研究者
J-GLOBAL ID:201901014079214880   更新日: 2024年10月02日

伊藤 智彦

Tomohiro Ito
所属機関・部署:
研究分野 (4件): 衛生学、公衆衛生学分野:実験系を含まない ,  衛生学、公衆衛生学分野:実験系を含む ,  化学物質影響 ,  放射線影響
研究キーワード (7件): ナノプラスチック粒子 ,  神経発達毒性 ,  環境汚染物質 ,  化学物質 ,  免疫 ,  発達毒性 ,  多能性幹細胞
競争的資金等の研究課題 (4件):
  • 2020 - 2023 多面的指標を用いた神経発達毒性の新たな評価系の構築
  • 2015 - 2019 エピジェネティック活性をもつ化学物質の影響把握と新たな環境リスクの予防策
  • 2016 - 2018 基底膜を利用したiPS細胞由来肺胞上皮細胞の分化培養法の開発
  • 2010 - 2011 iPS細胞を用いた造血幹細胞に対する化学物質の毒性影響評価
論文 (35件):
  • Tomohiro Ito, Xian-Yang Qin, Yoshika Kurokawa, Yang Zeng, Satoshi Otsuka, Wenlong Wang, Hideko Sone. Glial differentiation of mouse embryonic-stem-cell-derived neuronal precursors is a sensitive marker for assessing developmental neurotoxicity of insecticides. Fundamental Toxicological Sciences. 2024. 11. 3. 87-98
  • Mari Katsura, Yoshihiro Urade, Hiroko Nansai, Mika Kobayashi, Akashi Taguchi, Yukiko Ishikawa, Tomohiro Ito, Hisako Fukunaga, Hideto Tozawa, Yoko Chikaoka, et al. Low-dose radiation induces unstable gene expression in developing human iPSC-derived retinal ganglion organoids. Scientific reports. 2023. 13. 1. 12888-12888
  • Satoshi Otsuka, Xian-Yang Qin, Wenlong Wang, Tomohiro Ito, Hiroko Nansai, Kuniya Abe, Wataru Fujibuchi, Yoichi Nakao, Hideko Sone. iGEM as a human iPS cell-based global epigenetic modulation detection assay provides throughput characterization of chemicals affecting DNA methylation. Scientific reports. 2023. 13. 1. 6663-6663
  • Wenlong Wang, Tomohiro Ito, Satoshi Otsuka, Hiroko Nansai, Kuniya Abe, Yoichi Nakao, Jun Ohgane, Minoru Yoneda, Hideko Sone. Epigenetic effects of insecticides on early differentiation of mouse embryonic stem cells. Toxicology in Vitro. 2021. 75. 105174-105174
  • Akihiro Fushimi, Daisuke Nakajima, Akiko Furuyama, Go Suzuki, Tomohiro Ito, Kei Sato, Yuji Fujitani, Yoshinori Kondo, Ayako Yoshino, Sathiyamurthi Ramasamy, et al. Source contributions to multiple toxic potentials of atmospheric organic aerosols. Science of The Total Environment. 2021. 773. 145614-145614
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MISC (3件):
  • K Nohara, S Tsukumo, T Ito, M Yamamoto, H Motohashi, A Hida, Y Fujii-Kuriyama, K Inouye, H Nagai, C Tohyama. Thymocyte alterations in CD2-driven constitutively active arylhydrocarbon receptor (AhR) transgenic mice. TOXICOLOGICAL SCIENCES. 2003. 72. 362-362
  • T Ito, S Tsukumo, M Yamamoto, H Motohashi, N Suzuki, Y Fujii-Kuriyama, J Mimura, C Tohyama, K Nohara. A constitutively active aryl hydrocarbon receptor induces growth inhibition by cell cycle arrest and apoptosis in Jurkat T cells. TOXICOLOGICAL SCIENCES. 2003. 72. 367-367
  • M Tabuchi, K Umegaki, T Ito, A Suzuki, Tomita, I, M Ikeda, T Tomita. Elevation of serum NOx concentration with a concomitant rise in heart rates at onset of stroke in spontaneous stroke medal rats (M-SHRSP). STROKE. 2000. 31. 11. 2866-2867
所属学会 (2件):
日本分子生物学会 ,  日本薬学会
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