ウーチェン

ウーチェン | Wu Chen

所属機関・部署：
職名：研究員

研究分野 (4件)：応用分子細胞生物学 , 応用生物化学 , 神経科学一般 , 分子生物学

競争的資金等の研究課題 (1件)：

2017 - 2020 ライソゾーム病のバイオマーカ解析による病態解明、診断、治療に関する研究

論文 (11件)：

Takashi Miyajima, Ryo Saito, Hiroko Yanagisawa, Miki Igarashi, Chen Wu, Takeo Iwamoto, Yoshikatsu Eto. Characterization of cellular phenotypes in neurons derived from induced pluripotent stem cells of male patients with Fabry disease. Journal of inherited metabolic disease. 2022
Mohammad Arif Hossain, Minami Hasegawa-Ogawa, Yoko Manome, Miki Igarashi, Chen Wu, Ken Suzuki, Junko Igarashi, Takeo Iwamoto, Hirotaka James Okano, Yoshikatsu Eto. Generation and characterization of motor neuron progenitors and motor neurons using metachromatic leukodystrophy-induced pluripotent stem cells. Molecular genetics and metabolism reports. 2022. 31. 100852-100852
Ryo Saito, Takashi Miyajima, Takeo Iwamoto, Chen Wu, Ken Suzuki, Mohammad Arif Hossain, Miyo Munakata, Takumi Era, Yoshikatsu Eto. A neuropathological cell model derived from Niemann-Pick disease type C patient-specific iPSCs shows disruption of the p62/SQSTM1-KEAP1-NRF2 Axis and impaired formation of neuronal networks. Molecular genetics and metabolism reports. 2021. 28. 100784-100784
Chen Wu, Takeo Iwamoto, Mohammad Arif Hossain, Keiko Akiyama, Junko Igarashi, Takashi Miyajima, Yoshikatsu Eto. A combination of 7-ketocholesterol, lysosphingomyelin and bile acid-408 to diagnose Niemann-Pick disease type C using LC-MS/MS. PloS one. 2020. 15. 9. e0238624
Mohammad Arif Hossain, Chen Wu, Hiroko Yanagisawa, Takashi Miyajima, Keiko Akiyama, Yoshikatsu Eto. Future clinical and biochemical predictions of Fabry disease in females by methylation studies of the GLA gene. Molecular genetics and metabolism reports. 2019. 20. 100497-100497

MISC (2件)：

Rina Itagaki, Masahiro Endo, Hiroko Yanagisawa, Mohammad Arif Hossain, Keiko Akiyama, Takashi Miyajima, Chen Wu, Takeo Iwamoto, Junko Igarashi, Haruo Shintaku, et al. Neuronal ceroid lipofuscinosis (NCL) types 1 and 2: Enzyme characteristics of PPT1 and TPP1, and their high risk and newborn screenings. MOLECULAR GENETICS AND METABOLISM. 2019. 126. 2. S78-S78
Mohammad A. Hossain, Hiroko Yanagisawa, Takashi Miyajima, Chen Wu, Rina Itagaki, Keiko Akiyama, Takeo Iwamoto, Yoshikatsu Eto. The severity of phenotype for a heterozygous Fabry female patient correlates to the methylation of non-mutated allele. MOLECULAR GENETICS AND METABOLISM. 2017. 120. 1-2. S66-S67

学歴 (1件)：

2008 - 2012 東京工業大学環境化学

経歴 (1件)：

2015/10 - 現在一般財団法人脳神経疾患研究所先端医療研究センター

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