文献

J-GLOBAL ID：202102280569312967   整理番号：21A0196737

心不全におけるエキソソームmiRNAの役割【JST・京大機械翻訳】

Role of Exosomal miRNAs in Heart Failure

著者 (25件)： Xue Ruicong (Department of Cardiology, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China) ,  Xue Ruicong (NHC Key Laboratory of Assisted Circulation, Sun Yat-sen University, Guangzhou, China) ,  Xue Ruicong (National-Guangdong Joint Engineering Laboratory for Diagnosis and Treatment of Vascular Diseases, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China) ,  Tan Weiping (Department of Respiratory, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China) ,  Wu Yuzhong (Department of Cardiology, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China) ,  Wu Yuzhong (NHC Key Laboratory of Assisted Circulation, Sun Yat-sen University, Guangzhou, China) ,  Wu Yuzhong (National-Guangdong Joint Engineering Laboratory for Diagnosis and Treatment of Vascular Diseases, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China) ,  Dong Bin (Department of Cardiology, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China) ,  Dong Bin (NHC Key Laboratory of Assisted Circulation, Sun Yat-sen University, Guangzhou, China) ,  Dong Bin (National-Guangdong Joint Engineering Laboratory for Diagnosis and Treatment of Vascular Diseases, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China) ,  Xie Zengshuo (Department of Cardiology, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China) ,  Xie Zengshuo (NHC Key Laboratory of Assisted Circulation, Sun Yat-sen University, Guangzhou, China) ,  Xie Zengshuo (National-Guangdong Joint Engineering Laboratory for Diagnosis and Treatment of Vascular Diseases, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China) ,  Huang Peisen (Department of Cardiology, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China) ,  Huang Peisen (NHC Key Laboratory of Assisted Circulation, Sun Yat-sen University, Guangzhou, China) ,  Huang Peisen (National-Guangdong Joint Engineering Laboratory for Diagnosis and Treatment of Vascular Diseases, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China) ,  He Jiangui (Department of Cardiology, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China) ,  He Jiangui (NHC Key Laboratory of Assisted Circulation, Sun Yat-sen University, Guangzhou, China) ,  He Jiangui (National-Guangdong Joint Engineering Laboratory for Diagnosis and Treatment of Vascular Diseases, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China) ,  Dong Yugang (Department of Cardiology, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China) ,  Dong Yugang (NHC Key Laboratory of Assisted Circulation, Sun Yat-sen University, Guangzhou, China) ,  Dong Yugang (National-Guangdong Joint Engineering Laboratory for Diagnosis and Treatment of Vascular Diseases, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China) ,  Liu Chen (Department of Cardiology, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China) ,  Liu Chen (NHC Key Laboratory of Assisted Circulation, Sun Yat-sen University, Guangzhou, China) ,  Liu Chen (National-Guangdong Joint Engineering Laboratory for Diagnosis and Treatment of Vascular Diseases, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China)
資料名： Frontiers in Cardiovascular Medicine (Web)  (Frontiers in Cardiovascular Medicine (Web))
巻： 7  ページ： 592412  発行年： 2020年 
JST資料番号： U7061A  ISSN： 2297-055X  資料種別： 逐次刊行物 (A)
記事区分： 文献レビュー  発行国： スイス (CHE)  言語： 英語 (EN)

抄録/ポイント： 心不全は,特定の診断バイオマーカーおよび治療標的を欠く心血管疾患の大多数の最終転帰である。それは現在の治療にもかかわらず,大部分の心血管入院と死亡に寄与する。このため,心不全の診断と治療を改善する可能性のある分子を探索することが重要である。マイクロRNA(miRNA)は,心不全の過程の調節に関与することが報告されている小さな非コードRNAである。エキソソームにおけるmiRNAの発見後,miRNAの細胞内分布分析は研究者の注目を浴びている。増加する証拠は,エキソソームmiRNAが心不全に対する有望な診断および治療分子であることを示す。本レビューでは,分子および臨床研究の展望における心不全におけるエキソソームmiRNAの役割を要約した。Copyright 2021 The Author(s) All rights reserved. Translated from English into Japanese by JST.【JST・京大機械翻訳】

シソーラス用語： 心筋 ,  *心不全 ,  心血管疾患 ,  細胞内分布 ,  循環系 ,  線維症 ,  血管新生 ,  バイオマーカー
準シソーラス用語： *マイクロRNA ,  非翻訳RNA ,  *エキソソーム ,  治療標的 ,  臨床研究 , 【Automatic Indexing@JST】

著者キーワード (5件)： 心不全 ,  エキソソームmiRNA ,  心筋細胞肥大 ,  心臓線維化 ,  心筋血管新生

分類 (2件)： 循環系の基礎医学  (GJ01020K) ,  生物学的機能  (EB04020F)

引用文献 (69件)：

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タイトルに関連する用語 (4件)： 心不全 ,  エキソソーム ,  miRNA ,  役割