文献

J-GLOBAL ID：201902289463961784   整理番号：19A0791524

ステージIII粘液性および漿液性卵巣癌の比較:症例対照研究【JST・京大機械翻訳】

Comparison of stage III mucinous and serous ovarian cancer: a case-control study

著者 (14件)： Cuylan Zeliha Firat (Department of Gynecologic Oncology, Zekai Tahir Burak Women’s Health Training and Research Hospital, Faculty of Medicine, University of Health Sciences, Ankara, Turkey) ,  Karabuk Emine (Faculty of Health Sciences, Department of Obstetrics and Gynecology, Acibadem University, Istanbul, Turkey) ,  OZ Murat (Department of Gynecologic Oncology, Zekai Tahir Burak Women’s Health Training and Research Hospital, Faculty of Medicine, University of Health Sciences, Ankara, Turkey) ,  Turan Ahmet Taner (Department of Gynecologic Oncology, Etlik Zubeyde Hanim Women’s Health Training and Research Hospital, Faculty of Medicine, University of Health Sciences, Ankara, Turkey) ,  Meydanli Mehmet M. (Department of Gynecologic Oncology, Zekai Tahir Burak Women’s Health Training and Research Hospital, Faculty of Medicine, University of Health Sciences, Ankara, Turkey) ,  Taskin Salih (Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, School of Medicine, AnkaraUniversity, Ankara, Turkey) ,  Sari Mustafa Erkan (Department of Gynecologic Oncology, Zekai Tahir Burak Women’s Health Training and Research Hospital, Faculty of Medicine, University of Health Sciences, Ankara, Turkey) ,  Sahin Hanifi (Department of Gynecologic Oncology, Zekai Tahir Burak Women’s Health Training and Research Hospital, Faculty of Medicine, University of Health Sciences, Ankara, Turkey) ,  Ulukent Suat C. (Department of General Surgery, Kanuni Sultan Suleyman Teaching and Research Hospital, Faculty of Medicine, University of Health Sciences, Istanbul, Turkey) ,  Akbayir Ozgur (Department of Gynecologic Oncology, Kanuni Sultan Suleyman Teaching and Research Hospital, Faculty of Medicine, University of Health Sciences, Istanbul, Turkey) ,  Gungorduk Kemal (Department of Gynecologic Oncology, Tepecik Education and Research Hospital, Faculty of Medicine, University of Health Sciences, Izmir, Turkey) ,  Gungor Tayfun (Department of Gynecologic Oncology, Zekai Tahir Burak Women’s Health Training and Research Hospital, Faculty of Medicine, University of Health Sciences, Ankara, Turkey) ,  Kose Mehmet F. (Faculty of Health Sciences, Department of Obstetrics and Gynecology, Acibadem University, Istanbul, Turkey) ,  Ayhan Ali (Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Faculty of Medicine, BaskentUniversity, Ankara, Turkey)
資料名： Journal of Ovarian Research (Web)  (Journal of Ovarian Research (Web))
巻： 11  号： 1  ページ： 91  発行年： 2018年 
JST資料番号： U7521A  ISSN： 1757-2215  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： イギリス (GBR)  言語： 英語 (EN)

抄録/ポイント： 本症例対照研究の目的は,最大または最適な細胞減少を受けたステージIII粘液性卵巣癌(MOC)と女性の予後を比較することであり,同様の方法で治療されたステージIII漿液性上皮性卵巣癌(EOC)の女性のそれらに対してパクリタキセル+カルボプラチン化学療法を行った。トルコの7つの婦人科腫瘍部門でステージIII MOC患者を同定するために,多施設,遡及的レビューを行った。MOCの81人の女性が含まれた。各症例は,年齢,腫瘍グレード,疾患の病期,および残存疾患の程度に関して,ステージIII漿液性EOCを有する2人の女性と一致した。生存推定値は,Kaplan-Meierプロットを用いて測定した。結果を予測する変数をCox回帰モデルを用いて分析した。54か月の追跡期間の中央値により,ステージIII MOCを有する女性に対する中央値無進行生存(PFS)は,しょう液群(p=0.19)において29.0か月(95%CI;24.04~33.95,SE:2.52)と比較して18.0か月(95%CI;13.8~22.1,SE:2.13)であった。MOC群の5年全生存率は,漿液性EOC群のそれより有意に低かった(それぞれ44.9%対66.3%;p<0.001)。全コホートに対して,複数の腹膜インプラント(Hazard比[HR]2.39;95%信頼区間[CI],1.38~4.14,p=0.002)および粘液組織学(HR2.28;95%CI,1.53~3.40,p<0.001)の存在が,減少したOSの独立予測因子として同定された。MOCを有する患者は,漿液性EOCを有する女性と比較して,それらの腫瘍の死亡の2.3倍の可能性があると思われる。Copyright 2019 The Author(s) All rights reserved. Translated from English into Japanese by JST.【JST・京大機械翻訳】

シソーラス用語： トルコ共和国 ,  信頼区間 ,  カルボプラチン ,  *卵巣腫瘍 ,  推定量 ,  母集団 ,  予後 ,  腫瘍 ,  *粘液 ,  ヒト ,  回帰モデル ,  女性 ,  薬物療法 ,  *症例報告
準シソーラス用語： 予測因子 ,  5年全生存率 ,  病期 , 【Automatic Indexing@JST】

著者キーワード (4件)： 生存の分析 ,  上皮性卵巣癌 ,  粘液腺癌 ,  漿液性嚢胞腺癌

分類 (2件)： 腫ようの化学・生化学・病理学  (GE02030N) ,  女性生殖器と胎児の腫よう  (GS04000K)

引用文献 (27件)：

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タイトルに関連する用語 (4件)： ステージ ,  粘液性 ,  漿液性卵巣癌 ,  症例対照研究