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J-GLOBAL ID：202002253264689740   整理番号：20A1203444

健常および慢性疾患高齢者における筋肉および脂肪に対する長期強度トレーニングの影響【JST・京大機械翻訳】

The influence of prolonged strength training upon muscle and fat in healthy and chronically diseased older adults

著者 (38件)： Gylling Anne Theil (Institute of Sports Medicine Copenhagen, Department of Orthopaedic Surgery M81 and Centre for Translational Research, Bispebjerg and Frederiksberg Hospital, Bispebjerg Bakke 23, 2400 Copenhagen, NV, Denmark) ,  Gylling Anne Theil (Center for Healthy Aging, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen, N, Denmark) ,  Eriksen Christian Skou (Institute of Sports Medicine Copenhagen, Department of Orthopaedic Surgery M81 and Centre for Translational Research, Bispebjerg and Frederiksberg Hospital, Bispebjerg Bakke 23, 2400 Copenhagen, NV, Denmark) ,  Eriksen Christian Skou (Center for Healthy Aging, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen, N, Denmark) ,  Garde Ellen (Center for Healthy Aging, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen, N, Denmark) ,  Garde Ellen (Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hvidovre Hospital, Kettegaard Alle 30, DK-2650 Hvidovre, Denmark) ,  Garde Ellen (Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Oster Farimagsgade 5A, 1353 Copenhagen K, Denmark) ,  Wimmelmann Cathrine Lawaetz (Center for Healthy Aging, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen, N, Denmark) ,  Wimmelmann Cathrine Lawaetz (Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Oster Farimagsgade 5A, 1353 Copenhagen K, Denmark) ,  Reislev Nina Linde (Center for Healthy Aging, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen, N, Denmark) ,  Reislev Nina Linde (Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hvidovre Hospital, Kettegaard Alle 30, DK-2650 Hvidovre, Denmark) ,  Bieler Theresa (Institute of Sports Medicine Copenhagen, Department of Orthopaedic Surgery M81 and Centre for Translational Research, Bispebjerg and Frederiksberg Hospital, Bispebjerg Bakke 23, 2400 Copenhagen, NV, Denmark) ,  Bieler Theresa (Center for Healthy Aging, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen, N, Denmark) ,  Bieler Theresa (Department of Physical and Occupational Therapy, Bispebjerg and Frederiksberg Hospital, Bispebjerg Bakke 23, 2400 Copenhagen, NV, Denmark) ,  Ziegler Andreas Kraag (Institute of Sports Medicine Copenhagen, Department of Orthopaedic Surgery M81 and Centre for Translational Research, Bispebjerg and Frederiksberg Hospital, Bispebjerg Bakke 23, 2400 Copenhagen, NV, Denmark) ,  Ziegler Andreas Kraag (Center for Healthy Aging, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen, N, Denmark) ,  Andersen Kasper Winther (Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hvidovre Hospital, Kettegaard Alle 30, DK-2650 Hvidovre, Denmark) ,  Bauer Christian (Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hvidovre Hospital, Kettegaard Alle 30, DK-2650 Hvidovre, Denmark) ,  Bauer Christian (Department of Technology, University College Copenhagen, Sigurdsgade 26, 2200 Copenhagen N, Denmark) ,  Dideriksen Kasper (Institute of Sports Medicine Copenhagen, Department of Orthopaedic Surgery M81 and Centre for Translational Research, Bispebjerg and Frederiksberg Hospital, Bispebjerg Bakke 23, 2400 Copenhagen, NV, Denmark) ,  Dideriksen Kasper (Center for Healthy Aging, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen, N, Denmark) ,  Baekgaard Maria (Institute of Sports Medicine Copenhagen, Department of Orthopaedic Surgery M81 and Centre for Translational Research, Bispebjerg and Frederiksberg Hospital, Bispebjerg Bakke 23, 2400 Copenhagen, NV, Denmark) ,  Baekgaard Maria (Center for Healthy Aging, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen, N, Denmark) ,  Mertz Kenneth Hudlebusch (Institute of Sports Medicine Copenhagen, Department of Orthopaedic Surgery M81 and Centre for Translational Research, Bispebjerg and Frederiksberg Hospital, Bispebjerg Bakke 23, 2400 Copenhagen, NV, Denmark) ,  Mertz Kenneth Hudlebusch (Center for Healthy Aging, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen, N, Denmark) ,  Bayer Monika Lucia (Institute of Sports Medicine Copenhagen, Department of Orthopaedic Surgery M81 and Centre for Translational Research, Bispebjerg and Frederiksberg Hospital, Bispebjerg Bakke 23, 2400 Copenhagen, NV, Denmark) ,  Bayer Monika Lucia (Center for Healthy Aging, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen, N, Denmark) ,  Bloch-Ibenfeldt Mads (Institute of Sports Medicine Copenhagen, Department of Orthopaedic Surgery M81 and Centre for Translational Research, Bispebjerg and Frederiksberg Hospital, Bispebjerg Bakke 23, 2400 Copenhagen, NV, Denmark) ,  Bloch-Ibenfeldt Mads (Center for Healthy Aging, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen, N, Denmark) ,  Boraxbekk Carl-Johan (Institute of Sports Medicine Copenhagen, Department of Orthopaedic Surgery M81 and Centre for Translational Research, Bispebjerg and Frederiksberg Hospital, Bispebjerg Bakke 23, 2400 Copenhagen, NV, Denmark) ,  Boraxbekk Carl-Johan (Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hvidovre Hospital, Kettegaard Alle 30, DK-2650 Hvidovre, Denmark) ,  Boraxbekk Carl-Johan (Department of Radiation Sciences, Umea University, S-901 87 Umea, Sweden) ,  Siebner Hartwig Roman (Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hvidovre Hospital, Kettegaard Alle 30, DK-2650 Hvidovre, Denmark) ,  Siebner Hartwig Roman (Department of Neurology, Bispebjerg and Frederiksberg Hospital, Bispebjerg Bakke 23, 2400 Copenhagen, NV, Denmark) ,  Mortensen Erik Lykke (Center for Healthy Aging, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen, N, Denmark) ,  Mortensen Erik Lykke (Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Oster Farimagsgade 5A, 1353 Copenhagen K, Denmark) ,  Kjaer Michael (Institute of Sports Medicine Copenhagen, Department of Orthopaedic Surgery M81 and Centre for Translational Research, Bispebjerg and Frederiksberg Hospital, Bispebjerg Bakke 23, 2400 Copenhagen, NV, Denmark) ,  Kjaer Michael (Center for Healthy Aging, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen, N, Denmark)
資料名： Experimental Gerontology  (Experimental Gerontology)
巻： 136  ページ： Null  発行年： 2020年 
JST資料番号： T0267A  ISSN： 0531-5565  CODEN： EXGEAB  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： オランダ (NLD)  言語： 英語 (EN)

