文献

J-GLOBAL ID：201802272066511147   整理番号：18A0827485

アルテスネートのpHおよび酸素依存性酸化活性のメカニズム

Mechanisms of the pH- and Oxygen-Dependent Oxidation Activities of Artesunate

著者 (12件)： Tsuda Katsunori (Department of Medical Pharmacology, Institute of Biomedical Sciences, University of Tokushima Graduate School) ,  Miyamoto Licht (Department of Medical Pharmacology, Institute of Biomedical Sciences, University of Tokushima Graduate School) ,  Hamano Shuichi (Department of Cell and Immunity Analytics, Institute of Biomedical Sciences, University of Tokushima Graduate School) ,  Morimoto Yuri (Major in Laboratory Science, School of Health Sciences, Faculty of Medicine, Tokushima University) ,  Kangawa Yumi (Major in Laboratory Science, School of Health Sciences, Faculty of Medicine, Tokushima University) ,  Fukue Chika (Major in Laboratory Science, School of Health Sciences, Faculty of Medicine, Tokushima University) ,  Kagawa Yoko (Major in Laboratory Science, School of Health Sciences, Faculty of Medicine, Tokushima University) ,  Horinouchi Yuya (Department of Pharmacology, Institute of Biomedical Sciences, University of Tokushima Graduate School) ,  Xu Wenting (Department of Medical Pharmacology, Institute of Biomedical Sciences, University of Tokushima Graduate School) ,  Ikeda Yasumasa (Department of Pharmacology, Institute of Biomedical Sciences, University of Tokushima Graduate School) ,  Tamaki Toshiaki (Department of Pharmacology, Institute of Biomedical Sciences, University of Tokushima Graduate School) ,  Tsuchiya Koichiro (Department of Medical Pharmacology, Institute of Biomedical Sciences, University of Tokushima Graduate School)
資料名： Biological and Pharmaceutical Bulletin (Web)  (Biological and Pharmaceutical Bulletin (Web))
巻： 41  号： 4  ページ： 555-563(J-STAGE)  発行年： 2018年 
JST資料番号： U1402A  ISSN： 1347-5215  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： 日本 (JPN)  言語： 英語 (EN)

抄録/ポイント： アルテミシニンは1971年にヨモギ属の植物(Artemisi...

シソーラス用語： ヒト ,...
準シソーラス用語： Artemisia annua

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著者キーワード (10件)： artesunate ,  iron ,  reactive oxygen species (ROS) ,  cancer ,  electron paramagnetic resonance (EPR) ,  artesunate ,  iron ,  reactive oxygen species (ROS) ,  cancer ,  electron paramagnetic resonance (EPR)

分類 (2件)： 生薬一般  (GX06010Y) ,  抗腫よう薬の基礎研究  (GW16010A)

物質索引 (2件)： アルテスナート ,  アルテミシニン

引用文献 (68件)：

• 1) Sherman IW. Biochemistry of Plasmodium (malarial parasites). Microbiol. Rev., 43, 453-495 (1979).
• 2) WHO. “World Malaria Report 2016.”: ‹http://www.who.int/malaria/publications/world-malaria-report-2016/report/en/›.
• 3) WHO. Guidelines for the treatment of malaria. Third edition. (2015).
• 4) Klayman DL. Qinghaosu (artemisinin): an antimalarial drug from China. Science, 228, 1049-1055 (1985).
• 5) Asano M, Iwahashi H. Determination of the structures of radicals formed in the reaction of antimalarial drug artemisinin with ferrous ions. Eur. J. Med. Chem., 127, 740-747 (2017).

タイトルに関連する用語 (6件)： pH ,  酸素 ,  依存性 ,  酸化 ,  活性 ,  メカニズム