文献

J-GLOBAL ID：202202239214997657   整理番号：22A0983065

軟サンゴ由来Aspergillus sp.SCSIO 41036由来の新規真菌代謝産物,アスパーベンゾフェノンAおよびベルシコラミドC【JST・京大機械翻訳】

Asperbenzophenone A and Versicolamide C, New Fungal Metabolites from the Soft Coral Derived Aspergillus sp. SCSIO 41036

著者 (17件)： Long Jieyi (CAS Key Laboratory of Tropical Marine Bio-Resources and Ecology/Guangdong Key Laboratory of Marine Materia Medica/Innovation Academy of South China Sea Ecology and Environmental Engineering, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, 510301, P. R. Chi...) ,  Long Jieyi (University of Chinese Academy of Sciences, 19 Yuquan Road, Beijing, 100049, P. R. China) ,  Pang Xiaoyan (CAS Key Laboratory of Tropical Marine Bio-Resources and Ecology/Guangdong Key Laboratory of Marine Materia Medica/Innovation Academy of South China Sea Ecology and Environmental Engineering, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, 510301, P. R. Chi...) ,  Pang Xiaoyan (Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou), Guangzhou, 511458, P. R. China) ,  Lin Xiuping (CAS Key Laboratory of Tropical Marine Bio-Resources and Ecology/Guangdong Key Laboratory of Marine Materia Medica/Innovation Academy of South China Sea Ecology and Environmental Engineering, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, 510301, P. R. Chi...) ,  Lin Xiuping (Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou), Guangzhou, 511458, P. R. China) ,  Liao Shengrong (CAS Key Laboratory of Tropical Marine Bio-Resources and Ecology/Guangdong Key Laboratory of Marine Materia Medica/Innovation Academy of South China Sea Ecology and Environmental Engineering, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, 510301, P. R. Chi...) ,  Liao Shengrong (Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou), Guangzhou, 511458, P. R. China) ,  Zhou Xuefeng (CAS Key Laboratory of Tropical Marine Bio-Resources and Ecology/Guangdong Key Laboratory of Marine Materia Medica/Innovation Academy of South China Sea Ecology and Environmental Engineering, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, 510301, P. R. Chi...) ,  Zhou Xuefeng (Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou), Guangzhou, 511458, P. R. China) ,  Wang Junfeng (CAS Key Laboratory of Tropical Marine Bio-Resources and Ecology/Guangdong Key Laboratory of Marine Materia Medica/Innovation Academy of South China Sea Ecology and Environmental Engineering, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, 510301, P. R. Chi...) ,  Wang Junfeng (Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou), Guangzhou, 511458, P. R. China) ,  Yang Bin (CAS Key Laboratory of Tropical Marine Bio-Resources and Ecology/Guangdong Key Laboratory of Marine Materia Medica/Innovation Academy of South China Sea Ecology and Environmental Engineering, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, 510301, P. R. Chi...) ,  Yang Bin (Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou), Guangzhou, 511458, P. R. China) ,  Liu Yonghong (CAS Key Laboratory of Tropical Marine Bio-Resources and Ecology/Guangdong Key Laboratory of Marine Materia Medica/Innovation Academy of South China Sea Ecology and Environmental Engineering, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, 510301, P. R. Chi...) ,  Liu Yonghong (University of Chinese Academy of Sciences, 19 Yuquan Road, Beijing, 100049, P. R. China) ,  Liu Yonghong (Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou), Guangzhou, 511458, P. R. China)
資料名： Chemistry & Biodiversity  (Chemistry & Biodiversity)
巻： 19  号： 3  ページ： e202100925  発行年： 2022年 
JST資料番号： W2529A  ISSN： 1612-1872  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： アメリカ合衆国 (USA)  言語： 英語 (EN)

抄録/ポイント： ソフトサンゴ由来真菌Aspergillus sp.SCSIO41036から,2種の新規化合物,アスペルベンゾフェノンA(1)およびベルコバミドC(5)を15種の既知化合物と共に単離した。それらの構造を,分光学的方法,ECD分析,および文献からのデータとの比較により解明した。バイオアッセイにおいて,化合物8は10μMの濃度でRAW264.7細胞においてリポ多糖類誘導一酸化窒素(NO)に対して有意な阻害活性を示した。さらに,抗アセチルコリンエステラーゼ活性アッセイにより,14は157.8μMのIC_50値で弱い阻害を示した。Copyright 2022 Wiley Publishing Japan K.K. All rights reserved. Translated from English into Japanese by JST.【JST・京大機械翻訳】

シソーラス用語： 濃度 ,  アセチルコリンエステラーゼ ,  *代謝産物 ,  バイオアッセイ ,  リポ多糖類 ,  *真菌類 ,  一酸化窒素 ,  *Aspergillus ,  *花虫類 ,  活性 ,  阻害 ,  RAW264.7細胞
準シソーラス用語： 分光学 ,  阻害活性 , 【Automatic Indexing@JST】

著者キーワード (4件)： Aspergillus ,  軟サンゴ ,  一酸化窒素 ,  アセチルコリンエステラーゼ阻害

分類 (2件)： 微生物の生化学  (EG03020N) ,  動植物,微生物のその他の産生物質  (CF10090R)

タイトルに関連する用語 (4件)： サンゴ ,  Aspergillus ,  真菌 ,  代謝産物