抄録/ポイント： 身体的筋肉機能と脳海馬サイズは年齢とともに減少し,60歳後に加速した。数か月にわたる強度訓練は身体機能を改善するが,長期強度訓練が身体機能と海馬容積にどのように影響するかについてはほとんど知られていない。したがって,著者らは,反復年齢個人における筋肉量,機能および海馬容積に及ぼす2つの異なる強度の1年強度訓練の効果を調査することを目的とした。この集学的無作為化比較試験(臨床試験:gov:NCT02123641)において,参加者を,教師つき,重い抵抗訓練(HRT,n=149,3/週),b)中等度強度抵抗訓練(MIT,n=154,3/週)またはc)非運動活動(CON,n=148)に割り当てた。451名の参加者が無作為化された(62~70歳,女性61%,慢性医学疾患を伴う約80%),および419名が治療-治療分析(n=143,144および132;HRT,MITおよびCON)に含まれた。筋力(一次転帰),強度およびサイズ,身体機能,身体組成,海馬容積および身体的/精神的幸福の変化を分析した。参加者(HRT+MIT)の83%が少なくとも2/週で訓練を完了した。下肢伸筋力は全群で変化しなかったが,強度訓練は両群で等尺性膝伸筋強度に正の効果を示したが,筋肉量の増加,外側広筋の断面積,全身脂肪率の低下,内臓脂肪量および改善された精神衛生(SF-36)がHRTのみで生じた。さらに,すべての群において,椅子スタンドの性能は改善されたが,海馬容積は,強度訓練の影響なしで,すべての群において時間とともに減少した。これらの結果は,下肢伸筋力が長期の教師つき強度訓練に応答しないが,健康で慢性的に罹患した高齢者の混合群におけるこのタイプの訓練は,良好なコンプライアンスで実行でき,筋力,筋肉量および腹部脂肪の生理学的パラメータの一貫した変化を誘導することを示す。Copyright 2020 Elsevier B.V., Amsterdam. All rights reserved. Translated from English into Japanese by JST.【JST・京大機械翻訳】

シソーラス用語： 断面積 ,  *伸筋 ,  女性 ,  海馬 ,  臨床試験 ,  精神衛生 ,  筋力 ,  ランダム化比較試験
準シソーラス用語： *慢性疾患 ,  身体機能 ,  腹部脂肪 ,  外側広筋 ,  筋肉量 ,  膝伸筋 , 【Automatic Indexing@JST】

著者キーワード (6件)： 加齢 ,  身体組成 ,  物理的機能 ,  抵抗運動 ,  身体運動 ,  Hippocampus容積

分類 (2件)： 老人医学  (GC09000X) ,  スポーツ医学  (GC11000Y)

タイトルに関連する用語 (6件)： 慢性疾患 ,  高齢者 ,  筋肉 ,  脂肪 ,  長期強度 ,  トレーニング