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J-GLOBAL ID：201802247162644975   整理番号：18A0394228

心筋虚血が疑われた患者における運動試験時のaVR誘導の診断的および予後的価値【Powered by NICT】

Diagnostic and Prognostic Value of Lead aVR During Exercise Testing in Patients Suspected of Having Myocardial Ischemia

著者 (49件)： Wagener Max (Department of Cardiology and Cardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland) ,  Wagener Max (University of Basel, Basel, Switzerland) ,  Abaecherli Roger (Department of Cardiology and Cardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland) ,  Abaecherli Roger (Institute of Medical Engineering, Lucerne University of Applied Sciences and Arts, Horw, Switzerland) ,  Honegger Ursina (Department of Cardiology and Cardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland) ,  Honegger Ursina (University of Basel, Basel, Switzerland) ,  Schaerli Nicolas (Department of Cardiology and Cardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland) ,  Schaerli Nicolas (University of Basel, Basel, Switzerland) ,  Pretre Gil (Department of Cardiology and Cardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland) ,  Pretre Gil (University of Basel, Basel, Switzerland) ,  Twerenbold Raphael (Department of Cardiology and Cardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland) ,  Twerenbold Raphael (University of Basel, Basel, Switzerland) ,  Twerenbold Raphael (Department of General and Interventional Cardiology, University Heart Center Hamburg, Hamburg, Germany) ,  Puelacher Christian (Department of Cardiology and Cardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland) ,  Puelacher Christian (University of Basel, Basel, Switzerland) ,  Sunier Germaine (Department of Cardiology and Cardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland) ,  Sunier Germaine (University of Basel, Basel, Switzerland) ,  Reddiess Philipp (Department of Cardiology and Cardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland) ,  Reddiess Philipp (University of Basel, Basel, Switzerland) ,  Rubini Gimenez Maria (Department of Cardiology and Cardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland) ,  Rubini Gimenez Maria (University of Basel, Basel, Switzerland) ,  Wildi Karin (Department of Cardiology and Cardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland) ,  Wildi Karin (University of Basel, Basel, Switzerland) ,  Boeddinghaus Jasper (Department of Cardiology and Cardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland) ,  Boeddinghaus Jasper (University of Basel, Basel, Switzerland) ,  Nestelberger Thomas (Department of Cardiology and Cardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland) ,  Nestelberger Thomas (University of Basel, Basel, Switzerland) ,  Badertscher Patrick (Department of Cardiology and Cardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland) ,  Badertscher Patrick (University of Basel, Basel, Switzerland) ,  Sabti Zaid (Department of Cardiology and Cardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland) ,  Sabti Zaid (University of Basel, Basel, Switzerland) ,  Schmid Ramun (Signal Processing, Schiller AG, Baar, Switzerland) ,  Leber Remo (Signal Processing, Schiller AG, Baar, Switzerland) ,  Widmer Dayana Flores (Department of Cardiology and Cardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland) ,  Widmer Dayana Flores (University of Basel, Basel, Switzerland) ,  Shrestha Samyut (Department of Cardiology and Cardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland) ,  Shrestha Samyut (University of Basel, Basel, Switzerland) ,  Strebel Ivo (Department of Cardiology and Cardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland) ,  Strebel Ivo (University of Basel, Basel, Switzerland) ,  Wild Damian (University of Basel, Basel, Switzerland) ,  Wild Damian (Division of Nuclear Medicine, University Hospital Basel, Basel, Switzerland) ,  Osswald Stefan (Department of Cardiology and Cardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland) ,  Osswald Stefan (University of Basel, Basel, Switzerland) ,  Zellweger Michael (Department of Cardiology and Cardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland) ,  Zellweger Michael (University of Basel, Basel, Switzerland) ,  Mueller Christian (Department of Cardiology and Cardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland) ,  Mueller Christian (University of Basel, Basel, Switzerland) ,  Reichlin Tobias (Department of Cardiology and Cardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland) ,  Reichlin Tobias (University of Basel, Basel, Switzerland)
資料名： American Journal of Cardiology  (American Journal of Cardiology)
巻： 119  号： 7  ページ： 959-966  発行年： 2017年 
JST資料番号： A0916B  ISSN： 0002-9149  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： オランダ (NLD)  言語： 英語 (EN)

抄録/ポイント： は,運動負荷試験中に,臨床診療においてしばしば無視鉛,aVRにおけるST偏位の診断的および予後的価値を評価し,V_5におけるST低下の最も広く使用されている基準と比較することを目的とした。自転車ストレス試験を受けた核血流イメージングのために紹介された疑い心筋虚血の1,596名の患者を登録した。リードaVRとV_5におけるST部分振幅を自動的に測定した。誘導性心筋虚血の存在は診断エンドポイントであり,核血流イメージングと冠動脈造影に基づいて判定した。死,急性心筋梗塞および冠動脈血行再建を含むフォローアップの2年間の主要有害心イベント(MACE)を予後的エンドポイントであった。運動誘発性心筋虚血は470人の患者(29%)で検出された。リードaVRとV_5のためのメディアンST振幅は,虚血(p<0.01)無しの患者間で有意に異なっていた。受信者動作特性曲線下の面積で定量化された心筋虚血のST変化の診断精度は2分回収に最も高く,aVRとV_5(0.62%,95%信頼区間CIは0.60 0.65対0.60;95%信頼区間0.58~0.63,比較のためP=0.08)で類似していた。多変量解析では,鉛V_5ではなく,リードaVRでのST変化は臨床パラメータと手動心電図解釈の上に独立な診断情報を提供した。2年間の追跡調査では,MACEはaVRでのST上昇患者の33%,なし(p<0.001)16%で発生した。結論として,運動負荷試験中のリードaVRでのST上昇は鉛V_5と臨床因子のST低下とは無関係に誘導性心筋虚血を示し,また経過観察中MACEを予測した。Copyright 2018 Elsevier B.V., Amsterdam. All rights reserved. Translated from English into Japanese by JST.【Powered by NICT】

シソーラス用語： 追跡調査 ,  信頼区間 ,  血流 ,  多変量解析 ,  負荷試験 ,  急性心筋梗塞 ,  *患者 ,  *虚血 ,  *心筋虚血 ,  冠動脈造影 ,  心電図 ,  *運動負荷 ,  画像処理
準シソーラス用語： ST上昇 ,  ST低下 , 【Automatic Indexing@JST】

分類 (1件)： 循環系の疾患  (GJ03000C)

タイトルに関連する用語 (8件)： 心筋虚血 ,  患者 ,  運動試験 ,  AVR ,  誘導 ,  診断 ,  予後 ,  価値