2014 - 2016 Establishment of induced neurons (iN cells) derived from lysosomal disease patients involving neurological symptoms and elucidation of regulatory mechanism of neurodegeneration
2013 - 2016 中枢神経症状を伴うリソソーム病における神経変性メカニズムの解明
2011 - 2014 Development and application of efficient identification method for drugable proteins based on natural products and bioorganic chemistries
2010 - 2013 Analysis of brain infiltrating monocyteic cell in lysosomal disease
2013 - 先天性代謝異常症における発症機構の解明
2010 - 2011 ヘテロ環化合物ライブラリーからの幹細胞研究用分化誘導剤の探索
2007 - 2010 Analysis of activated glial cells by glycome abnoumality in lysosomal didease
2010 - 神経炎症に伴う細胞の脳内浸潤機構の解明と疾患治療への応用
2009 - 多発性骨髄腫由来ガン幹細胞に対する新規バイオマーカーの探索
2008 - 分子標的探索機能を備えたペプチドライブラリーからの抗がん作用ペプチドの同定
2007 - 胃粘膜表在性蛋白質に対する抗体を用いた胃がん内視鏡手術支援技術の開発
Show all
Papers (82):
Yuki Yoshino, Masaki Imanishi, Licht Miyamoto, Daisuke Tsuji, Reiko Akagi, Koichiro Tsuchiya, Yoshiki Kashiwada, Naonobu Tanaka. Dauferulins A-L, daucane-type sesquiterpenes from the roots of Ferula communis: Their structures and biological activities. Fitoterapia. 2024. 174. 105877-105877
Kondo, Y., Nakamura, T., Tsuji, D., Sato, R., Karanjit, S., Akagi, R., Namba, K. Development of 1,3a,6a-triazapentalene derivatives as practical erasable fluorescent cell staining reagents. Tetrahedron Letters. 2024. 138
Tanaka, N., Takizawa, R., Shimomoto, Y., Tsuji, D., Yonekura, K., Itoh, K., Akagi, R., Kashiwada, Y. Meroterpenes and prenylated benzoylphloroglucinol from the flowers of Hypericum formosanum. Phytochemistry. 2024. 220. 114016-114016
Ryosuke Watanabe, Daisuke Tsuji, Hiroki Tanaka, Michael Shintaro Uno, Yukiya Ohnishi, Shindai Kitaguchi, Tsuyoshi Matsugu, Ryuto Nakae, Hiromi Teramoto, Kei Yamamoto, et al. Lysoglycosphingolipids have the ability to induce cell death through direct PI3K inhibition. Journal of neurochemistry. 2023
Naonobu Tanaka, Ikko Shibata, Yusuke Tasaki, Yuki Yoshino, Daisuke Tsuji, Feng-Lai Lu, Xiao-Jie Yan, Xue-Rong Yang, Kohji Itoh, Reiko Akagi, et al. Acylated iridoid glucoside and xanthones from Canscora lucidissima: Their structures and ferroptosis inhibitory activity. Fitoterapia. 2023. 168. 105539-105539
瀧澤伶奈, 下元悠聖, 今林潔, 辻大輔, 辻大輔, 伊藤孝司, 柏田良樹, 田中直伸. Studies on the constituents of Hypericaceous plants (55): Structures and biological activity of prenylated acylphloroglucinols from the flowers of Hypericum sp. 日本薬学会年会要旨集(Web). 2023. 143rd