研究キーワード (11件):
anti-fouling
, biocompatible coating
, nanoreactor
, vesicle
, protein delivery
, Gene therapy
, Nano-Bio interfaces
, in vivo drug delivery
, Nanomedicine
, Self-assembly
, Polymer
競争的資金等の研究課題 (4件):
2023 - 2026 Development of Reversible Double-Layer Polymer Modification Technology to Break the Safety/Efficacy Trade-Off of Delivering Enzyme
2023 - 2024 Deciphering the biophysical drivers of liquid-liquid phase separation of proteins in confined conditions
2020 - 2023 Therapeutic polymer nanoreactor with site-specific activation of targeting Warburg metabolism for metastatic breast cancer treatment
2017 - 2020 腫瘍内で薬剤を長期間にわたって生成するナノリアクタシステムの構築
論文 (48件):
Saed Abassi, Anjaneyulu Dirisala, Daniel Gonzalez-Carter, West Kristian Paraiso, Junjie Li, Theofilus A. Tockary. Navigating the nanoscale: Principles of body navigation. Nanotechnology Tools for Infection Control. 2025
Bingyuan Fei, Yuewu Zhao, Jine Wang, Panyue Wen, Junjie Li, Masaru Tanaka, Zheng Wang, Shuo Li. Leveraging Adrenergic Receptor Blockade for Enhanced Nonalcoholic Fatty Liver Disease Treatment via a Biomimetic Nanoplatform. Journal of Nanobiotechnology. 2024. 22. 1
Shuting Zuo, Zhenyu Wang, Xiaoman Jiang, Yuewu Zhao, Panyue Wen, Jine Wang, Junjie Li, Masaru Tanaka, Shao Dan, Yan Zhang, et al. Regulating tumor innervation by nanodrugs potentiates cancer immunochemotherapy and relieve chemotherapy-induced neuropathic pain. Biomaterials. 2024. 122603-122603
Joachim F. R. Van Guyse, Saed Abbasi, Kazuko Toh, Zlata Nagorna, Junjie Li, Anjaneyulu Dirisala, Sabina Quader, Satoshi Uchida, Kazunori Kataoka. Facile generation of heterotelechelic poly(2-oxazoline)s towards accelerated exploration of poly(2-oxazoline)-based nanomedicine. Angewandte Chemie International Edition. 2024
Horacio Cabral, Junjie Li, Kanjiro Miyata, Kazunori Kataoka. Controlling the biodistribution and clearance of nanomedicines. Nature Reviews Bioengineering. 2023
Junjie Li, Zhishen Ge. Enzyme-responsive asymmetric polymersomes with triggered apoptosis-mimicking flip-flop of cell-penetrating inner shells. JOURNAL OF CONTROLLED RELEASE. 2017. 259. E194-E194
Zhishen Ge, Junjie Li, Yang Li. Novel stimuli-responsive block copolymers as nonviral gene delivery vectors for efficiently overcoming physiologic barriers. NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE. 2016. 12. 2. 532-532
書籍 (1件):
Thermo-responsive polyplex micelles with PEG shells and PNIPAM layer to protect DNA cores for systemic gene therapy
Humana Press, New York, NY
講演・口頭発表等 (2件):
Enzyme-responsive asymmetric polymersomes with triggered apoptosis-mimicking flip-flop of cell-penetrating inner shells
(4th Symposium on Innovative Polymers for Controlled Delivery (SIPCD 2016) 2016)
Novel stimuli-responsive block copolymers as nonviral gene delivery vectors for efficiently overcoming physiologic barriers
(the 1st International Conference on Nanomedicine (ChinaNanomedicine 2015, Hangzhou, China) 2016)
学歴 (2件):
2012 - 2017 University of Science and Technology of China (USTC) PhD in Chemistry
2008 - 2012 Anhui University (AHU) B.E. in Polymer Material and Engineering
経歴 (4件):
2022/08 - 現在 九州大学 先導物質化学研究所 准教授
2019/10 - 2022/07 Innovation Center of NanoMedicine (iCONM), Kawasaki Institute of Industrial Promotion Research Scientist
2017/10 - 2019/10 Innovation Center of NanoMedicine (iCONM), Kawasaki Institute of Industrial Promotion JSPS Postdoctoral Research Fellow
2017/02 - 2017/04 Innovation Center of NanoMedicine (iCONM), Kawasaki Institute of Industrial Promotion Visiting Researcher