng (Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, People’s Republic of China) ,  Gu Ji-Hong (Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, People’s Republic of China) ,  Zhang Dong-Mei (Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, People’s Republic of China) ,  Zhang Dong-Mei (Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, Guangzhou 510632, People’s Republic of China) ,  Wang Lei (Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, People’s Republic of China) ,  Wang Lei (Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, Guangzhou 510632, People’s Republic of China) ,  Ye Wen-Cai (Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, People’s Republic of China) ,  Ye Wen-Cai (Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, People’s Republic of China) ,  Ye Wen-Cai (Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, Guangzhou 510632, People’s Republic of China)
資料名： Fitoterapia  (Fitoterapia)
巻： 118  ページ： 112-117  発行年： 2017年 
JST資料番号： A1197A  ISSN： 0367-326X  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： オランダ (NLD)  言語： 英語 (EN)

抄録/ポイント： 五新しいコウミン型アルカロイド(1 5)と共に六種の既知のものはGelsemium elegansの根から単離した。絶対配置と共にそれらの構造をNMR分光法と電子円偏光二色性スペクトル解析に基づいて解明した。三種の腫瘍細胞系(649,HepG2およびHuH7)の生存性に及ぼす1 11化合物の阻害効果は,MTT分析により評価した。Copyright 2018 Elsevier B.V., Amsterdam. All rights reserved. Translated from English into Japanese by JST.【Powered by NICT】

シソーラス用語： *NMR【磁気共鳴】 ,  HepG2細胞 ,  スペクトル解析 ,  絶対配置
準シソーラス用語： *Gelsemium ,  生存性 ,  腫瘍細胞株 ,  電子円偏光二色性 , 【Automatic Indexing@JST】

著者キーワード (3件)： Gelsemium elegans ,  コウミン型アルカロイド ,  細胞毒性活性

分類 (2件)： 植物の生化学  (EH01050J) ,  アルカロイド  (CF10030D)

タイトルに関連する用語 (3件)： 根 ,  コウミン ,  アルカロイド