文献

J-GLOBAL ID：202202257298695341   整理番号：22A0729057

双極性障害における長期的構造的脳変化:ENIGMA双極性障害ワーキンググループによる1232人の個人の多施設神経画像研究【JST・京大機械翻訳】

Longitudinal Structural Brain Changes in Bipolar Disorder: A Multicenter Neuroimaging Study of 1232 Individuals by the ENIGMA Bipolar Disorder Working Group

著者 (120件)： Abe Christoph (Department of Clinical Neuroscience, Osher Center, Karolinska Institutet, Stockholm, Sweden) ,  Ching Christopher R.K. (Imaging Genetics Center, Mark and Mary Stevens Institute for Neuroimaging and Informatics, University of Southern California, Los Angeles, California) ,  Liberg Benny (Department of Clinical Neuroscience, Osher Center, Karolinska Institutet, Stockholm, Sweden) ,  Lebedev Alexander V. (Department of Clinical Neuroscience, Osher Center, Karolinska Institutet, Stockholm, Sweden) ,  Agartz Ingrid (Department of Clinical Neuroscience, Centre for Psychiatric Research, Karolinska Institutet, Stockholm, Sweden) ,  Agartz Ingrid (Norwegian Centre for Mental Disorders Research, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway) ,  Agartz Ingrid (KG Jebsen Centre for Neurodevelopmental Disorders, Institute of Clinical Medicine, University of Oslo, Oslo, Norway) ,  Agartz Ingrid (Department of Psychiatric Research, Diakonhjemmet Hospital, Oslo, Norway) ,  Akudjedu Theophilus N. (Institute of Medical Imaging and Visualisation, Bournemouth University, Bournemouth, United Kingdom) ,  Akudjedu Theophilus N. (Centre for Neuroimaging and Cognitive Genomics, Clinical Neuroimaging Laboratory, NCBES Galway Neuroscience Centre, College of Medicine, Nursing, and Health Sciences, National University of Ireland, Galway, Ireland) ,  Alda Martin (Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia) ,  Alda Martin (National Institute of Mental Health, Klecany, Czech Republic) ,  Alnaes Dag (Norwegian Centre for Mental Disorders Research, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway) ,  Alnaes Dag (Bjorknes College, Oslo, Norway) ,  Alonso-Lana Silvia (FIDMAG Germanes Hospitalaries Research Foundation, Barcelona, Spain) ,  Alonso-Lana Silvia (Centro de Investigacion Biomedica en Red de Salud Mental, Barcelona, Spain) ,  Benedetti Francesco (Psychiatry and Clinical Psychobiology Unit, Division of Neuroscience, IRCCS Ospedale San Raffaele, Milano, Italy) ,  Benedetti Francesco (University Vita-Salute San Raffaele, Milano, Italy) ,  Benedetti Francesco (Institute for Translational Psychiatry, University of Muenster, Muenster, Germany) ,  Berk Michael (Orygen, the National Centre of Excellence in Youth Mental Health, Centre for Youth Mental Health, Florey Institute for Neuroscience and Mental Health and the Department of Psychiatry, the University of Melbourne, Melbourne, Victoria, Australia) ,  Berk Michael (Department of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia) ,  Berk Michael (Deakin University, the Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Geelong, Victoria, Australia) ,  Boen Erlend (Unit of Psychosomatic and CL Psychiatry, Oslo University Hospital, Oslo, Norway) ,  Bonnin Caterina del Mar (Centro de Investigacion Biomedica en Red de Salud Mental, Barcelona, Spain) ,  Bonnin Caterina del Mar (Institut d’Investigacions Biomediques August Pi i Sunyer, Barcelona, Spain) ,  Bonnin Caterina del Mar (Barcelona Bipolar Disorders and Depressive Unit, Hospital Clinic, Institute of Neurosciences, Barcelona, Spain) ,  Bonnin Caterina del Mar (University of Barcelona, Barcelona, Spain) ,  Breuer Fabian (Psychiatry and Clinical Psychobiology Unit, Division of Neuroscience, IRCCS Ospedale San Raffaele, Milano, Italy) ,  Breuer Fabian (University Vita-Salute San Raffaele, Milano, Italy) ,  Breuer Fabian (Institute for Translational Psychiatry, University of Muenster, Muenster, Germany) ,  Brosch Katharina (Department of Psychiatry and Psychotherapy, Philipps-University Marburg, Marburg, Germany) ,  Brosch Katharina (Center for Mind, Brain and Behavior, University of Marburg and Justus Liebig, University of Giessen, Giessen, Germany) ,  Brouwer Rachel M. (Department of Psychiatry, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht, the Netherlands) ,  Brouwer Rachel M. (Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands) ,  Canales-Rodriguez Erick J. (FIDMAG Germanes Hospitalaries Research Foundation, Barcelona, Spain) ,  Canales-Rodriguez Erick J. (Centro de Investigacion Biomedica en Red de Salud Mental, Barcelona, Spain) ,  Canales-Rodriguez Erick J. (Signal Processing Laboratory, Ecole polytechnique federale de Lausanne, Lausanne, Switzerland) ,  Cannon Dara M. (Centre for Neuroimaging and Cognitive Genomics, Clinical Neuroimaging