Research theme for competitive and other funds (5):
2020 - 2023 Development of reactions based on trichloroacetimidate and synthetic studies of bioactive compounds
2014 - 2017 Synthetic studies of DNA adducts and its amidites for DNA adductome analysis.
2009 - 2011 Synthesis of a novel imaging agent aimed for preclinical diagnosis
2005 - 2007 抗生物質に見られるデオキシアミノ糖類の効率的合成法の確立と医薬創製への応用
1999 - 2000 新規抗腫瘍抗生物質ビセニスタチンの全合成およびその作用機構の解明
Papers (46):
Yoshitaka Matsushima, Yutaro Ito, Hiroyuki Konno. Total synthesis of the methyl glycoside of bradyrhizose via intramolecular pinacol coupling. Tetrahedron Letters. 2022. 106. 154060
Takahiro Fujimaki, Chikako Sato, Rei Yamamoto, Sayo Watanabe, Hikaru Fujita, Hidehiko Kikuno, Masayuki Sue, Yoshitaka Matsushima. Isolation of phenolic acids and tannin acids from Mangifera indica L. kernels as inhibitors of lipid accumulation in 3T3-L1 cells. Bioscience, Biotechnology and Biochemistry. 2022. 86. 5. 665-671
Yoshitaka Matsushima, Kohei Ishii, Alisa Huffaker, Eric A. Schmelz. Efficient synthesis of zealexin B1, a maize sesquiterpenoid phytoalexin, via Suzuki-Miyaura coupling. Tetrahedron Letters. 2022. 91. 153641
Yoshitaka Matsushima, Koki Nakamura. Concise and scalable synthesis of (±)-phosphonothrixin. Results in Chemistry. 2021. 3. 100251
Yuji Iwashita, Ippei Ohnishi, Yuto Matsushita, Shunsuke Ohtsuka, Takashi Yamashita, Keisuke Inaba, Atsuko Fukazawa, Hideto Ochiai, Keigo Matsumoto, Nobuhito Kurono, et al. Geospatial Assessments of DNA Adducts in the Human Stomach: A Model of Field Cancerization. Cancers. 2021. 13. 15. 3728
Y. Iwashita, Ohnishi, I, N. Kurabe, T. Yamashita, S. Ohtsuka, M. Suzuki, T. Kahyo, M. Iwaizumi, Y. Matsushima, Y. Totsuka, et al. Identification of gastric cancer-related DNA adducts by DNA adductome analysis. ENVIRONMENTAL AND MOLECULAR MUTAGENESIS. 2017. 58. S70-S70