Rchr
J-GLOBAL ID:200901000465018672   Update date: Sep. 04, 2024

Uekita Takamasa

ウエキタ タカマサ | Uekita Takamasa
Affiliation and department:
Job title: Associate Professor
Research field  (4): Tumor biology ,  Experimental pathology ,  Pathobiochemistry ,  Cell biology
Research keywords  (10): シグナル伝達 ,  浸潤・転移 ,  細胞生物学 ,  機能生物化学 ,  腫瘍学 ,  Metastasis ,  Invasion ,  Cancer ,  Cell Biology ,  Functional Biochemistry
Research theme for competitive and other funds  (11):
  • 2021 - 2024 Basic research on the development of new therapeutic methods for cancer metastasis targeting the CDCP1 extracellular domain
  • 2020 - 2023 複合刺激応答型金属錯体に立脚した選択的抗がん剤の開発
  • 2015 - 2018 Basic research on cancer therapy development targeting anchorage independence
  • 2012 - 2015 Analysis of the mechanism of cancer progression that overcome the cellular senescence by activated Ras
  • 1998 - 2007 MT1-MMPの細胞内ドメインの機能解析
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Papers (29):
  • Masato Taoka, Ritsuko Kuwana, Tatsumi Fukube, Akiko Kashima, Yuko Nobe, Takamasa Uekita, Tohru Ichimura, Hiromu Takamatsu. Ionic liquid-assisted sample preparation mediates sensitive proteomic analysis of Bacillus subtilis spores. Scientific reports. 2024. 14. 1. 17366-17366
  • Takamasa Uekita, Reiko Yagi, Tohru Ichimura, Ryuichi Sakai. C9orf10/Ossa regulates the bone metastasis of established lung adenocarcinoma cell subline H322L-BO4 in a mouse model. Genes to cells : devoted to molecular & cellular mechanisms. 2024. 29. 4. 290-300
  • Masato Taoka, Kota Kamei, Akiko Kashima, Yuko Nobe, Takahiro Takekiyo, Takamasa Uekita, Tohru Ichimura. An ionic liquid-assisted sample preparation method for sensitive integral-membrane proteome analysis. Analytical biochemistry. 2023. 683. 115349-115349
  • Takafumi Tozawa, Kohichi Matsunaga, Tetsuro Izumi, Naotake Shigehisa, Takamasa Uekita, Masato Taoka, Tohru Ichimura. Ubiquitination-coupled liquid phase separation regulates the accumulation of the TRIM family of ubiquitin ligases into cytoplasmic bodies. PloS one. 2022. 17. 8. e0272700
  • Masato Taoka, Koji Horita, Takahiro Takekiyo, Takamasa Uekita, Yukihiro Yoshimura, Tohru Ichimura. An Ionic Liquid-Based Sample Preparation Method for Next-Stage Aggregate Proteomic Analysis. Analytical chemistry. 2019. 91. 21. 13494-13500
more...
MISC (50):
  • 中島 克彦, 上北 尚正, 黒澤 仁, 堺 隆一. 転移関連膜タンパク質CDCP1の切断による分泌とその機能(Secretion of cleaved CDCP1, a metastasis-related transmembrane protein, and its biological function). 日本癌学会総会記事. 2014. 73回. P-2176
  • 富山 新太, 上北 尚正, 山口 英樹, 上野 英明, 滝田 順子, 佐々木 一樹, 中川原 章, 森 健太郎, 堺 隆一. 新規ALK結合蛋白質であるFlotillin-1は、ALKの細胞膜結合の調節を介してALKシグナルを制御する(Flotillin-1 regulates oncogenic signaling in neuroblastoma cells by regulating ALK membrane association). 日本癌学会総会記事. 2014. 73回. J-3103
  • 富山 新太, 上北 尚正, 山口 英樹, 佐々木 一樹, 滝田 順子, 中川原 章, 森 健太郎, 堺 隆一. 新規ALK結合蛋白質であるFlotillin-1は、endocytosisを介してALKシグナルを制御する(Flotillin-1 is a novel ALK binding protein which regulates ALK signaling through receptor endocytosis). 日本癌学会総会記事. 2013. 72回. 15-15
  • 富山 新太, 上北 尚正, 山口 英樹, 鎌田 礼子, 佐々木 一樹, 中川原 章, 堺 隆一. 新規ALK結合蛋白質であるFlotillin-1は、endocytosisを介してALKシグナルを制御する(Flotillin-1 is a novel ALK binding protein which regulates ALK signaling through receptor endocytosis). 日本癌学会総会記事. 2012. 71回. 528-528
  • Ryuichi Sakai, Takamasa Uekita. CDCP1 links RAS and Src signaling pathways as a common effector for the promotion of tumor metastasis. CANCER RESEARCH. 2012. 72
more...
Books (1):
  • 実験医学(10月号) 細胞表層プロテオリシスによる細胞移動の調節
    羊土社 2003
Lectures and oral presentations  (1):
  • Regulation of metastasis and invasion by a novel Src substrate CDCP1
    (68th Annual Meeting of the Japanese Cancer Association (招待講演) 2009)
Education (3):
  • 1998 - 2002 The University of Tokyo Graduate School of Medicine
  • 1996 - 1998 The University of Tokyo Graduate School of Agricultural and Life Sciences Animal Resource Sciences
  • 1991 - 1995 Saitama University Faculty of Science Biochemistry
Professional career (2):
  • M.S. in Agriculture and Life Science (The University of Tokyo)
  • Ph.D. in Medical Science (The University of Tokyo)
Work history (8):
  • 2013/10 - 現在 National Defense Academy Department of Applied Chemistry, Genome Biology Associate Professor
  • 2012/11 - 2013/09 National Cancer Center Research Institute Division of Metastasis and Invasion Signaling senior Researcher
  • 2012/04 - 2012/10 National Cancer Center Reseach Institute Growth Factor Division senior Researcher
  • 2010/05 - 2012/03 National Cancer Center Reseach Institute Growth Factor Division Staff Scientist
  • 2003/05 - 2008/04 National Cancer Center Research Institute Growth Factor Division
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Awards (4):
  • 2017/07 - 日本がん転移学会 第26回日本がん転移学会 優秀ポスター賞
  • 2010/07 - 日本がん転移学会 第19回日本がん転移学会 優秀演題賞(口演)
  • 2002/07 - 日本がん転移学会 第11回日本がん転移学会 優秀演題賞(口演)
  • 2001/09 - Institute of Medical Science, University of Tokyo Founding symposium Excellent Research Award
Association Membership(s) (9):
米国癌学会 ,  日本生化学会 ,  日本分子生物学会 ,  日本がん転移学会 ,  日本癌学会 ,  The Japanese Biochemical Society ,  The Molecular Biology Society of Japan ,  The Japanese Association for Metastasis Research ,  The Japanese Cancer Association
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