Laboratory, NCBES Galway Neuroscience Centre, College of Medicine, Nursing, and Health Sciences, National University of Ireland, Galway, Ireland) ,  Chye Yann (Turner Institute for Brain and Mental Health, School of Psychological Science and Monash Biomedical Imaging Facility, Monash University, Melbourne, Victoria, Australia) ,  Dahl Andreas (Norwegian Centre for Mental Disorders Research, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway) ,  Dahl Andreas (Department of Psychology, University of Oslo, Oslo, Norway) ,  Dandash Orwa (Department of Psychiatry, The University of Melbourne, Melbourne, Victoria, Australia) ,  Dannlowski Udo (Institute for Translational Psychiatry, University of Muenster, Muenster, Germany) ,  Dohm Katharina (Institute for Translational Psychiatry, University of Muenster, Muenster, Germany) ,  Elvsashagen Torbjorn (Norwegian Centre for Mental Disorders Research, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway) ,  Elvsashagen Torbjorn (Norwegian Centre for Mental Disorders Research, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway) ,  Elvsashagen Torbjorn (Department of Neurology, Division of Clinical Neuroscience, Oslo University Hospital, Oslo, Norway) ,  Fisch Lukas (Institute for Translational Psychiatry, University of Muenster, Muenster, Germany) ,  Fullerton Janice M. (School of Medical Sciences, University of New South Wales, Sydney, New South Wales, Australia) ,  Fullerton Janice M. (Neuroscience Research Australia, Sydney, New South Wales, Australia) ,  Goikolea Jose M. (Centro de Investigacion Biomedica en Red de Salud Mental, Barcelona, Spain) ,  Goikolea Jose M. (Institut d’Investigacions Biomediques August Pi i Sunyer, Barcelona, Spain) ,  Goikolea Jose M. (Barcelona Bipolar Disorders and Depressive Unit, Hospital Clinic, Institute of Neurosciences, Barcelona, Spain) ,  Goikolea Jose M. (University of Barcelona, Barcelona, Spain) ,  Grotegerd Dominik (Institute for Translational Psychiatry, University of Muenster, Muenster, Germany) ,  Haatveit Beathe (Norwegian Centre for Mental Disorders Research, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway) ,  Haatveit Beathe (Norwegian Centre for Mental Disorders Research, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway) ,  Hahn Tim (Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia) ,  Hahn Tim (National Institute of Mental Health, Klecany, Czech Republic) ,  Hahn Tim (Institute for Translational Psychiatry, University of Muenster, Muenster, Germany) ,  Hajek Tomas (Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia) ,  Hajek Tomas (National Institute of Mental Health, Klecany, Czech Republic) ,  Hajek Tomas (Institute for Translational Psychiatry, University of Muenster, Muenster, Germany) ,  Heindel Walter (Clinic for Radiology, University of Muenster, Muenster, Germany) ,  Ingvar Martin (Department of Clinical Neuroscience, Osher Center, Karolinska Institutet, Stockholm, Sweden) ,  Ingvar Martin (Karolinska University Hospital, Department of Neuroradiology, Stockholm, Sweden) ,  Sim Kang (Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore) ,  Sim Kang (Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore) ,  Sim Kang (West Region, Institute of Mental Health, Singapore, Singapore) ,  Sim Kang (Institute for Translational Psychiatry, University of Muenster, Muenster, Germany) ,  Kircher Tilo T.J. (Department of Psychiatry and Psychotherapy, Philipps-University Marburg, Marburg, Germany) ,  Kircher Tilo T.J. (Center for Mind, Brain and Behavior, University of Marburg and Justus Liebig, University of Giessen, Giessen, Germany) ,  Lenroot Rhoshel K. (University of New Mexico, Albuquerque, New Mexico) ,  Malt Ulrik F. (Department of Neurology, Oslo University Hospital, Oslo, Norway) ,  Malt Ulrik F. (Department of Psychiatry and Addiction, Section for C-L Psychiatry and Psychosomatics, Oslo University Hospital, Oslo, Norway) ,  McDonald Colm (Centre for Neuroimaging and Cognitive Genomics, Clinical Neuroimaging Laboratory, NCBES Galway Neuroscience Centre, College of Medicine, Nursing, and Health Sciences, National University of Ireland, Galway, Ireland) ,  McWhinney Sean R. (Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia) ,  Melle Ingrid (Norwegian Centre for Mental Disorders Research, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway) ,  Melle Ingrid (Norwegian Centre for Mental Disorders Research, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway) ,  Meller Tina (Department of Psychiatry and Psychotherapy, Philipps-University Marburg, Marburg, Germany) ,  Meller Tina (Center for Mind, Brain and Behavior, University of Marburg and