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J-GLOBAL ID：201802292931878066   整理番号：18A0129673

子供時代の知能,社会的背景および頭蓋内容積のための整合73と92歳の間の脳構造の違い【Powered by NICT】

Brain structural differences between 73- and 92-year olds matched for childhood intelligence, social background, and intracranial volume

著者 (48件)： Ritchie Stuart J. (Department of Psychology, The University of Edinburgh, Edinburgh, UK) ,  Ritchie Stuart J. (Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK) ,  Dickie David Alexander (Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary & Life Sciences, University of Glasgow, Glasgow, UK) ,  Dickie David Alexander (Brain Research Imaging Centre, the University of Edinburgh, Edinburgh, UK) ,  Dickie David Alexander (Scottish Imaging Network, A Platform for Scientific Excellence (SINAPSE) Collaboration) ,  Dickie David Alexander (Centre for Clinical Brain Sciences, The University of Edinburgh, Edinburgh, UK) ,  Cox Simon R. (Department of Psychology, The University of Edinburgh, Edinburgh, UK) ,  Cox Simon R. (Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK) ,  Valdes Hernandez Maria del C. (Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK) ,  Valdes Hernandez Maria del C. (Brain Research Imaging Centre, the University of Edinburgh, Edinburgh, UK) ,  Valdes Hernandez Maria del C. (Scottish Imaging Network, A Platform for Scientific Excellence (SINAPSE) Collaboration) ,  Valdes Hernandez Maria del C. (Centre for Clinical Brain Sciences, The University of Edinburgh, Edinburgh, UK) ,  Sibbett Ruth (Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK) ,  Sibbett Ruth (Alzheimer Scotland Dementia Research Centre, The University of Edinburgh, Edinburgh, UK) ,  Pattie Alison (Department of Psychology, The University of Edinburgh, Edinburgh, UK) ,  Anblagan Devasuda (Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK) ,  Anblagan Devasuda (Scottish Imaging Network, A Platform for Scientific Excellence (SINAPSE) Collaboration) ,  Anblagan Devasuda (Centre for Clinical Brain Sciences, The University of Edinburgh, Edinburgh, UK) ,  Redmond Paul (Department of Psychology, The University of Edinburgh, Edinburgh, UK) ,  Royle Natalie A. (Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK) ,  Royle Natalie A. (Brain Research Imaging Centre, the University of Edinburgh, Edinburgh, UK) ,  Royle Natalie A. (Scottish Imaging Network, A Platform for Scientific Excellence (SINAPSE) Collaboration) ,  Royle Natalie A. (Centre for Clinical Brain Sciences, The University of Edinburgh, Edinburgh, UK) ,  Corley Janie (Department of Psychology, The University of Edinburgh, Edinburgh, UK) ,  Corley Janie (Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK) ,  Maniega Susana Munoz (Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK) ,  Maniega Susana Munoz (Brain Research Imaging Centre, the University of Edinburgh, Edinburgh, UK) ,  Maniega Susana Munoz (Scottish Imaging Network, A Platform for Scientific Excellence (SINAPSE) Collaboration) ,  Maniega Susana Munoz (Centre for Clinical Brain Sciences, The University of Edinburgh, Edinburgh, UK) ,  Taylor Adele M. (Department of Psychology, The University of Edinburgh, Edinburgh, UK) ,  Karama Sherif (Department of Neurology and Neurosurgery, McConnell Brain Imaging Center, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada) ,  Karama Sherif (Department of Psychiatry, Douglas Mental Health University Institute, McGill University, Verdun, Quebec, Canada) ,  Booth Tom (Department of Psychology, The University of Edinburgh, Edinburgh, UK) ,  Booth Tom (Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK) ,  Gow Alan J. (Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK) ,  Gow Alan J. (Department of Psychology, Heriot-watt University, Edinburgh, UK) ,  Starr John M. (Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK) ,  Starr John M. (Alzheimer Scotland Dementia Research Centre, The University of Edinburgh, Edinburgh, UK) ,  Bastin Mark E. (Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK) ,  Bastin Mark E. (Brain Research Imaging Centre, the University of Edinburgh, Edinburgh, UK) ,  Bastin Mark E. (Scottish Imaging Network, A Platform for Scientific Excellence (SINAPSE) Collaboration) ,  Bastin Mark E. (Centre for Clinical Brain Sciences, The University of Edinburgh, Edinburgh, UK) ,  Wardlaw Joanna M. (Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK) ,  Wardlaw Joanna M. (Brain Research Imaging Centre, the University of Edinburgh, Edinburgh, UK) ,  Wardlaw Joanna M. (Scottish Imaging Network, A Platform for Scientific Excellence (SINAPSE) Collaboration) ,  Wardlaw Joanna M. (Centre for Clinical Brain Sciences, The University of Edinburgh, Edinburgh, UK) ,  Deary Ian J. (Department of Psychology, The University of Edinburgh, Edinburgh, UK) ,  Deary Ian J. (Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK)
資料名： Neurobiology of Aging  (Neurobiology of Aging)
巻： 62  ページ： 146-158  発行年： 2018年 
JST資料番号： W0356A  ISSN： 0197-4580  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： オランダ (NLD)  言語： 英語 (EN)

抄録/ポイント： 脳における年齢差を特性化する完全加齢関連認知機能低下に対抗するための重要な課題である。二つの独立した,狭い年齢コホートに傾向スコアマッチングを用いて,小児期認知能力,社会経済的背景,および頭蓋内体積に関するデータを用いて平均年齢73歳(n=126)で非常に類似した参加者の平均年齢は92歳(n=42)の参加者と一致する。種々の全体的および局所的構造的神経画像変数の調査は,灰白質および白質の体積,皮質表面積,皮質の厚さ,および白質高信号体積と空間的広がりにおける大きな差があった。媒介分析では,白質高信号および全皮質表面積の全体積は,年齢と一般的認知能力の間の関係(組織容積と皮質厚さがこの分析における重要なメディエーターではない)の24.9%を仲介した。これらの知見は,neurostructural加齢,第八と第十の生活から脳を同じ認知的,社会経済的,および脳体積出発点にもかかわらず大きく異なるに異常で,貴重な視点を提供する。Copyright 2018 Elsevier B.V., Amsterdam. All rights reserved. Translated from English into Japanese by JST.【Powered by NICT】

シソーラス用語： 灰白質 ,  *子供 ,  母集団 ,  表面積 ,  キャラクタリゼーション ,  白質 ,  年齢差 ,  皮質
準シソーラス用語： ニューロイメージング ,  社会経済 ,  認知能力 ,  認知障害 ,  *脳構造 ,  *頭蓋 ,  *社会的背景 , 【Automatic Indexing@JST】

著者キーワード (5件)： 加齢 ,  構造的MRI ,  脳体積 ,  白質高信号域 ,  病変マッピング

分類 (2件)： 神経系の診断  (GN02000H) ,  中枢神経系  (EJ12030F)

タイトルに関連する用語 (7件)： 子供 ,  知能 ,  社会的背景 ,  頭蓋 ,  容積 ,  整合 ,  脳構造