Rchr
J-GLOBAL ID：200901001238477187
Update date: Oct. 31, 2024
Numata Tomohiro
ヌマタ トモヒロ | Numata Tomohiro
Affiliation and department：
Research field (3)：
Zoological sciences
, Applied biochemistry
, Physiology
Research theme for competitive and other funds (17)：
- 2022 - 2025 臓器特異的TRPM6/7機能抑制マウスを用いた新規病態モデル開発とその治療応用
- 2020 - 2025 Optical control of the plasma membrane functions by using dynamic exciton
- 2021 - 2024 分子間協働から創出される細胞容積調節能を利用した虚血性壊死からの救済策の開発
- 2018 - 2021 Elucidation of hepatocyte volume regulation and liver regeneration mechanism through TRPM2 activity.
- 2015 - 2019 Multi-hierarchical analysis of the role of TRPM4 subfamily members in cardiac atrial arrhythmogenicity
- 2015 - 2018 Localization and role of TRPM2 channel in the heart
- 2015 - 2018 Elucidation of activation mechanism for osmo-sensitive TRP channel and its physiological role
- 2013 - 2015 心臓における不整脈基質TRPM2チャネルの役割
- 2012 - 2015 The new activation mechanisms in TRPM2 channel and role of cell death
- 2011 - 2013 心臓における生体ストレス分子TRPチャネルの役割
- 2009 - 2013 Molecular characterization of volume-activated anion channels and elucidation of cell death-survival switching mechanisms
- 2010 - 2011 The functional analysis of epilepsy related gene TRPP3
- 2006 - 2010 Volume-sensor anion channel and mechano-sensor cation channel: Their functional modal shifts and molecular interaction
- 2008 - 2009 The role of TRP channel in cell death
- 2005 - 2008 Channel-mediated mechanisms of induction of and protection against cell death
- 2006 - 2007 Protection mechanism of CFTR against ischemia-reperfusion injury in heart
- 2005 - 2007 浸透圧センサーTRPチャネルの同定と細胞容積調節メカニズムにおける役割の解明
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Papers (114)：
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Hideaki Tagashira, Md Shenuarin Bhuiyan, Yasuharu Shinoda, Ichiro Kawahata, Tomohiro Numata, Kohji Fukunaga. Sigma-1 receptor is involved in modification of ER-mitochondria proximity and Ca2+ homeostasis in cardiomyocytes. Journal of pharmacological sciences. 2023. 151. 2. 128-133
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Tomohiro Numata, Kaori Sato-Numata, Masami Yoshino. Intermediate conductance Ca2+-activated potassium channels are activated by functional coupling with stretch-activated nonselective cation channels in cricket myocytes. Frontiers in Insect Science. 2023. 2
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Hideaki Tagashira, Fumiha Abe, Kaori Sato-Numata, Karen Aizawa, Kei Hirasawa, Yoshinobu Kure, Daiki Iwata, Tomohiro Numata. Cardioprotective effects of Moku-boi-to and its impact on AngII-induced cardiomyocyte hypertrophy. Frontiers in cell and developmental biology. 2023. 11. 1264076-1264076
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Yasunobu Okada, Tomohiro Numata, Ravshan Z Sabirov, Makiko Kashio, Peter G Merzlyak, Kaori Sato-Numata. Cell death induction and protection by activation of ubiquitously expressed anion/cation channels. Part 3: the roles and properties of TRPM2 and TRPM7. Frontiers in cell and developmental biology. 2023. 11. 1246955-1246955
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Tomohiro Numata, Kaori Sato-Numata, Meredith C Hermosura, Yasuo Mori, Yasunobu Okada. TRPM7 is an essential regulator for volume-sensitive outwardly rectifying anion channel. Communications biology. 2021. 4. 1. 599-599
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MISC (44)：
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沼田 朋大. イオンチャネルの細胞容積調節能における意義と医療応用を目指した新たな活性制御法の開発. 秋田医学. 2022. 49. 1. 1-9
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沼田 朋大, 佐藤 かお理[沼田]. 細胞生理機能制御のための光誘導性分子による脱分極機構の解明. 日本生理学雑誌. 2022. 84. 2. 36-36
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Tagashira Hideaki, Shinoda Yasuharu, Numata Tomohiro, Fukunaga Kohji. The regulation mechanisms of mitochondrial Ca2+ signaling mediated by cardiac Sigma-1 receptor. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2022. 96. 1-B-P-020
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沼田 朋大, 岡田 泰伸. 二つのタンパク質の協力で細胞の大きさを一定に保つメカニズムを解明. 日本生理学雑誌. 2021. 83. 3. 49-50
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沼田 朋大, 岡田 泰伸. 二つのタンパク質の協力で細胞の大きさを一定に保つメカニズムを解明. 日本生理学雑誌. 2021. 83. 3. 49-50
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Professional career (1)：
Work history (1)：
- 2021/10 - 現在 Akita University Graduate School of Medicine Doctoral Course in Medicine
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