磯野蒼

イソノアオイ | Isono Aoi

所属機関・部署：
職名：助教

研究分野 (2件)：有機合成化学 , 薬系化学、創薬科学

研究キーワード (4件)：膜透過性ペプチド , ホウ素中性子捕捉療法(BNCT) , ドラッグデリバリーシステム(DDS) , ペプチド合成

競争的資金等の研究課題 (2件)：

論文 (3件)：

Aoi Isono, Mieko Tsuji, Yu Sanada, Akari Matsushita, Shinichiro Masunaga, Tasuku Hirayama, Hideko Nagasawa. Design, Synthesis, and Evaluation of Lipopeptide Conjugates of Mercaptoundecahydrododecaborate for Boron Neutron Capture Therapy. ChemMedChem. 2019. 14. 8. 823-832
Takahiko Imai, Keisuke Mishiro, Toshinori Takagi, Aoi Isono, Hideko Nagasawa, Kazuhiro Tsuruma, Masamitsu Shimazawa, Hideaki Hara. Protective Effect of Bendavia (SS-31) Against Oxygen/Glucose-Deprivation Stress-Induced Mitochondrial Damage in Human Brain Microvascular Endothelial Cells. Current neurovascular research. 2017. 14. 1. 53-59
Mieko Tsuji, Satoshi Ueda, Tasuku Hirayama, Kensuke Okuda, Yoshiaki Sakaguchi, Aoi Isono, Hideko Nagasawa. FRET-based imaging of transbilayer movement of pepducin in living cells by novel intracellular bioreductively activatable fluorescent probes. Organic & biomolecular chemistry. 2013. 11. 18. 3030-7

MISC (2件)：

Isono A, Okuda K, Hirayama T, Masunaga S, Nagasawa H. Development of Nuder-targeting Boron Carriers Based on the Chemistry of Direct Cell-penetrating Pepducins. Progress Report 2014, The Research Reactor Institute, Kyoto University. 2015. 5
Isono A, Okuda K, Hirayama T, Masunaga S, Nagasawa H. Design and Synthesis of a New Membrane Peameable Boron Carrier Using the Lipidated Peptide Vehicle. Progress Report 2013, The Research Reactor Institute, Kyoto University. 2014. 121

講演・口頭発表等 (8件)：

Desing and synthesis of new membrane permeable boron carriers for BNCT based on pepducin technology
(9th Young Researchers' BNCT Meeting 2017)
Pepducinを基盤とするホウ素捕捉療法のための膜透過性ホウ素キャリアの開発
(第35回メディシナルケミストリーシンポジウム 2017)
ホウ素中性子捕捉療法のためのペプデュシンを基盤とする膜透過性ホウ素キャリアの開発
(日本薬学会第136年会 2016)
Design and synthesis of new boron carriers based on pepducin chemistry and evaluation of their subcellular distribution
(The 2015 International Chemical Congress of Pacific Basin Societies (Pacifichem 2015) 2015)
Design, synthesis and fluorescence imaging of new membrane permeable boron carrier based on the pepducin chemistry
(15th International Congress of Radiation Research (ICRR) 2015)

学位 (1件)：

経歴 (1件)：

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磯野 蒼