文献

J-GLOBAL ID：202102252005647998   整理番号：21A0070805

後および前循環脳卒中を比較する急性虚血性脳卒中および心房細動患者における経口抗凝固薬の開始のタイミング【JST・京大機械翻訳】

Timing of initiation of oral anticoagulants in patients with acute ischemic stroke and atrial fibrillation comparing posterior and anterior circulation strokes

著者 (103件)： Paciaroni Maurizio (Stroke Unit and Division of Cardiovascular Medicine, University of Perugia, Perugia, Italy) ,  Agnelli Giancarlo (Stroke Unit and Division of Cardiovascular Medicine, University of Perugia, Perugia, Italy) ,  Giustozzi Michela (Stroke Unit and Division of Cardiovascular Medicine, University of Perugia, Perugia, Italy) ,  Tsivgoulis Georgios (Department of Neurology, University of Tennessee Health Science Center, Memphis, TN, USA) ,  Tsivgoulis Georgios (Second Department of Neurology, National & Kapodistrian University of Athens, Athens, Greece) ,  Yaghi Shadi (Division of Stroke and Cerebrovascular Diseases, Department of Neurology, The Warren Alpert Medical School of Brown University, Providence, RI, USA) ,  Grory Brian Mac (Division of Stroke and Cerebrovascular Diseases, Department of Neurology, The Warren Alpert Medical School of Brown University, Providence, RI, USA) ,  Furie Karen L (Division of Stroke and Cerebrovascular Diseases, Department of Neurology, The Warren Alpert Medical School of Brown University, Providence, RI, USA) ,  Tadi Prasanna (Division of Stroke and Cerebrovascular Diseases, Department of Neurology, The Warren Alpert Medical School of Brown University, Providence, RI, USA) ,  Zedde Marialuisa (Neurology Unit, Stroke Unit, Arcispedale Santa Maria Nuova, Azienda Unita Sanitaria Locale - IRCCS, Reggio Emilia, Italy) ,  Abdul-Rahim Azmil H (Medical School and Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK) ,  Dawson Jesse (Medical School and Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK) ,  Lees Kennedy R (Medical School and Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK) ,  Alberti Andrea (Stroke Unit and Division of Cardiovascular Medicine, University of Perugia, Perugia, Italy) ,  Venti Michele (Stroke Unit and Division of Cardiovascular Medicine, University of Perugia, Perugia, Italy) ,  Acciarresi Monica (Stroke Unit and Division of Cardiovascular Medicine, University of Perugia, Perugia, Italy) ,  D’Amore Cataldo (Stroke Unit and Division of Cardiovascular Medicine, University of Perugia, Perugia, Italy) ,  Mosconi Maria Giulia (Stroke Unit and Division of Cardiovascular Medicine, University of Perugia, Perugia, Italy) ,  Bogini Valentina (Stroke Unit and Division of Cardiovascular Medicine, University of Perugia, Perugia, Italy) ,  Cappellari Manuel (SSO Stroke Unit, UO Neurologia, DAI di Neuroscienze, AOUI Verona, Italy) ,  Rigatelli Alberto (SSO Pronto Soccorso, Ospedale Borgo Trento, DAI Emergenza e Accettazione, AOUI Verona, Italy) ,  Bonetti Bruno (SSO Stroke Unit, UO Neurologia, DAI di Neuroscienze, AOUI Verona, Italy) ,  Putaala Jukka (Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland) ,  Tomppo Liisa (Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland) ,  Tatlisumak Turgut (Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Sweden) ,  Tatlisumak Turgut (Department of Neurology, Sahlgrenska University Hospital, Gothenburg, Sweden) ,  Bandini Fabio (Department of Neurology, Ospedale San Paolo, Savona, Italy) ,  Marcheselli Simona (Neurologia d’urgenza e Stroke Unit, Istituto Clinico Humanitas, Milano, Italy) ,  Pezzini Alessandro (Department of Clinical and Experimental Sciences, Neurology Unit, University of Brescia, Brescia, Italy) ,  Poli Loris (Department of Clinical and Experimental Sciences, Neurology Unit, University of Brescia, Brescia, Italy) ,  Padovani Alessandro (Department of Clinical and Experimental Sciences, Neurology Unit, University of Brescia, Brescia, Italy) ,  Masotti Luca (Internal Medicine, San Giuseppe Hospital, Empoli, Italy) ,  Grifoni Elisa (Internal Medicine, San Giuseppe Hospital, Empoli, Italy) ,  Vannucchi Vieri (Internal Medicine, San Giuseppe Hospital, Empoli, Italy) ,  Sohn Sung-Il (Department of Neurology, Keimyung University School of Medicine, Daegu, South Korea) ,  Lorenzini Gianni (SC Medicina e Chirurgia d’Accettazione e d’Urgenza, Ospedale Lotti Pontedera, Azienda USL Toscana Nordovest, Italy) ,  Tassi Rossana (Stroke Unit, AOU Senese, Siena, Italy) ,  Guideri Francesca (Stroke Unit, AOU Senese, Siena, Italy) ,  Acampa Maurizio (Stroke Unit, AOU Senese, Siena, Italy) ,  Martini Giuseppe (Stroke Unit, AOU Senese, Siena, Italy) ,  Ntaios George (Department of Internal Medicine, Faculty of Medicine, University of Thessaly, Larissa, Greece) ,  Athanasakis George (Department of Internal Medicine, Faculty of Medicine, University of Thessaly, Larissa, Greece) ,  Makaritsis Konstantinos (Department of Internal Medicine, Faculty of Medicine, University of Thessaly, Larissa, Greece) ,  Karagkiozi Efstathia (Department of Internal Medicine, Faculty of Medicine, University of Thessaly, Larissa, Greece) ,  Vadikolias Konstantinos (Department of Neurology, Democritus University of Thrace, Xanthi, Greece) ,  Liantinioti Chrissoula (Second Department of Neurology, National & Kapodistrian University of Athens, Athens, Greece) ,  Palaiodimou Lina (Second Department of Neurology, National & Kapodistrian University of Athens, Athens, Greece) ,  Mumoli Nicola (Department of Internal Medicine, Ospedale “Fornaroli” di Magenta (Milano), Italy) ,  Porta Cesare (Department of Internal Medicine, Ospedale “Fornaroli” di Magenta (Milano), Italy) ,  Galati Franco (Stroke Unit, Jazzolino Hospital, Vibo Valentia, Italy) ,  Sacco Simona (Department of Applied Clinical Sciences and Biotechnology, University of L’Aquila, L’Aquila, Italy) ,  Tiseo Cindy (Department of Applied Clinical Sciences and Biotechnology, University of L’Aquila, L’Aquila, Italy) ,  Corea Francesco (Neurologia - Stroke Unit, San Giovanni Battista Hospital, Foligno, Italy) ,  Ageno Walter (Department of Medicine and Surgery, University of Insubria, Varese, Italy) ,  Bellesini Marta (Department of Medicine and Surgery, University of Insubria, Varese, Italy) ,  Silvestrelli Giorgio (S.C. di Neurologia e S.S. di Stroke Unit, ASST di Mantova, Mantova, Italy) ,  Ciccone Alfonso (S.C. di Neurologia e S.S. di Stroke Unit, ASST di Mantova, Mantova, Italy) ,  Scoditti Umberto (Neuroscience Department, University of Parma, Parma, Italy) ,  Denti Licia (Dipartimento Geriatrico Riabilitativo, University of Parma, Parma, Italy) ,  Mancuso Michelangelo (Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy) ,  Caselli Maria C (Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy) ,  Maccarrone Miriam (Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy) ,  Ulivi Leonardo (Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy) ,  Orlandi Giovanni (Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy) ,  Orlandi Giovanni (Neurologia, Ospedale Apuano, Massa Carrara, Italy) ,  Giannini Nicola (Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy) ,  Tassinari Tiziana (Department of Neurology, Santa Corona Hospital, Pietra Ligure (Savona), Italy) ,  Lodovici Maria L De (Stroke Unit, Neurology, Insubria University, Varese, Italy) ,  Rueckert Christina (Abteilung fuer Neurologie, Oberschwabenklinik gGmbH, Ravensburg, Germany) ,  Baldi Antonio (Stroke Unit, Ospedale di Portogruaro, Portogruaro (Venice), Italy) ,  Toni Danilo (Department of Human Neurosciences, Sapienza University of Rome, Rome, Italy) ,  Gentile Luana (Department of Human Neurosciences, Sapienza University of Rome, Rome, Italy) ,  Letteri Federica (Department of Human Neurosciences, Sapienza University of Rome, Rome, Italy) ,  Giuntini Martina (Neurologia, Ospedale Apuano, Massa Carrara, Italy) ,  Lotti Enrico M (U.O. Neurologia Presidio Ospedaliero di Ravenna Azienda USL della Romagna, Italy) ,  Flomin Yuriy (Stroke and Neurorehabilitation Unit MC ‘Universal Clinic ‘Oberig’ Kyiv, Ukraine) ,  Pieroni Alessio (Department of Human Neurosciences, Sapienza University of Rome, Rome, Italy) ,  Kargiotis Odysseas (Stroke Unit, Metropolitan Hospital, Piraeus, Greece) ,  Karapanayiotides Theodore (2nd Department of Neurology, AHEPA University Hospital, Thessaloniki, Greece) ,  Monaco Serena (Stroke Unit, Ospedale Civico, Palermo, Italy) ,  Mannino Marina (Stroke Unit, Ospedale Civico, Palermo, Italy) ,  Baronello Mario M (Stroke Unit, Ospedale Civico, Palermo, Italy) ,  Csiba Laszlo (Stroke Unit, University of Debrecen, Debrecen, Hungary) ,  Szabo Lilla (Stroke Unit, University of Debrecen, Debrecen, Hungary) ,  Chiti Alberto (Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy) ,  Chiti Alberto (Neurologia, Ospedale Apuano, Massa Carrara, Italy) ,  Chiti Alberto (Department of Neurology, Sant’Andrea Hospital, La Spezia, Italy) ,  Giorli Elisa (Department of Neurology, Sant’Andrea Hospital, La Spezia, Italy) ,  Sette Massimo Del (Department of Neurology, Sant’Andrea Hospital, La Spezia, Italy) ,  Sette Massimo Del (Divisione di Neurologia, Ospedale Galliera, Genoa, Italy) ,  Schirinzi Erika (Divisione di Neurologia, Ospedale Galliera, Genoa, Italy) ,  Imberti Davide (Department of Internal Medicine, Ospedale Civile di Piacenza, Piacenza, Italy) ,  Zabzuni Dorjan (Department of Internal Medicine, Ospedale Civile di Piacenza, Piacenza, Italy) ,  Doronin Boris (Municipal Budgetary Healthcare Institution of Novosibirsk, Novosibirsk State Medical University, Novosibirsk, Russia) ,  Volodina Vera (Municipal Budgetary Healthcare Institution of Novosibirsk, Novosibirsk State Medical University, Novosibirsk, Russia) ,  Michel Patrik (Centre Cerebrovasculaire, Service de Neurologie, Departement des Neurosciences Cliniques Centre Hopitalier Universitaire Vaudois, Lausanne, Switzerland) ,  Eskandari Ashraf (Centre Cerebrovasculaire, Service de Neurologie, Departement des Neurosciences Cliniques Centre Hopitalier Universitaire Vaudois, Lausanne, Switzerland) ,  Vanacker Peter (Department of Neurology, Antwerp University Hospital and Antwerp University, Antwerp, Belgium) ,  Barlinn Kristian (Department of Neurology, Dresden University Stroke Center, Dresden, Germany) ,  Barlinn Jessica (Department of Neurology, Dresden University Stroke Center, Dresden, Germany) ,  Deleu Dirk (Neurology, Hamad Medical Corporation, Doha, Qatar) ,  Gourbali Vanessa (Department of Neurology, Evangelismos Hospital, Athens, Greece) ,  Caso Valeria (Stroke Unit and Division of Cardiovascular Medicine, University of Perugia, Perugia, Italy)
資料名： European Stroke Journal  (European Stroke Journal)
巻： 5  号： 4  ページ： 374-383  発行年： 2020年 
JST資料番号： W5208A  ISSN： 2396-9873  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： アメリカ合衆国 (USA)  言語： 英語 (EN)

