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J-GLOBAL ID：202002245703055986   整理番号：20A0796083

不整脈性右室心筋症患者における心外膜アブレーションの必要性予測における非侵襲的信号平均心電図解析の応用【JST・京大機械翻訳】

Application of noninvasive signal-averaged electrocardiogram analysis in predicting the requirement of epicardial ablation in patients with arrhythmogenic right ventricular cardiomyopathy

著者 (39件)： Chung Fa-Po (Heart Rhythm Center, Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan) ,  Chung Fa-Po (Institute of Clinical Medicine and Department of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan) ,  Lin Chin-Yu (Heart Rhythm Center, Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan) ,  Lin Chin-Yu (Institute of Clinical Medicine and Department of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan) ,  Lin Yenn-Jiang (Heart Rhythm Center, Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan) ,  Lin Yenn-Jiang (Institute of Clinical Medicine and Department of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan) ,  Chang Shih-Lin (Heart Rhythm Center, Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan) ,  Chang Shih-Lin (Institute of Clinical Medicine and Department of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan) ,  Lo Li-Wei (Heart Rhythm Center, Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan) ,  Lo Li-Wei (Institute of Clinical Medicine and Department of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan) ,  Hu Yu-Feng (Heart Rhythm Center, Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan) ,  Hu Yu-Feng (Institute of Clinical Medicine and Department of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan) ,  Tuan Ta-Chuan (Heart Rhythm Center, Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan) ,  Tuan Ta-Chuan (Institute of Clinical Medicine and Department of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan) ,  Chao Tze-Fan (Heart Rhythm Center, Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan) ,  Chao Tze-Fan (Institute of Clinical Medicine and Department of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan) ,  Liao Jo-Nan (Heart Rhythm Center, Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan) ,  Liao Jo-Nan (Institute of Clinical Medicine and Department of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan) ,  Chang Ting-Yung (Heart Rhythm Center, Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan) ,  Chang Ting-Yung (Institute of Clinical Medicine and Department of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan) ,  Tan Vern Hsen (Heart Rhythm Center, Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan) ,  Kuo Ling (Heart Rhythm Center, Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan) ,  Kuo Ling (Institute of Clinical Medicine and Department of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan) ,  Wu Cheng-I (Heart Rhythm Center, Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan) ,  Wu Cheng-I (Institute of Clinical Medicine and Department of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan) ,  Liu Chih-Min (Heart Rhythm Center, Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan) ,  Liu Chih-Min (Institute of Clinical Medicine and Department of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan) ,  Vicera Jennifer Jeanne B. (Heart Rhythm Center, Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan) ,  Chen Chun-Chao (Heart Rhythm Center, Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan) ,  Chin Chye-Gen (Heart Rhythm Center, Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan) ,  Liu Shin-Huei (Heart Rhythm Center, Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan) ,  Liu Shin-Huei (Institute of Clinical Medicine and Department of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan) ,  Cheng Wen-Han (Heart Rhythm Center, Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan) ,  Cheng Wen-Han (Institute of Clinical Medicine and Department of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan) ,  Chou Ching-Yao (Heart Rhythm Center, Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan) ,  Lugtu Isaiah C. (Heart Rhythm Center, Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan) ,  Liu Ching-Han (Heart Rhythm Center, Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan) ,  Chen Shih-Ann (Heart Rhythm Center, Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan) ,  Chen Shih-Ann (Institute of Clinical Medicine and Department of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan)
資料名： Heart Rhythm  (Heart Rhythm)
巻： 17  号： 4  ページ： 584-591  発行年： 2020年 
JST資料番号： W3164A  ISSN： 1547-5271  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： オランダ (NLD)  言語： 英語 (EN)

抄録/ポイント： 信号平均心電図(SAECG)は,診断情報だけでなく,不整脈性右室心筋症(ARVC)におけるアブレーションの予後的意味も提供する。本研究は,ARVCにおける心外膜アプローチを必要とする不整脈原性基質の同定におけるSAECGの役割を検証することを目的とした。薬剤不応性心室性不整脈に対して成功したアブレーションを受けたARVCの確定診断を有する91名の患者を登録し,2群に分類した。1群は心内膜のみで成功したアブレーションを受け,2群は追加の心外膜アプローチを必要とする成功したアブレーションを受けた。患者とSAECGパラメータのベースライン特性を分析のために得た。2群において,男性の優位性,より悪い右室(RV)機能,失神のより高い発生率,および脱分極異常が観察された。さらに,異常SAECG基準の数は,群1より群2で高かった。多変量解析の後,心外膜アブレーションの必要条件の独立予測因子は,異常SAECG基準の数(オッズ比2.8,95%信頼区間1.4~5.4;P=0.003)と失神の存在(オッズ比11.7;95%信頼区間2.7~50.4;P=0.001)を含んだ。加えて,≧2異常SAECG基準は,より大きいRV心内膜単極低電圧帯(P<0.001),より大きいRV心内膜/心外膜双極低電圧帯/瘢痕(P<0.05)およびより長いRV心内膜/心外膜総活性化時間(それぞれP<0.001およびP=0.004)と関連した。異常なSAECG基準の数は,罹患した心外膜基質の範囲と相関し,ARVC患者における心外膜アブレーションの必要性を予測するための潜在的な代理マーカーである可能性がある。Copyright 2020 Elsevier B.V., Amsterdam. All rights reserved. Translated from English into Japanese by JST.【JST・京大機械翻訳】

シソーラス用語： 多変量解析 ,  *心電図 ,  基質 ,  脱分極 ,  *不整脈 ,  予後 ,  *アブレーション ,  心内膜 ,  瘢痕 ,  *心筋症 ,  *心外膜 ,  失神
準シソーラス用語： 心室性不整脈 ,  *右心室 ,  予測因子 , 【Automatic Indexing@JST】

著者キーワード (5件)： 不整脈性右室心筋症 ,  心外膜アプローチ ,  心外膜基質 ,  信号平均ECG ,  心室性不整脈

分類 (1件)： 循環系の疾患  (GJ03000C)

タイトルに関連する用語 (10件)： 不整脈 ,  右室 ,  心筋症 ,  患者 ,  心外膜アブレーション ,  予測 ,  非侵襲的 ,  平均 ,  心電図解析 ,  応用