研課題
J-GLOBAL ID:202104012233828117  研究課題コード:13412061

金ナノ粒子および幹細胞を併用した滅菌および皮膚創傷治療応用へのin-vitro研究

実施期間:2013 - 2013
実施機関 (1件):
研究責任者: ( , 免疫学フロンティア研究センター )
研究概要:
The oil base formulation of gold nanorods with and withoutantibacterial peptides were prepared and characterized. Following this, the formulations were applied to resistant antibiotic bacteria (S. aureus MRSA) with laser irradiation at a near infrar ed wavelength (NIR). The results show that the complex of gold nanorod-antibacterial peptide in an oil base formulation (GNR/ abp/O) could decrease the cell viability of bacteria to around 53.4%. The results from my investigation of penetration of GNRs in a form of GNR/abp/O through the mouse skin, imply that GNR/abp/O formulation applied with laser irradiation could have a potential to destroy bacteria on the skin surface and may also be effective in the deeper areas of the skin.
研究制度:
研究所管機関:
国立研究開発法人科学技術振興機構

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