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J-GLOBAL ID：201802231376337043   整理番号：18A1871711

2017年に中国で出現したH7N9高病原性ウイルスの急速な進化【JST・京大機械翻訳】

Rapid Evolution of H7N9 Highly Pathogenic Viruses that Emerged in China in 2017

著者 (29件)： Shi Jianzhong (State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, Heilongjiang 150069, People’s Republic of China) ,  Deng Guohua (State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, Heilongjiang 150069, People’s Republic of China) ,  Ma Shujie (State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, Heilongjiang 150069, People’s Republic of China) ,  Zeng Xianying (State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, Heilongjiang 150069, People’s Republic of China) ,  Yin Xin (State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, Heilongjiang 150069, People’s Republic of China) ,  Li Mei (State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, Heilongjiang 150069, People’s Republic of China) ,  Zhang Bo (State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, Heilongjiang 150069, People’s Republic of China) ,  Cui Pengfei (State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, Heilongjiang 150069, People’s Republic of China) ,  Chen Yan (State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, Heilongjiang 150069, People’s Republic of China) ,  Yang Huanliang (State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, Heilongjiang 150069, People’s Republic of China) ,  Wan Xiaopeng (State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, Heilongjiang 150069, People’s Republic of China) ,  Liu Liling (State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, Heilongjiang 150069, People’s Republic of China) ,  Chen Pucheng (State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, Heilongjiang 150069, People’s Republic of China) ,  Jiang Yongping (State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, Heilongjiang 150069, People’s Republic of China) ,  Guan Yuntao (State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, Heilongjiang 150069, People’s Republic of China) ,  Liu Jinxiong (State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, Heilongjiang 150069, People’s Republic of China) ,  Gu Wenli (State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, Heilongjiang 150069, People’s Republic of China) ,  Han Shuyu (State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, Heilongjiang 150069, People’s Republic of China) ,  Song Yangming (State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, Heilongjiang 150069, People’s Republic of China) ,  Liang Libin (State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, Heilongjiang 150069, People’s Republic of China) ,  Qu Zhiyuan (State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, Heilongjiang 150069, People’s Republic of China) ,  Hou Yujie (State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, Heilongjiang 150069, People’s Republic of China) ,  Wang Xiurong (State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, Heilongjiang 150069, People’s Republic of China) ,  Bao Hongmei (State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, Heilongjiang 150069, People’s Republic of China) ,  Tian Guobin (State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, Heilongjiang 150069, People’s Republic of China) ,  Li Yanbing (State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, Heilongjiang 150069, People’s Republic of China) ,  Jiang Li (State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, Heilongjiang 150069, People’s Republic of China) ,  Li Chengjun (State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, Heilongjiang 150069, People’s Republic of China) ,  Chen Hualan (State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, Heilongjiang 150069, People’s Republic of China)
資料名： Cell Host & Microbe  (Cell Host & Microbe)
巻： 24  号： 4  ページ： 558-568.e7  発行年： 2018年 
JST資料番号： W2784A  ISSN： 1931-3128  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： オランダ (NLD)  言語： 英語 (EN)

抄録/ポイント： H7N9低病原性インフルエンザウイルスは2013年に中国で出現し,2017年に高度病原性株に変異し,ヒト感染症とニワトリにおける疾患をもたらした。拡散を制御するために,二価H5/H7不活化ワクチンを,2017年9月に家禽に導入した。ウイルス進化とワクチン有効性をモニターするために,著者らは,2017年2月から2018年1月まで中国を通して53,884の家禽サンプルを収集した。著者らは,252のH7N9低病原性ウイルス,69のH7N9高度病原性ウイルス,および1つのH7N2高度病原性ウイルスを分離し,そのうち2つの低病原性および14の高度病原性株をワクチン導入後に収集した。高度病原性株の遺伝子解析は9つの遺伝子型を明らかにし,そのうちの1つは優勢で広範で,マウスにおいて高い病原性を示す株を含んでいた。さらに,アヒルウイルス遺伝子を運ぶいくつかのH7N9およびH7N2ウイルスはアヒルにおいて致死的である。従って,ワクチン接種はH7N9感染を減少させたが,病原性の増加と宿主範囲の拡大は新しい挑戦をもたらす。Copyright 2018 Elsevier B.V., Amsterdam. All rights reserved. Translated from English into Japanese by JST.【JST・京大機械翻訳】

シソーラス用語： 感染症 ,  *病原性 ,  ヒト ,  アヒル ,  不活化ワクチン ,  ウイルス遺伝子 ,  インフルエンザウイルス ,  感染 ,  宿主域 ,  ワクチン ,  予防接種 ,  遺伝子型 ,  家禽
準シソーラス用語： 遺伝子解析 ,  ウイルス進化 , 【Automatic Indexing@JST】

著者キーワード (7件)： H7N9高病原性インフルエンザウイルス ,  進化 ,  病原性 ,  ワクチン ,  マウス ,  アヒル ,  ニワトリ

分類 (2件)： 感染症・寄生虫症一般  (GD01010H) ,  ウイルス感染の生理と病原性  (EG04042Y)

タイトルに関連する用語 (4件)： 中国 ,  病原性 ,  ウイルス ,  急速な進化