抄録/ポイント： 導入:急性後方虚血発作(PS)と心房細動(AF)患者における本研究の目的は,(1)再発性虚血イベントと重症出血のリスク,および(2)経口抗凝固療法(OAT)とタイミングとの関係におけるこれらのリスクを評価することであった。材料と方法:PS患者を前向きに含めた;これらの患者の転帰イベントを,以前の登録から取った前脳卒中(AS)の患者と比較した。主要転帰は,脳卒中再発,一過性虚血発作,症候性全身性塞栓症,症候性脳出血および急性脳卒中から90日以内に起こる主要な頭蓋外出血の複合体であった。結果:合計2470人の患者が分析に利用可能であった:PSで473(19.1%),ASで1997(80.9%)。90日にわたって,213(8.6%)一次転帰イベントが記録された:AS患者の175(8.7%)とPS患者の38(8.0%)。OATを2日以内に開始した患者において,原発性転帰は,AS(OR 1.07;95%CI 0.39~2.94)を有する373人の患者中21人(4.3%)と比較して,PSで95人の患者中5人(5.3%)で生じた。3日と7日の間にOATを開始した患者において,一次転帰は,AS(OR 0.54;95%CI 0.16-1.80)を有する490人の患者中26人(5.3%)と比較して,PSで103人の患者中3人(2.9%)で生じた。考察:著者らの知見は,経口抗凝固を開始する時間を決定するとき,前または後部のいずれかの脳卒中の位置は,転帰イベントのリスクを予測しないことを示唆する。結論:PSまたはASとAFの患者は,OATの開始のタイミングに関して,90日で虚血または出血イベントの同様のリスクを有するようである。Copyright European Stroke Organisation 2020 Translated from English into Japanese by JST.【JST・京大機械翻訳】

シソーラス用語： *凝固 ,  出血 ,  *心房細動 ,  *虚血 ,  複合体 ,  *脳卒中 ,  発作 ,  脳出血
準シソーラス用語： 一過性脳虚血発作 ,  *急性虚血性脳卒中 ,  急性脳卒中 ,  *経口抗凝固薬 ,  経口抗凝固療法 ,  全身性塞栓症 , 【Automatic Indexing@JST】

著者キーワード (3件)： 急性脳卒中 ,  心房細動 ,  脳卒中再発

分類 (2件)： 循環系疾患の薬物療法  (GJ05020M) ,  血液・体液作用薬の臨床への応用  (GW14020X)

タイトルに関連する用語 (6件)： 循環 ,  脳卒中 ,  急性虚血性脳卒中 ,  心房細動 ,  患者 ,  経口抗凝固薬