Kikkawa Yamato

2018 - 2021 Development of ultrasound-responsive nanobubbles containing genome editing tools and establishment of disease treatment system

2018 - 2021 Renewal of severely damaged livers by activating hepatic progenitor cells

2017 - 2020 Roles of CD239 on adhesion and migration of tumor cells

2017 - 2019 In vitro reconstruction of hepatic tissue

2016 - 2019 Development of antibody delivery system by ultrasound responsive nano bubble and breast cancer treatment strategy

2014 - 2016 The roles of laminin alpha5 in tumor invasion

2013 - 2015 Development of cell-specific essential peptide matrix (EP-Matrix)

2012 - 2015 Establishment of cell transplantation therapy for hepatic failure by hepatic stem/progenitor cells and/or hepatic organoids

2014 - 2015 上皮管腔組織における基底膜形成メカニズムの解明

2010 - 2014 Molecutar anatomy and medicinal application of laminins, a basement membrane protein

2011 - 2011 Roles of Lutheran in tumor cell adhesion and migration

2009 - 2011 Basic research for the production of human hepatocytes and the transplantation of hepatic tissues

2008 - 2010 Primary culture of hepatocytes on synthetic peptides mimicking the functions of laminin-111

2006 - 2007 ラミニンα5鎖の受容体結合部位とその結合メカニズムの解明

2005 - 2007 Research for the formation of hepatic organoids by using human hepatic progenitor cells and the model of artificial liver device incorporated with human hepatic organoids

2005 - 2007 Role of laminin alpha5 and its receptors in fibrotic liver and hepatocellular carcinoma

2005 - 2006 3次元細胞培養ゲル「ペプチドマトリックス」の創製

2004 - 2004 癌の浸潤・転移に関わるLutheran/B-CAMの研究

2002 - 2004 Identification of specific surface proteins in small hepatocytes and reconstruction of hepatic organoids ex vivo.

1999 - 2000 基底膜の主要成分であるラミニン・アイソフォームの構造と機能解析

1996 - 1997 A new physiologic function of tissue kallikrein family enzymes and processing of growth factor precursors

1996 - 1996 新しい細胞外マトリックス,ラドシン/ラミニン-5の機能解析