研究キーワード (3件):
peptide engineering
, origin of life
, RNA polymerase
競争的資金等の研究課題 (5件):
2022 - 2027 非生命的原始タンパク質誕生可能性の探索
2018 - 2023 初期生命におけるRNA・タンパク質共進化プロセスの再現
2017 - 2020 ポリメラーゼ・ヌクレアーゼ活性変換因子の開発
2016 - 2018 原始RNAポリメラーゼの探求のための試験管内進化実験
2011 - 2011 RNAポリメラーゼの構造変化による転写調節の解明
論文 (18件):
Anastasiia Chaban, Leonid Minakhin, Ekaterina Goldobina, Brain Bae, Yue Hao, Sergei Borukhov, Leena Putzeys, Maarten Boon, Florian Kabinger, Rob Lavigne, et al. Tail-tape-fused virion and non-virion RNA polymerases of a thermophilic virus with an extremely long tail. Nature Communications. 2024
Sota Yagi, Shunsuke Tagami. Missing-link fold reveals the evolutionary pathway between RNA polymerase and ribosomal proteins. 2023
Shunsuke Tagami, Peiying Li. The origin of life: RNA and protein co-evolution on the ancient Earth. Development, growth & differentiation. 2023. 65. 3. 167-174
Shunsuke Tagami. Why we are made of proteins and nucleic acids: Structural biology views on extraterrestrial life. Biophysics and Physicobiology. 2023
Kohta Mohri, Kim Phuong Huynh Nhat, Maki Zouda, Shota Warashina, Yasuhiro Wada, Yasuyoshi Watanabe, Shunsuke Tagami, Hidefumi Mukai. Lasso peptide microcin J25 variant containing RGD motif as a PET probe for integrin αvβ3 in tumor imaging. European Journal of Pharmaceutical Sciences. 2022. 180. 106339-106339