文献

J-GLOBAL ID：201802275832650696   整理番号：18A1850819

慢性圧負荷はマウスにおいてSGLT1およびIL-18遺伝子発現の増加を介し心肥大および線維症を誘導する

Chronic Pressure Overload Induces Cardiac Hypertrophy and Fibrosis via Increases in SGLT1 and IL-18 Gene Expression in Mice

著者 (13件)： Matsushita Naoko (Division of Cardiology, Department of Internal Medicine, Iwate Medical University School of Medicine) ,  Ishida Nanae (Department of Molecular and Cellular Pharmacology, Iwate Medical University School of Pharmaceutical Sciences) ,  Ibi Miho (Department of Molecular and Cellular Pharmacology, Iwate Medical University School of Pharmaceutical Sciences) ,  Saito Maki (Department of Molecular and Cellular Pharmacology, Iwate Medical University School of Pharmaceutical Sciences) ,  Sanbe Atsushi (Department of Pharmacotherapy, Iwate Medical University School of Pharmaceutical Sciences) ,  Shimojo Hisashi (Department of Pathology, Shinshu University School of Medicine) ,  Suzuki Satoshi (Department of Cardiology and Hematology, Fukushima Medical University) ,  Koepsell Hermann (Department of Molecular Plant Physiology and Biophysics, Julius-von-Sachs-Institute, University of Wuerzburg) ,  Takeishi Yasuchika (Department of Cardiology and Hematology, Fukushima Medical University) ,  Morino Yoshihiro (Division of Cardiology, Department of Internal Medicine, Iwate Medical University School of Medicine) ,  Taira Eiichi (Department of Pharmacology, Iwate Medical University School of Medicine) ,  Sawa Yohei (Division of Cardiology, Department of Internal Medicine, Iwate Medical University School of Medicine) ,  Hirose Masamichi (Department of Molecular and Cellular Pharmacology, Iwate Medical University School of Pharmaceutical Sciences)
資料名： International Heart Journal (Web)  (International Heart Journal (Web))
巻： 59  号： 5  ページ： 1123-1133(J-STAGE)  発行年： 2018年 
JST資料番号： U1357A  ISSN： 1349-3299  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： 日本 (JPN)  言語： 英語 (EN)

抄録/ポイント： ナトリウム-グルコース共輸送体1(SGLT1)の遺伝子発現増...

シソーラス用語： *負荷 ,...
準シソーラス用語： *慢性圧負荷 ,...

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著者キーワード (2件)： 高血圧 ,  心筋症

分類 (1件)： 循環系の基礎医学  (GJ01020K)

引用文献 (39件)：

• 1. Levy D, Garrison RJ, Savage DD, Kannel WB, Castelli WP. Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study. N Engl J Med 1990; 322: 1561-6.
• 2. Rapacciuolo A, Esposito G, Caron K, Mao L, Thomas SA, Rockman HA. Important role of endogenous norepinephrine and epinephrine in the development of in vivo pressure overload cardiac hypertrophy. J Am Coll Cardiol 2001; 38: 876-82.
• 3. Rockman HA, Wachhorst SP, Mao L, Ross J Jr. ANG II receptor blockade prevents ventricular hypertrophy and ANF gene expression with pressure overload in mice. Am J Physiol 1994; 266: H2468-75.
• 4. Katanasaka Y, Suzuki H, Sunagawa Y, Hasegawa K, Morimoto T. Regulation of cardiac transcription factor GATA4 by post-translational modification in cardiomyocyte hypertrophy and heart failure. Int Heart J 2016; 57: 672-5.
• 5. Niizeki T, Takeishi Y, Kitahara T, et al. Diacylglycerol kinase-epsilon restores cardiac dysfunction under chronic pressure overload: a new specific regulator of Galpha (q) signaling cascade. Am J Physiol Heart Circ Physiol 2008; 295: H245-55.

タイトルに関連する用語 (9件)： 慢性 ,  圧負荷 ,  マウス ,  SGLT1 ,  IL-18 ,  遺伝子発現 ,  心肥大 ,  線維症 ,  誘導