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J-GLOBAL ID：202202225053559075   整理番号：22A1026280

症例報告:自家造血幹細胞移植後のTeenagerにおける重症急性肺COVID-19【JST・京大機械翻訳】

Case Report: Severe Acute Pulmonary COVID-19 in a Teenager Post Autologous Hematopoietic Stem Cell Transplant

著者 (19件)： van der Velden Fabian J. S. (Paediatric Immunology, Infectious Diseases and Allergy, Great North Children’s Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom) ,  van der Velden Fabian J. S. (Faculty of Medical Sciences, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom) ,  van Delft Frederik (Paediatric Oncology, Great North Children’s Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom) ,  Owens Stephen (Paediatric Immunology, Infectious Diseases and Allergy, Great North Children’s Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom) ,  Llevadias Judit (Paediatric Intensive Care, Freeman Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom) ,  McKean Michael (Paediatric Respiratory Department, Great North Children’s Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom) ,  Pulford Lindsey (Paediatric Intensive Care, Freeman Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom) ,  Taha Yusri (Virology, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom) ,  Williamson Grace (Paediatric Intensive Care, Great North Children’s Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom) ,  Campbell-Hewson Quentin (Paediatric Oncology, Great North Children’s Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom) ,  Hambleton Sophie (Paediatric Immunology, Infectious Diseases and Allergy, Great North Children’s Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom) ,  Hambleton Sophie (Faculty of Medical Sciences, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom) ,  Payne Rebecca (Faculty of Medical Sciences, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom) ,  Duncan Christopher (Faculty of Medical Sciences, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom) ,  Duncan Christopher (Infectious Disease and Tropical Medicine, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom) ,  Johnston Catriona (Pharmacy, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom) ,  Spegarova Jarmila (Faculty of Medical Sciences, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom) ,  Emonts Marieke (Paediatric Immunology, Infectious Diseases and Allergy, Great North Children’s Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom) ,  Emonts Marieke (Faculty of Medical Sciences, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom)
資料名： Frontiers in Pediatrics (Web)  (Frontiers in Pediatrics (Web))
巻： 10  ページ： 809061  発行年： 2022年 
JST資料番号： U7090A  ISSN： 2296-2360  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： スイス (CHE)  言語： 英語 (EN)

抄録/ポイント： 小児における肺重症急性呼吸器症候群コロナウイルス2(SARS-CoV-2)感染は一般的に軽度であり,免疫不全小児におけるSARS-CoV-2感染は一般的に軽度である。小児患者の小割合は(心)呼吸障害により重症になり,集中治療を必要とする。著者らは,自己幹細胞移植の日にSARS-CoV-2(PCRによって検出)を得て,抗ウイルス薬,ステロイドと生物による免疫調節,およびECMOの併用で首尾よく治療された急性呼吸 distress迫症候群を発症したHodgkinリンパ腫を有する10代の症例を報告する。Copyright 2022 The Author(s) All rights reserved. Translated from English into Japanese by JST.【JST・京大機械翻訳】

シソーラス用語： 抗ウイルス薬 ,  子供 ,  Hodgkin病 ,  免疫不全症候群 ,  呼吸障害 ,  *症例報告
準シソーラス用語： SARSウイルス ,  膜型人工肺 ,  集中治療 ,  *幹細胞移植 ,  *自家造血幹細胞移植 ,  患児 ,  *COVID-19 , 【Automatic Indexing@JST】

著者キーワード (5件)： 小児 ,  COVID-19 ,  幹細胞移植 ,  免疫調節 ,  免疫不全

分類 (2件)： 感染症・寄生虫症一般  (GD01010H) ,  ウイルス感染の生理と病原性  (EG04042Y)

引用文献 (33件)：

• Viner RM, Ward JL, Hudson LD, Ashe M, Patel SV, Hargreaves D, et al. Systematic review of reviews of symptoms and signs of COVID-19 in children and adolescents. Arch Dis Child. (2020) 106:802-7. doi: 10.1101/2020.10.16.20213298
• Cevik M, Kuppalli K, Kindrachuk J, Peiris M. Virology, transmission, and pathogenesis of SARS-CoV-2. BMJ. (2020) 371:m3862. doi: 10.1136/bmj.m3862
• Whittaker E, Bamford A, Kenny J, Kaforou M, Jones CE, Shah P, et al. Clinical characteristics of 58 children with a pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2. JAMA. (2020) 324:259-69. doi: 10.1001/jama.2020.10369
• Feldstein LR, Tenforde MW, Friedman KG, Newhams M, Rose EB, Dapul H, et al. Characteristics and outcomes of US children and adolescents with Multisystem Inflammatory Syndrome In Children (MIS-C) compared with severe acute COVID-19. JAMA. (2021) 325:1074-87. doi: 10.1001/jama.2021.2091
• Royal College of Paediatrics and Child Health. COVID-19 - guidance for management of children admitted to hospital and for treatment of non-hospitalised children at risk of severe disease (2020). Available online at: https://www.rcpch.ac.uk/sites/default/files/2022-01/RCPCH%20COVID-19%20guidance%20for%20management%20of%20children%20admitted%20to%20hospital%20and%20non-hospitalised%20children%20at%20risk%20of%20severe%20disease%20-%205%20January%202022.pdf (accessed January 05, 2022). doi: 10.1001/jama.2021.2091

タイトルに関連する用語 (4件)： 症例報告 ,  自家造血幹細胞移植 ,  重症 ,  肺