文献

J-GLOBAL ID：202102226547466179   整理番号：21A0830326

気管支肺異形成関連肺高血圧症(BPD-PH)の標的化:肺血管系の発達におけるFGFシグナル伝達経路の潜在的役割【JST・京大機械翻訳】

Targeting Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension (BPD-PH): Potential Role of the FGF Signaling Pathway in the Development of the Pulmonary Vascular System

著者 (15件)： Chao Cho-Ming (Key Laboratory of Interventional Pulmonology of Zhejiang Province, Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325035, China) ,  Chao Cho-Ming (Cardio-Pulmonary Institute, Universities of Giessen and Marburg Lung Center, Member of the German Center for Lung Research, Justus-Liebig-University Giessen, 35392 Giessen, Germany) ,  Chao Cho-Ming (Department of General Pediatrics and Neonatology, Justus-Liebig-University, Feulgenstrasse 12, D-35392 Giessen, Universities of Giessen and Marburg Lung Center, German Center for Lung Research, 35392 Giessen, Germany) ,  Chong Lei (Institute of Pediatrics, National Key Clinical Specialty of Pediatric Respiratory Medicine, Discipline of Pediatric Respiratory Medicine, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou 325027, China) ,  Chu Xuran (Cardio-Pulmonary Institute, Universities of Giessen and Marburg Lung Center, Member of the German Center for Lung Research, Justus-Liebig-University Giessen, 35392 Giessen, Germany) ,  Chu Xuran (School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, China) ,  Shrestha Amit (Cardio-Pulmonary Institute, Universities of Giessen and Marburg Lung Center, Member of the German Center for Lung Research, Justus-Liebig-University Giessen, 35392 Giessen, Germany) ,  Behnke Judith (Department of General Pediatrics and Neonatology, Justus-Liebig-University, Feulgenstrasse 12, D-35392 Giessen, Universities of Giessen and Marburg Lung Center, German Center for Lung Research, 35392 Giessen, Germany) ,  Ehrhardt Harald (Department of General Pediatrics and Neonatology, Justus-Liebig-University, Feulgenstrasse 12, D-35392 Giessen, Universities of Giessen and Marburg Lung Center, German Center for Lung Research, 35392 Giessen, Germany) ,  Zhang Jinsan (Key Laboratory of Interventional Pulmonology of Zhejiang Province, Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325035, China) ,  Zhang Jinsan (School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, China) ,  Zhang Jinsan (International Collaborative Center on Growth Factor Research, Life Science Institute, Wenzhou University, Wenzhou 325035, China) ,  Chen Chengshui (Key Laboratory of Interventional Pulmonology of Zhejiang Province, Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325035, China) ,  Bellusci Saverio (Key Laboratory of Interventional Pulmonology of Zhejiang Province, Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325035, China) ,  Bellusci Saverio (Cardio-Pulmonary Institute, Universities of Giessen and Marburg Lung Center, Member of the German Center for Lung Research, Justus-Liebig-University Giessen, 35392 Giessen, Germany)
資料名： Cells (Web)  (Cells (Web))
巻： 9  号： 8  ページ： 1875  発行年： 2020年 
JST資料番号： U7155A  ISSN： 2073-4409  資料種別： 逐次刊行物 (A)
記事区分： 文献レビュー  発行国： スイス (CHE)  言語： 英語 (EN)

抄録/ポイント： 北道による気管支肺異形成(BPD)の最初の記述の50年以上後に,多くの早産児に影響するこの慢性肺疾患はまだ十分に理解されていない。さらに,重症BPDに罹患した早産児の約40%もBroncho肺異形成関連肺高血圧症(BPD-PH)に罹患し,総罹患率と死亡率の有意な増加をもたらす。今日まで,BPDとBPD-PHの両方に対する治療はない。成長因子が肺血管系の正常および病理発生において中心的役割を果たすことはますます明らかになってきた。したがって,本レビューの目的は,疾患発生,進行および分解能に寄与する線維芽細胞成長因子(FGF)/FGF10シグナル伝達経路の潜在的役割に焦点を当てて,基本的な科学的観点からBPD-PHの理解における最近の証拠を要約することである。Copyright 2021 The Author(s) All rights reserved. Translated from English into Japanese by JST.【JST・京大機械翻訳】

シソーラス用語： 分解能 ,  死亡率 ,  FGF【成長因子】 ,  成長因子 ,  *ターゲティング ,  *肺高血圧症 ,  病理
準シソーラス用語： *化生 ,  気管支肺形成異常 ,  早産児 ,  *肺血管 ,  慢性肺疾患 ,  伝達経路 , 【Automatic Indexing@JST】

著者キーワード (3件)： 気管支肺異形成症 ,  肺高血圧症 ,  FGFシグナリング

分類 (1件)： 呼吸器の基礎医学  (GI01020H)

引用文献 (134件)：

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タイトルに関連する用語 (10件)： 気管支肺異形成 ,  肺高血圧症 ,  BPD ,  pH ,  標的化 ,  肺血管 ,  発達 ,  FGF ,  シグナル伝達経路 ,  役割