文献

J-GLOBAL ID：201902270401378728   整理番号：19A1629803

リンパ節郭清における非コンプライアンスは根治的胃切除術を受けた胃癌患者の腫瘍学的有効性に影響するか?【JST・京大機械翻訳】

Does Noncompliance in Lymph Node Dissection Affect Oncological Efficacy in Gastric Cancer Patients Undergoing Radical Gastrectomy?

著者 (60件)： Chen Qi-Yue (Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian Province, China) ,  Chen Qi-Yue (Department of General Surgery, Fujian Medical University Union Hospital, Fuzhou, China) ,  Chen Qi-Yue (Key Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China) ,  Chen Qi-Yue (Fujian Key Laboratory of Tumor Microbiology, Fujian Medical University, Fuzhou, China) ,  Zhong Qing (Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian Province, China) ,  Zhong Qing (Department of General Surgery, Fujian Medical University Union Hospital, Fuzhou, China) ,  Zhong Qing (Key Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China) ,  Zhong Qing (Fujian Key Laboratory of Tumor Microbiology, Fujian Medical University, Fuzhou, China) ,  Liu Zhi-Yu (Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian Province, China) ,  Liu Zhi-Yu (Department of General Surgery, Fujian Medical University Union Hospital, Fuzhou, China) ,  Liu Zhi-Yu (Key Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China) ,  Liu Zhi-Yu (Fujian Key Laboratory of Tumor Microbiology, Fujian Medical University, Fuzhou, China) ,  Xie Jian-Wei (Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian Province, China) ,  Xie Jian-Wei (Department of General Surgery, Fujian Medical University Union Hospital, Fuzhou, China) ,  Xie Jian-Wei (Key Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China) ,  Xie Jian-Wei (Fujian Key Laboratory of Tumor Microbiology, Fujian Medical University, Fuzhou, China) ,  Wang Jia-Bin (Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian Province, China) ,  Wang Jia-Bin (Department of General Surgery, Fujian Medical University Union Hospital, Fuzhou, China) ,  Wang Jia-Bin (Key Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China) ,  Wang Jia-Bin (Fujian Key Laboratory of Tumor Microbiology, Fujian Medical University, Fuzhou, China) ,  Lin Jian-Xian (Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian Province, China) ,  Lin Jian-Xian (Department of General Surgery, Fujian Medical University Union Hospital, Fuzhou, China) ,  Lin Jian-Xian (Key Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China) ,  Lin Jian-Xian (Fujian Key Laboratory of Tumor Microbiology, Fujian Medical University, Fuzhou, China) ,  Lu Jun (Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian Province, China) ,  Lu Jun (Department of General Surgery, Fujian Medical University Union Hospital, Fuzhou, China) ,  Lu Jun (Key Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China) ,  Lu Jun (Fujian Key Laboratory of Tumor Microbiology, Fujian Medical University, Fuzhou, China) ,  Cao Long-Long (Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian Province, China) ,  Cao Long-Long (Department of General Surgery, Fujian Medical University Union Hospital, Fuzhou, China) ,  Cao Long-Long (Key Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China) ,  Cao Long-Long (Fujian Key Laboratory of Tumor Microbiology, Fujian Medical University, Fuzhou, China) ,  Lin Mi (Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian Province, China) ,  Lin Mi (Department of General Surgery, Fujian Medical University Union Hospital, Fuzhou, China) ,  Lin Mi (Key Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China) ,  Lin Mi (Fujian Key Laboratory of Tumor Microbiology, Fujian Medical University, Fuzhou, China) ,  Tu Ru-Hong (Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian Province, China) ,  Tu Ru-Hong (Department of General Surgery, Fujian Medical University Union Hospital, Fuzhou, China) ,  Tu Ru-Hong (Key Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China) ,  Tu Ru-Hong (Fujian Key Laboratory of Tumor Microbiology, Fujian Medical University, Fuzhou, China) ,  Huang Ze-Ning (Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian Province, China) ,  Huang Ze-Ning (Department of General Surgery, Fujian Medical University Union Hospital, Fuzhou, China) ,  Huang Ze-Ning (Key Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China) ,  Huang Ze-Ning (Fujian Key Laboratory of Tumor Microbiology, Fujian Medical University, Fuzhou, China) ,  Lin Ju-Li (Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian Province, China) ,  Lin Ju-Li (Department of General Surgery, Fujian Medical University Union Hospital, Fuzhou, China) ,  Lin Ju-Li (Key Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China) ,  Lin Ju-Li (Fujian Key Laboratory of Tumor Microbiology, Fujian Medical University, Fuzhou, China) ,  Li Ping (Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian Province, China) ,  Li Ping (Department of General Surgery, Fujian Medical University Union Hospital, Fuzhou, China) ,  Li Ping (Key Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China) ,  Li Ping (Fujian Key Laboratory of Tumor Microbiology, Fujian Medical University, Fuzhou, China) ,  Zheng Chao-Hui (Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian Province, China) ,  Zheng Chao-Hui (Department of General Surgery, Fujian Medical University Union Hospital, Fuzhou, China) ,  Zheng Chao-Hui (Key Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China) ,  Zheng Chao-Hui (Fujian Key Laboratory of Tumor Microbiology, Fujian Medical University, Fuzhou, China) ,  Huang Chang-Ming (Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian Province, China) ,  Huang Chang-Ming (Department of General Surgery, Fujian Medical University Union Hospital, Fuzhou, China) ,  Huang Chang-Ming (Key Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China) ,  Huang Chang-Ming (Fujian Key Laboratory of Tumor Microbiology, Fujian Medical University, Fuzhou, China)
資料名： Annals of Surgical Oncology  (Annals of Surgical Oncology)
巻： 26  号： 6  ページ： 1759-1771  発行年： 2019年 
JST資料番号： W1826A  ISSN： 1068-9265  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： ドイツ (DEU)  言語： 英語 (EN)

