文献

J-GLOBAL ID：202002228503683392   整理番号：20A1679411

COVID-19:ヒトでのSARS-CoV-2セロコンバージョンを検出する血清学的測定法

A serological assay to detect SARS-CoV-2 seroconversion in humans

著者 (49件)： AMANAT Fatima (Dep. of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA) ,  STADLBAUER Daniel (Dep. of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA) ,  STROHMEIER Shirin (Dep. of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA) ,  CHROMIKOVA Veronika (Dep. of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA) ,  MCMAHON Meagan (Dep. of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA) ,  JIANG Kaijun (Dep. of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA) ,  ARUNKUMAR Guha Asthagiri (Dep. of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA) ,  JURCZYSZAK Denise (Dep. of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA) ,  POLANCO Jose (Dep. of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA) ,  BERMUDEZ-GONZALEZ Maria (Dep. of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA) ,  KLEINER Giulio (Dep. of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA) ,  AYDILLO Teresa (Dep. of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA) ,  MIORIN Lisa (Dep. of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA) ,  LIU Sean T. H. (Dep. of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA) ,  MORAN Thomas (Dep. of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA) ,  GARCIA-SASTRE Adolfo (Dep. of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA) ,  SIMON Viviana (Dep. of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA) ,  KRAMMER Florian (Dep. of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA) ,  AMANAT Fatima (Graduate School of Biomedical Sci., Icahn School of Medicine at Mount Sinai, New York, NY, USA) ,  ARUNKUMAR Guha Asthagiri (Graduate School of Biomedical Sci., Icahn School of Medicine at Mount Sinai, New York, NY, USA) ,  JURCZYSZAK Denise (Graduate School of Biomedical Sci., Icahn School of Medicine at Mount Sinai, New York, NY, USA) ,  STROHMEIER Shirin (Dep. of Biotechnology, Univ. Natural Resources and Life Sci., Vienna, AUT) ,  NGUYEN Thi H. O. (Dep. of Microbiology and Immunology, Peter Doherty Inst. for Infection and Immunity, Univ. Melbourne, Melbourne, Victoria, AUS) ,  KEDZIERSKA Katherine (Dep. of Microbiology and Immunology, Peter Doherty Inst. for Infection and Immunity, Univ. Melbourne, Melbourne, Victoria, AUS) ,  POLANCO Jose (Dep. of Genetics and Genomic Sci., Icahn School of Medicine at Mount Sinai, New York, NY, USA) ,  AYDILLO Teresa (Global Health and Emerging Pathogens Inst., Icahn School of Medicine at Mount Sinai, New York, NY, USA) ,  MIORIN Lisa (Global Health and Emerging Pathogens Inst., Icahn School of Medicine at Mount Sinai, New York, NY, USA) ,  GARCIA-SASTRE Adolfo (Global Health and Emerging Pathogens Inst., Icahn School of Medicine at Mount Sinai, New York, NY, USA) ,  SIMON Viviana (Global Health and Emerging Pathogens Inst., Icahn School of Medicine at Mount Sinai, New York, NY, USA) ,  FIERER Daniel S. (Div. of Infectious Diseases, Dep. of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA) ,  LUGO Luz Amarilis (Div. of Infectious Diseases, Dep. of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA) ,  KOJIC Erna Milunka (Div. of Infectious Diseases, Dep. of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA) ,  LIU Sean T. H. (Div. of Infectious Diseases, Dep. of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA) ,  GARCIA-SASTRE Adolfo (Div. of Infectious Diseases, Dep. of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA) ,  SIMON Viviana (Div. of Infectious Diseases, Dep. of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA) ,  STOEVER Jonathan (Div. of Pulmonary, Critical Care, and Sleep Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA) ,  LIU Sean T. H. (Dep. of Medicine, Mount Sinai Queens, Astoria, NY, USA) ,  LIU Sean T. H. (Div. of Hospital Medicine, Mount Sinai Health System, New York, NY, USA) ,  CUNNINGHAM-RUNDLES Charlotte (Div. of Clinical Immunology, Dep. of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA) ,  CUNNINGHAM-RUNDLES Charlotte (Dep. of Pediatrics, the Icahn School of Medicine at Mount Sinai, NY, USA) ,  FELGNER Philip L. (Dep. of Physiology and Biophysics, Univ. California, Irvine, Irvine, CA, USA) ,  GARCIA-SASTRE Adolfo (Tisch Cancer Inst., Icahn School of Medicine at Mount Sinai, New York, NY, USA) ,  CAPLIVSKI Daniel (Travel Medicine Program, Div. of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, NY, USA) ,  CHENG Allen C. (School of Public Health and Preventive Medicine, Monash Univ. and Infection Prevention and Healthcare Epidemiology Unit Alfred Health, Melbourne, Victoria, AUS) ,  VAPALAHTI Olli (Dep. of Virology, Medicum, Univ. Helsinki, Helsinki, FIN) ,  HEPOJOKI Jussi M. (Dep. of Virology, Medicum, Univ. Helsinki, Helsinki, FIN) ,  VAPALAHTI Olli (Veterinary Biosciences, Veterinary Fac., Univ. Helsinki, Helsinki, FIN) ,  VAPALAHTI Olli (Dep. of Virology and Immunology, Helsinki Univ. Hospital (HUSLAB), Helsinki, FIN) ,  HEPOJOKI Jussi M. (Inst. of Veterinary Pathology, Vetsuisse Fac., Univ. Zuerich, Zuerich, CHE)
資料名： Nature Medicine  (Nature Medicine)
巻： 26  号： 7  ページ： 1033-1036  発行年： 2020年07月 
JST資料番号： W0636A  ISSN： 1078-8956  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： アメリカ合衆国 (USA)  言語： 英語 (EN)

抄録/ポイント： 本論文では,ヒトでSARS-CoV-2セロコンバージョンを引き起こした物質のスクリーニングと特定のためのELISA(enzyme-linked immunosorbent assay)について報告する。この測定法は,感染性のウイルスを扱う必要がなく,血清や血漿に含まれる多様な抗体タイプを検出するように調整することができ,またスケーリング可能である。血清学的測定法は,集団中で以前に起こったSARS-CoV-2への曝露や回復期患者の血漿治療のための反応性の高いヒトドナーの特定,また予防との関連の調査に役立つ極めて重要なものである。Copyright Nature Japan KK 2020

シソーラス用語： ドナー ,  血漿 ,  *血清 ,  抗体 ,  ヒト ,  回復期
準シソーラス用語： *SARSウイルス ,  *血清学 ,  *セロコンバージョン ,  感染性 , 【Automatic Indexing@JST】

分類 (2件)： 感染症・寄生虫症一般  (GD01010H) ,  細胞膜の受容体  (EF04030C)

タイトルに関連する用語 (6件)： COVID-19 ,  ヒト ,  SARS-CoV-2 ,  セロコンバージョン ,  血清学 ,  測定法