Justus Liebig, University of Giessen, Giessen, Germany) ,  Melloni Elisa M.T. (Psychiatry and Clinical Psychobiology Unit, Division of Neuroscience, IRCCS Ospedale San Raffaele, Milano, Italy) ,  Melloni Elisa M.T. (University Vita-Salute San Raffaele, Milano, Italy) ,  Mitchell Philip B. (School of Psychiatry, University of New South Wales, Sydney, New South Wales, Australia) ,  Nabulsi Leila (Imaging Genetics Center, Mark and Mary Stevens Institute for Neuroimaging and Informatics, University of Southern California, Los Angeles, California) ,  Nabulsi Leila (Centre for Neuroimaging and Cognitive Genomics, Clinical Neuroimaging Laboratory, NCBES Galway Neuroscience Centre, College of Medicine, Nursing, and Health Sciences, National University of Ireland, Galway, Ireland) ,  Nenadic Igor (Department of Psychiatry and Psychotherapy, Philipps-University Marburg, Marburg, Germany) ,  Nenadic Igor (Center for Mind, Brain and Behavior, University of Marburg and Justus Liebig, University of Giessen, Giessen, Germany) ,  Opel Nils (Institute for Translational Psychiatry, University of Muenster, Muenster, Germany) ,  Overs Bronwyn J. (Neuroscience Research Australia, Sydney, New South Wales, Australia) ,  Panicalli Francesco (Hospital general de Granollers, Barcelona, Spain) ,  Panicalli Francesco (Benito Menni CASM, Barcelona, Spain) ,  Pfarr Julia-Katharina (Department of Psychiatry and Psychotherapy, Philipps-University Marburg, Marburg, Germany) ,  Pfarr Julia-Katharina (Center for Mind, Brain and Behavior, University of Marburg and Justus Liebig, University of Giessen, Giessen, Germany) ,  Poletti Sara (Psychiatry and Clinical Psychobiology Unit, Division of Neuroscience, IRCCS Ospedale San Raffaele, Milano, Italy) ,  Pomarol-Clotet Edith (FIDMAG Germanes Hospitalaries Research Foundation, Barcelona, Spain) ,  Pomarol-Clotet Edith (Centro de Investigacion Biomedica en Red de Salud Mental, Barcelona, Spain) ,  Radua Joaquim (Center for Psychiatric Research, Department of Clinical Neuroscience, Karolinska Institutet and Stockholm Health Care Services, Stockholm County Council, Stockholm, Sweden) ,  Radua Joaquim (Early Psychosis: Interventions and Clinical-detection lab, Department of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, United Kingdom) ,  Radua Joaquim (Centro de Investigacion Biomedica en Red de Salud Mental, Barcelona, Spain) ,  Radua Joaquim (Institut d’Investigacions Biomediques August Pi i Sunyer, Barcelona, Spain) ,  Radua Joaquim (Institute for Translational Psychiatry, University of Muenster, Muenster, Germany) ,  Repple Jonathan (Center for Psychiatric Research, Department of Clinical Neuroscience, Karolinska Institutet and Stockholm Health Care Services, Stockholm County Council, Stockholm, Sweden) ,  Repple Jonathan (Early Psychosis: Interventions and Clinical-detection lab, Department of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, United Kingdom) ,  Repple Jonathan (Centro de Investigacion Biomedica en Red de Salud Mental, Barcelona, Spain) ,  Repple Jonathan (Institut d’Investigacions Biomediques August Pi i Sunyer, Barcelona, Spain) ,  Repple Jonathan (Institute for Translational Psychiatry, University of Muenster, Muenster, Germany) ,  Ringwald Kai G. (Department of Psychiatry and Psychotherapy, Philipps-University Marburg, Marburg, Germany) ,  Ringwald Kai G. (Center for Mind, Brain and Behavior, University of Marburg and Justus Liebig, University of Giessen, Giessen, Germany) ,  Roberts Gloria (School of Psychiatry, University of New South Wales, Sydney, New South Wales, Australia) ,  Rodriguez-Cano Elena (FIDMAG Germanes Hospitalaries Research Foundation, Barcelona, Spain) ,  Rodriguez-Cano Elena (Benito Menni CASM, Barcelona, Spain) ,  Salvador Raymond (FIDMAG Germanes Hospitalaries Research Foundation, Barcelona, Spain) ,  Salvador Raymond (Centro de Investigacion Biomedica en Red de Salud Mental, Barcelona, Spain) ,  Sarink Kelvin (Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore) ,  Sarink Kelvin (Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore) ,  Sarink Kelvin (West Region, Institute of Mental Health, Singapore, Singapore) ,  Sarink Kelvin (Institute for Translational Psychiatry, University of Muenster, Muenster, Germany) ,  Sarro Salvador (FIDMAG Germanes Hospitalaries Research Foundation, Barcelona, Spain) ,  Sarro Salvador (Centro de Investigacion Biomedica en Red de Salud Mental, Barcelona, Spain)
資料名： Biological Psychiatry  (Biological Psychiatry)
巻： 91  号： 6  ページ： 582-592  発行年： 2022年 
JST資料番号： T0089A  ISSN： 0006-3223  CODEN： BIPCBF  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： オランダ (NLD)  言語： 英語 (EN)

