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J-GLOBAL ID：201802248007743614   整理番号：18A0331930

癌患者におけるQOLと身体機能の品質に及ぼす運動の効果と調節因子:34RCTの個々の患者データのメタ分析【Powered by NICT】

Effects and moderators of exercise on quality of life and physical function in patients with cancer: An individual patient data meta-analysis of 34 RCTs

著者 (54件)： Buffart Laurien M. (Department of Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, The Netherlands) ,  Buffart Laurien M. (Department of Medical Oncology, VU University Medical Center, Amsterdam, The Netherlands) ,  Kalter Joeri (Department of Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, The Netherlands) ,  Sweegers Maike G. (Department of Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, The Netherlands) ,  Courneya Kerry S. (Faculty of Physical Education and Recreation, University of Alberta, Edmonton, Canada) ,  Newton Robert U. (Exercise Medicine Research Institute, Edith Cowan University, Joondalup, WA, Australia) ,  Aaronson Neil K. (Division of Psychosocial Research and Epidemiology, Netherlands Cancer Institute, Amsterdam, The Netherlands) ,  Jacobsen Paul B. (Division of Population Science, Moffitt Cancer Center and Research Institute, Tampa, FL, USA) ,  May Anne M. (Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands) ,  Galvao Daniel A. (Exercise Medicine Research Institute, Edith Cowan University, Joondalup, WA, Australia) ,  Chinapaw Mai J. (Department of Public and Occupational Health, VU University Medical Center, Amsterdam, The Netherlands) ,  Steindorf Karen (Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Disease (NCT), Heidelberg, Germany) ,  Irwin Melinda L. (Yale School of Public Health, New Haven, USA) ,  Stuiver Martijn M. (Department of Physiotherapy, Netherlands Cancer Institute, Amsterdam, The Netherlands) ,  Hayes Sandi (School of Public Health, Institute of Health and Biomedical Innovation, Queensland University of Technology, Kelvin Grove, QLD, Australia) ,  Griffith Kathleen A. (School of Nursing, University of Maryland, Baltimore, USA) ,  Lucia Alejandro (European University, Madrid, Spain) ,  Mesters Ilse (Department of Epidemiology, Maastricht University, The Netherlands) ,  van Weert Ellen (University Medical Centre Groningen, University of Groningen, Center for Rehabilitation, Groningen, The Netherlands) ,  Knoop Hans (Department of Medical Psychology, Academic Medical Center, Amsterdam, The Netherlands) ,  Goedendorp Martine M. (Department of Health Psychology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands) ,  Mutrie Nanette (Physical Activity for Health Research Center, University of Edinburgh, Edinburgh, UK) ,  Daley Amanda J. (Primary Care Clinical Sciences, School of Health and Population Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK) ,  McConnachie Alex (Institute of Health and Wellbeing, University of Glasgow, Glasgow, UK) ,  Bohus Martin (Institute of Psychiatric and Psychosomatic Psychotherapy, Central Institute of Mental Health, Heidelberg University, Mannheim, Germany) ,  Bohus Martin (Faculty of Health, University of Antwerp, Belgium) ,  Thorsen Lene (National Advisory Unit on Late Effects after Cancer, Department of Oncology, Oslo University Hospital, Oslo, Norway) ,  Schulz Karl-Heinz (Athleticum - Competence Center for Sports- and Exercise Medicine and Institute for Medical Psychology, University Medical Center Hamburg-Eppendorf, Germany) ,  Short Camille E. (Freemasons Foundation Centre of Men’s Health, School of Medicine, University of Adelaide, SA, Australia) ,  James Erica L. (School of Medicine & Public Health, the University of Newcastle, Callaghan, NSW, Australia) ,  Plotnikoff Ron C. (Priority Research Centre for Physical Activity and Nutrition, the University of Newcastle, Callaghan, NSW, Australia) ,  Arbane Gill (Lane Fox Respiratory Research Unit, Guy’s and St Thomas’ NHS Foundation Trust, London, UK) ,  Schmidt Martina E. (Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Disease (NCT), Heidelberg, Germany) ,  Potthoff Karin (Department of Medical Oncology, National Center for Tumor Diseases (NCT) and Heidelberg University Hospital, Heidelberg, Germany) ,  Potthoff Karin (Department of Radiation Oncology, National Center for Tumor Diseases (NCT) and Heidelberg University Hospital, Heidelberg, Germany) ,  van Beurden Marc (Netherlands Cancer Institute/Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands) ,  Oldenburg Hester S. (Netherlands Cancer Institute/Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands) ,  Sonke Gabe S. (Netherlands Cancer Institute/Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands) ,  van Harten Wim H. (Division of Psychosocial Research and Epidemiology, Netherlands Cancer Institute, Amsterdam, The Netherlands) ,  van Harten Wim H. (University of Twente, Enschede, The Netherlands) ,  Garrod Rachel (Department of Respiratory Medicine, Kings College London, London, UK) ,  Schmitz Kathryn H. (Penn State Health, College of Medicine, and Cancer Institute, Hershey, PA, USA) ,  Winters-Stone Kerri M. (Oregon Health & Science University, Portland, USA) ,  Velthuis Miranda J. (Netherlands Comprehensive Cancer Organisation (IKNL), Utrecht, the Netherlands) ,  Taaffe Dennis R. (Exercise Medicine Research Institute, Edith Cowan University, Joondalup, WA, Australia) ,  van Mechelen Willem (Department of Public and Occupational Health, VU University Medical Center, Amsterdam, The Netherlands) ,  Kersten Marie-Jose (Department of Hematology, Academic Medical Center, Amsterdam, The Netherlands) ,  Nollet Frans (Department of Rehabilitation Medicine, Academic Medical Center, Amsterdam, The Netherlands) ,  Wenzel Jennifer (Johns Hopkins School of Nursing, Johns Hopkins School of Medicine, Sidney Kimmel Comprehensive Cancer Center, Baltimore, USA) ,  Wiskemann Joachim (Lane Fox Respiratory Research Unit, Guy’s and St Thomas’ NHS Foundation Trust, London, UK) ,  Verdonck-de Leeuw Irma M. (Department of Otolaryngology-Head and Neck Surgery, VU University Medical Center, Amsterdam, The Netherlands) ,  Verdonck-de Leeuw Irma M. (Department of Clinical Psychology, Vrije Universiteit Amsterdam, The Netherlands) ,  Brug Johannes (Department of Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, The Netherlands) ,  Brug Johannes (Amsterdam School of Communication Research (ASCoR), University of Amsterdam, Amsterdam, The Netherlands)
資料名： Cancer Treatment Reviews  (Cancer Treatment Reviews)
巻： 52  ページ： 91-104  発行年： 2017年 
JST資料番号： W1768A  ISSN： 0305-7372  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： オランダ (NLD)  言語： 英語 (EN)