抄録/ポイント： 非準拠アントD2リンパ節郭清患者に対する治療の予後を検討した報告は少ない。根治的胃切除後の胃癌(GC)患者における長期生存に対するリンパ節(LN)解離における非コンプライアンスの影響を検討し,介入対策を検討した。臨床病理学的データは,GCのために根治的胃切除を受けた201人の患者で遡及的に分析された。非コンプライアンスは,日本のGC協会のプロトコルで記述されるように,1個以上の空のLNステーションを有する患者と定義された。全体の非コンプライアンス率は49.1%であった。3年全生存率(OS)率は非準拠アント患者よりも有意に良好であった(74.0%対60.1%,P<0.001)。単変量および多変量解析は,非コンプライアンスがOSの独立危険因子であることを明らかにした。ロジスティック回帰分析により,胃切除の程度,原発腫瘍部位,腹腔内手術の歴史,ボディマスインデックス,および胃切除は非コンプライアンスに対する独立した術前予測因子であることが示された。Cox分析は,年齢,pT,pN,および胃切除の程度が,非準拠アントリンパ節切除患者におけるOSに独立に影響することを示した。しかしながら,OSは,化学療法に対する推奨に関わらず,非適合群よりも有意に良好であった。化学療法が推奨されなかった化学療法およびステージII患者(pT1N2/N3M0およびpT3N0M0)の患者よりも化学療法患者においてOSが有意に良好であることを層別解析が示した。非コンプライアンスは,GCに対する根治的胃切除後の独立危険因子である。補助化学療法はpT1N2/N3M0およびpT3N0M0疾患患者の予後を改善した。Copyright 2019 Society of Surgical Oncology Translated from English into Japanese by JST.【JST・京大機械翻訳】

シソーラス用語： 予後 ,  腹腔 ,  *胃切除 ,  多変量解析 ,  *有効性 ,  ボディマスインデックス ,  層別 ,  薬物療法 ,  危険因子 ,  *リンパ節郭清 ,  *リンパ節 ,  *胃腫瘍
準シソーラス用語： 予測因子 ,  3年全生存率 ,  長期生存 , 【Automatic Indexing@JST】

分類 (4件)： 腫ようの外科療法  (GE03033T) ,  腫ようの化学・生化学・病理学  (GE02030N) ,  遺伝子発現  (EC02040Q) ,  消化器の腫よう  (GH04000D)

タイトルに関連する用語 (7件)： リンパ節郭清 ,  コンプライアンス ,  胃切除術 ,  胃 ,  癌患者 ,  腫瘍学 ,  有効性