抄録/ポイント： 双極性障害(BD)は皮質および皮質下構造脳異常と関連する。このような変化が時間とともに次第に変化するかどうか,およびこれが気分エピソードの数と関連するかどうかは不明である。この疑問に取り組むために,著者らは,BDにおける時間にわたる構造的脳変化を調べるために,縦磁気共鳴映像法(MRI)と臨床データを有する大規模で多様な国際的サンプルを分析した。BD患者307名および健康対照者925名を含む,ENIGMA(Meta分析による神経イメージング遺伝学)からの縦構造MRIおよび臨床データを,世界中の14部位から採取した。40±17歳の男性および女性参加者は,2時点でMRIを受けた。皮質厚さ,表面積および皮質下容積をFreeSurferを用いて推定した。各画像表現型の年間変化率をBD患者と健常対照被験者の間で比較した。患者内で,脳変化率を時間点間の気分エピソードの数に関連させ,人口統計学的および臨床的変数の効果を試験した。健康な対照被験者と比較して,BD患者は,心室容積のより速い拡大と紡錘状および傍海馬皮質のより遅い薄化を示した(0.18<d<0.22)。より多くの(低)人的エピソードは,主に前頭前野皮質において,より速い皮質間伐と関連していた。BDに関する今までの最大の縦MRI研究において,著者らは,BDにおいて,加速した皮質間伐を検出しなかったが,より速い心室拡大を認めた。しかし,異常な前頭皮質間伐は,頻繁な男性エピソードと関連して観察された。本研究はBDにおける疾患進行への洞察をもたらし,BD治療におけるマニア予防の重要性を強調する。Copyright 2022 Elsevier B.V., Amsterdam. All rights reserved. Translated from English into Japanese by JST.【JST・京大機械翻訳】

シソーラス用語： *脳 ,  心室 ,  精神医学 ,  *双極性障害 ,  大脳皮質 ,  海馬 ,  皮質 ,  統計学 ,  臨床医学 ,  前頭葉 ,  NMRイメージング ,  前頭前野
準シソーラス用語： 疾患進行 ,  人口統計学 ,  被験者 ,  臨床データ ,  前頭皮質 ,  *ニューロイメージング , 【Automatic Indexing@JST】

著者キーワード (6件)： 双極性障害 ,  ENIGMA ,  縦断的研究 ,  神経イメージング ,  神経進行 ,  精神医学

分類 (1件)： 精神障害  (GR03000A)

タイトルに関連する用語 (8件)： 双極性障害 ,  長期 ,  脳 ,  ワーキンググループ ,  個人 ,  施設 ,  神経画像 ,  研究