抄録/ポイント： 個々の患者データのメタ解析は癌患者におけるクオリティオブライフ(QoL)と身体機能(PF)の品質に及ぼす運動の効果を評価するために,個体群統計学の減速材効果(年齢,性別,婚姻状態,教育),臨床的(ボディマスインデックス,癌型,転移の有無),介入と関係(介入時期,分娩様式と持続時間,および型対照群),運動(運動周波数,強度,タイプ,時間)特性を同定することを目的とした。PubMed,EMBASE,PsycINFO,CINAHL,参照検査とパーソナル通信を介した2012年9月で同定された関連する公開及び未公開研究。すべて69の適格試験の原理の研究者はその研究からIPDを共有するように依頼した。癌の成人患者におけるQoLとPFに通常ケアと比較しての運動,待機リストまたは注意対照群の影響を評価した34件の無作為化対照試験(4519名の患者)からIPDを検索し,プールした。線形混合効果モデルはベースライン値の調整介入後結果値(zスコア)に及ぼす運動の影響を評価するために用いた。減速材効果は試験相互作用により研究した。運動QoL(β=0.15, 95%CI=0.10;0.20)およびPF(β=0.18, 95%CI=0.13;0.23)は有意に改善した。効果は人口統計学的,臨床的または運動特性により緩和されなかった。QoL(β_difference_in_effect=0.13;95%CI=0.03;0.22)およびPF(β_difference_in_effect=0.10;95%CI=0.01;0.20)に及ぼす影響は教師なし介入よりも教師つきで有意に大きかった。結論として,特に監視下運動,運動中と治療後の異なる人口統計学的および臨床的特性を有する癌患者におけるQoLとPFを効果的に改善する。効果サイズが小さいが,癌治療の一部としての運動の実施を支援するための一貫した経験的証拠がある。Copyright 2018 Elsevier B.V., Amsterdam. All rights reserved. Translated from English into Japanese by JST.【Powered by NICT】

シソーラス用語： 継続時間 ,  治療法 ,  教育 ,  クオリティオブライフ ,  ボディマスインデックス ,  ランダム化比較試験 ,  *品質 ,  *患者 ,  成人 ,  *メタ分析
準シソーラス用語： 人口統計学 ,  *患者情報 ,  *運動効果 ,  *身体機能 ,  *癌患者 , 【Automatic Indexing@JST】

著者キーワード (5件)： 運動 ,  生活の質 ,  身体機能 ,  Neoplasm ,  個々の患者データのメタ分析

分類 (5件)： 運動器系の臨床医学一般  (GG01030M) ,  臨床診断学  (GC03003G) ,  血液疾患の治療一般  (GK05010E) ,  小児に特有の疾患  (GC08020M) ,  その他の騒音・振動  (SB04040P)

タイトルに関連する用語 (7件)： 癌患者 ,  QOL ,  身体機能 ,  運動の効果 ,  調節因子 ,  患者データ ,  メタ分析