2020 - 2023 Study of liver restorative therapy for a murine nonalcoholic steatohepatitis model by the administration of immune-suppressive fractions of autologous adipose tissue-derived stromal cells
2021 - 2022 Bispecific抗体を用いた膵癌免疫療法の開発
2014 - 2017 脂肪組織由来間質細胞群の細胞分画特性解析と肝修復再生療法の開発
論文 (23件)：
Alessandro Nasti, Miki Okumura, Yumie Takeshita, Tuyen Thuy Bich Ho, Yoshio Sakai, Taka-Aki Sato, Chiaki Nomura, Hisanori Goto, Yujiro Nakano, Takeshi Urabe, et al. The declining insulinogenic index correlates with inflammation and metabolic dysregulation in non-obese individuals assessed by blood gene expression. Diabetes Research and Clinical Practice. 2024. 111090-111090
Alessandro Nasti, Masaki Miyazawa, Akihiro Seki, Tuyen Thuy Bich Ho, Riei Tsurumi, Miu Awaki, Yoshio Sakai, Shuichi Kaneko. Bioinformatics Methods for the Identification of Treatment Response Prediction Markers in Pancreatic Cancer. SoMeT. 2023. 1-11
Akihiro Seki, Yoshio Sakai, Alessandro Nasti, Norihiko Ogawa, Eishiro Mizukoshi. In Abstracts: (2425) Mesenchymal stromal cells restore the NASH by ameliorating ER stress of hepatocytes derived from hepatic stellate cells. Hepatology. 2022. 76. S1. S1-S1564
Masaaki Yano*, Alessandro Nasti*, Akihiro Seki, Kosuke Ishida, Masatoshi Yamato, Hiiro Inui, Norihiko Ogawa, Shingo Inagaki, Tuyen Thuy Bich Ho, Kazunori Kawaguchi, et al. Characterization of adipose tissue-derived stromal cells of mice with nonalcoholic fatty liver disease and their use for liver repair. Regenerative therapy. 2021. 18. 497-507
Yoshio Sakai*, Alessandro Nasti*, Yumie Takeshita, Miki Okumura, Shinji Kitajima, Masao Honda, Takashi Wada, Seiji Nakamura, Toshinari Takamura, Takuro Tamura, et al. Eight-year longitudinal study of whole blood gene expression profiles in individuals undergoing long-term medical follow-up. Scientific Reports. 2021. 11. 1. 16564-16564
Pharmaceutical compositions based on porous zeolites as release means of pharmacologically active molecules and relative use.
書籍 (4件)：
BIOINFORMATIC ANALYSIS OF BLOOD GENE EXPRESSION FOR COMBINATION IMMUNOTHERAPY EVALUATION IN MURINE MODEL OF PANCREATIC CANCER
World Research Library, Proceedings of ResearchWorld International Conference, Rome, Italy, 25th - 26th September 2023 2023
BIOINFORMATICS METHODS FOR THE CHARACTERIZATION OF MURINE ADIPOSE-TISSUE DERIVED STROMAL CELLS ALTERED BY CONTINUOUS ROTATION SUSPENSION
World Research Library, Proceedings of ResearchWorld International Conference, Rome, Italy, 25th - 26th September 2023 2023
マウス脂肪組織由来ストローマ細胞におけるCD45+分画には,免疫抑制性炎症細胞が存在する
2018
Thesis: Chitosan-based nanoparticles and microparticles
2008
講演・口頭発表等 (50件)：
BIOINFORMATIC ANALYSIS OF BLOOD GENE EXPRESSION FOR COMBINATION IMMUNOTHERAPY EVALUATION IN MURINE MODEL OF PANCREATIC CANCER
(RW- 1541st International Conference on Internet Technologies and Society (ICITS) 2023)
BIOINFORMATICS METHODS FOR THE CHARACTERIZATION OF MURINE ADIPOSE-TISSUE DERIVED STROMAL CELLS ALTERED BY CONTINUOUS ROTATION SUSPENSION
(RW- 1541st International Conference on Internet Technologies and Society (ICITS) 2023)
Bioinformatics methods for the identification of treatment response prediction markers in pancreatic cancer
(The 22nd International Conference on Intelligent Software Methodologies, Tools and Techniques 2023)
Novel diagnostic/prediction systems and combination immunotherapies for pancreatic cancer.
(2nd Symposium of the Association of Italian Researchers in Japan 2023)
2011 - 2018 Kanazawa University Graduate School of Medical Science. Department of Graduate School of Advanced Preventive Medical Sciences (System Biology), Kanazawa, Japan PhD in Medical Sciences
2006 - 2008 The University of Manchester School of Pharmacy and Pharmaceutical Sciences. Laboratory of Polymers and Biomaterials, Manchester, UK Doctoral study exchange programme
2005 - 2008 Università degli Studi di Napoli Federico II Faculty of Pharmacy, Napoli, Italy PhD in Medicinal Chemistry
1999 - 2004 Università degli Studi di Napoli Federico II Faculty of Pharmacy, Napoli, Italy Master of Sciences of Pharmacy (MPharm)
2002 - 2003 Procter & Gamble Italian Research Center, Pescara, Italy Research Internship
2001 - 2002 Université De Nantes Faculté de Pharmacie, Nantes, France Socrates/Erasmus exchange programme
全件表示
学位 (3件)：
PhD in Medical Sciences (Kanazawa University; Kanazawa, JAPAN)
PhD in Medicinal Chemistry (University of Naples Federico II; Naples, ITALY)
Master in Pharmacy (University of Naples Federico II; Naples, ITALY)
経歴 (3件)：
2011/10 - 現在 Kanazawa University Institute of Medical, Pharmaceutical and Health Sciences; System Biology, Kanazawa, Japan Engaged in the research of immunotherapies for the diseases of the gastrointestinal tract: specifically for liver and intestinal diseases. Postdoctoral Researcher
2009/05 - 2011/09 Lincoln County Hospital, UK National Health Service (NHS), Lincoln, UK Provided service to wards and departments, exercised professional supervision over clinical use of drugs in patients. Rotational Clinical Pharmacist
2009/03 - 2009/04 The University of Manchester, School of Pharmacy and Pharmaceutical Sciences. Laboratory of Polymers and Biomaterials, Manchester, UK Support and supervision of PhD students. Focused on the preparation of biocompatible nanoparticles and microparticles for drug delivery. Honorary Research Associate
受賞 (1件)：
2021/02 - 金沢大学 Papers of the Monthプロ ジェクト 膵癌肝転移マウスモデルに対する化学療法併用の有効性を解明 〜 膵臓がんの効果的な化学療法の確立へ向けて 〜
