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J-GLOBAL ID：202002257722147909   整理番号：20A2285364

アルファヘルペスウイルスのライフサイクルにおけるVP16の役割【JST・京大機械翻訳】

The Role of VP16 in the Life Cycle of Alphaherpesviruses

著者 (63件)： Fan Dengjian (Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China) ,  Fan Dengjian (Key Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu, China) ,  Fan Dengjian (Avian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China) ,  Wang Mingshu (Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China) ,  Wang Mingshu (Key Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu, China) ,  Wang Mingshu (Avian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China) ,  Cheng Anchun (Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China) ,  Cheng Anchun (Key Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu, China) ,  Cheng Anchun (Avian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China) ,  Jia Renyong (Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China) ,  Jia Renyong (Key Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu, China) ,  Jia Renyong (Avian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China) ,  Yang Qiao (Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China) ,  Yang Qiao (Key Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu, China) ,  Yang Qiao (Avian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China) ,  Wu Ying (Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China) ,  Wu Ying (Key Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu, China) ,  Wu Ying (Avian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China) ,  Zhu Dekang (Key Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu, China) ,  Zhu Dekang (Avian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China) ,  Zhao Xinxin (Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China) ,  Zhao Xinxin (Key Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu, China) ,  Zhao Xinxin (Avian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China) ,  Chen Shun (Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China) ,  Chen Shun (Key Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu, China) ,  Chen Shun (Avian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China) ,  Liu Mafeng (Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China) ,  Liu Mafeng (Key Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu, China) ,  Liu Mafeng (Avian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China) ,  Zhang Shaqiu (Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China) ,  Zhang Shaqiu (Key Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu, China) ,  Zhang Shaqiu (Avian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China) ,  Ou Xumin (Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China) ,  Ou Xumin (Key Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu, China) ,  Ou Xumin (Avian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China) ,  Mao Sai (Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China) ,  Mao Sai (Key Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu, China) ,  Mao Sai (Avian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China) ,  Gao Qun (Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China) ,  Gao Qun (Key Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu, China) ,  Gao Qun (Avian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China) ,  Sun Di (Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China) ,  Sun Di (Key Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu, China) ,  Sun Di (Avian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China) ,  Wen Xingjian (Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China) ,  Wen Xingjian (Key Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu, China) ,  Wen Xingjian (Avian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China) ,  Liu Yunya (Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China) ,  Liu Yunya (Key Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu, China) ,  Liu Yunya (Avian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China) ,  Yu Yanling (Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China) ,  Yu Yanling (Key Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu, China) ,  Yu Yanling (Avian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China) ,  Zhang Ling (Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China) ,  Zhang Ling (Key Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu, China) ,  Zhang Ling (Avian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China) ,  Tian Bin (Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China) ,  Tian Bin (Avian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China) ,  Pan Leichang (Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China) ,  Pan Leichang (Avian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China) ,  Chen Xiaoyue (Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China) ,  Chen Xiaoyue (Key Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu, China) ,  Chen Xiaoyue (Avian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China)
資料名： Frontiers in Microbiology (Web)  (Frontiers in Microbiology (Web))
巻： 11  ページ： 1910  発行年： 2020年 
JST資料番号： U7080A  ISSN： 1664-302X  資料種別： 逐次刊行物 (A)
記事区分： 文献レビュー  発行国： スイス (CHE)  言語： 英語 (EN)

抄録/ポイント： アルファヘルペスウイルスのUL48遺伝子によりコードされた蛋白質はVP16またはα遺伝子トランス活性化因子(α-TIF)と命名された。ウイルス複製の初期段階において,VP16はウイルス即時初期遺伝子の転写を活性化できる重要なトランスアクチベータであり,ウイルス複製の後期段階で,VP16はテグメントとしてウイルス集合に関与する。このレビューは,ウイルスの即時初期遺伝子の転写を活性化するためのα-TIFとして作用するVP16の機構,ウイルス潜伏期から再活性化へのその役割,およびウイルス集合と成熟へのその効果を説明する。さらに,本レビューは,アルファヘルペスウイルスのライフサイクルおよびウイルスライフサイクルにおけるVP16の役割に関するさらなる研究のための新しい洞察を提供する。Copyright 2020 The Author(s) All rights reserved. Translated from English into Japanese by JST.【JST・京大機械翻訳】

シソーラス用語： *ライフサイクル ,  遺伝子 ,  タンパク質 ,  ウイルス複製
準シソーラス用語： トランス活性化因子 ,  ウイルス潜伏 ,  VP16 ,  初期遺伝子 ,  再活性化 , 【Automatic Indexing@JST】

著者キーワード (5件)： アルファヘルペスウイルス ,  VP16 ,  転写活性化 ,  二次包絡 ,  潜在性からの再活性化

分類 (3件)： 分子遺伝学一般  (EC02010J) ,  ウイルスの生化学  (EG04030F) ,  ウイルスの生理一般  (EG04041H)

引用文献 (156件)：

• Aguilar X., Blomberg J., Brännström K., Olofsson A., Schleucher J., Björklund S. (2014). Interaction studies of the human and Arabidopsis thaliana Med25-ACID proteins with the herpes simplex virus VP16- and plant-specific Dreb2a transcription factors. PLoS One 9:e98575. doi: 10.1371/journal.pone.0098575
• Andersen B., Rosenfeld M. G. (2001). POU domain factors in the neuroendocrine system: lessons from developmental biology provide insights into human disease. Endocr. Rev. 22 2-35. doi: 10.1210/edrv.22.1.0421
• Arii J., Kawaguchi Y. (2018). The Role of HSV glycoproteins in mediating cell entry. Adv. Exp. Med. Biol. 1045 3-21. doi: 10.1007/978-981-10-7230-7_1
• Babb R., Huang C. C., Aufiero D. J., Herr W. (2001). DNA recognition by the herpes simplex virus transactivator VP16: a novel DNA-binding structure. Mol. Cell. Biol. 21 4700-4712. doi: 10.1128/mcb.21.14.4700-4712.2001
• Bentrari F., Chantôme A., Knights A., Jeannin J. F., Pance A. (2015). Oct-2 forms a complex with Oct-1 on the iNOS promoter and represses transcription by interfering with recruitment of RNA PolII by Oct-1. Nucleic Acids Res. 43 9757-9765. doi: 10.1093/nar/gkv829

タイトルに関連する用語 (4件)： アルファヘルペスウイルス ,  ライフサイクル ,  VP16 ,  役割