藤田有子

Fujita Yuko

所属機関・部署：
職名：特任助教

研究分野 (2件)：実験動物学 , 精神神経科学

研究キーワード (1件)：生物学的精神医学

競争的資金等の研究課題 (4件)：

2022 - 2025 抗精神病薬による薬剤耐性の予防法およびドパミン過感受性精神病解除法の探索
2021 - 2024 (R)-ケタミンの抗うつ作用の分子機序解明に関する研究
2015 - 2017 脳脊髄液のメタボローム解析を用いた双極性障害の病態解明に関する研究
2012 - 2017 グルタミン酸シグナルを介した精神疾患病態に関するマイクロエンドフェノタイプの解明

論文 (97件)：

Dan Xu, Akifumi Eguchi, Rumi Murayama, Guilin Liu, Mingming Zhao, Tingting Zhu, Yi Cai, Yong Yue, Xiayun Wan, Yuko Fujita, et al. Effects of 3,4-methylenedioxymethamphetamine on the gut microbiota and metabolites in the small intestine, cecum, and colon of male rats. Progress in neuro-psychopharmacology & biological psychiatry. 2024. 136. 111223-111223
Yukihiko Shirayama, Masaaki Iwata, Kanako Miyano, Yuki Hirose, Yasunori Oda, Yuko Fujita, Kenji Hashimoto. Infusions of beta-hydroxybutyrate, an endogenous NLRP3 inflammasome inhibitor, produce antidepressant-like effects on learned helplessness rats through BDNF-TrkB signaling and AMPA receptor activation, and strengthen learning ability. Brain research. 2023. 1821. 148567-148567
Xingming Wang, Akifumi Eguchi, Yuko Fujita, Xiayun Wan, Lijia Chang, Yong Yang, Jiajing Shan, Youge Qu, Li Ma, Yukihiko Shirayama, et al. Abnormal compositions of gut microbiota and metabolites are associated with susceptibility versus resilience in rats to inescapable electric stress. Journal of affective disorders. 2023. 331. 369-379
Xiayun Wan, Akifumi Eguchi, Akemi Sakamoto, Yuko Fujita, Yong Yang, Youge Qu, Masahiko Hatano, Chisato Mori, Kenji Hashimoto. Impact of broad-spectrum antibiotics on the gut-microbiota-spleen-brain axis. Brain, behavior, & immunity - health. 2023. 27. 100573-100573
Li Ma, Jiancheng Zhang, Yuko Fujita, Hiroyo Shinno-Hashimoto, Jiajing Shan, Xiayun Wan, Youge Qu, Lijia Chang, Xingming Wang, Kenji Hashimoto. Effects of spleen nerve denervation on depression-like phenotype, systemic inflammation, and abnormal composition of gut microbiota in mice after administration of lipopolysaccharide: A role of brain-spleen axis. Journal of affective disorders. 2022. 317. 156-165

MISC (7件)：

Yaoyu Pu, Jun Yang, Lijia Chang, Youge Qu, Siming Wang, Kai Zhang, Zhongwei Xiong, Jiancheng Zhang, Yunfei Tan, Xingming Wang, et al. Maternal glyphosate exposure causes autism-like behaviors in offspring through increased expression of soluble epoxide hydrolase (vol 117, pg 11753, 2020). PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021. 118. 5
Kenji Hashimoto, Taisuke Yoshida, Masatomo Ishikawa, Yuko Fujita, Tomihisa Niitsu, Michiko Nakazato, Hiroyuki Watanabe, Tsuyoshi Sasaki, Akihiro Shiina, Tasuku Hashimoto, et al. Increased serum levels of serine enantiomers in patients with depression (vol 28, pg 173, 2015). ACTA NEUROPSYCHIATRICA. 2016. 28. 3. 184-184
Akiko Matsuura, Yuko Fujita, Masaomi Iyo, Kenji Hashimoto. Effects of sulforaphane in the maternal immune activation model of schizophrenia. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2016. 19. 182-183
Kenji Hashimoto, Hongxian Chen, Yuko Fujita, Jichun Zhang, Tamaki Ishima, Yumi Shirai, Jin Wu. SULFORAPHANE AS A POTENTIAL THERAPEUTIC DRUG FOR SCHIZOPHRENIA. SCHIZOPHRENIA RESEARCH. 2012. 136. S190-S190
Mao Horio, Tamaki Ishima, Mami Kohno, Yuko Fujita, Ran Inoue, Hisashi Mori, Kenji Hashimoto. Levels of amino acids in the brain and peripheral organs of serine racemase knock-out mice. AMINO ACIDS. 2011. 41. S18-S18

経歴 (2件)：

2007/02 - 現在千葉大学, 社会精神保健教育研究センター
2001/09 - 2007/01 千葉大学大学院医学研究院精神医学

受賞 (2件)：

2022 - 日本神経精神薬理学会 NPPR Article and Review Awards Dietary intake of glucoraphanin during pregnancy and lactation prevents the behavioral abnormalities in the offspring after maternal immune activation
2022 - 日本神経精神薬理学会 NPPR Article and Review Awards Decreased bone mineral density in ovariectomized mice is ameliorated after subsequent repeated intermittent administration of (R)-ketamine, but not (S)-ketamine

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藤田 有子

藤田有子