Furue Miho

フルエミホ | Furue Miho

Affiliation and department：
Job title： CEO

Research field (3)： Oral medicine , Developmental biology , Cell biology

Research keywords (1)：機能系基礎歯科学

Research theme for competitive and other funds (25)：

2016 - 2019 Development of toxicity evaluation method for new dental materials using human pluripotent stem cell-derived neural crest cells
2015 - 2018 Mechanisms underlying differentiation of human pluripotent stem cells into peripheral neurons
2013 - 2017 iPS細胞の品質変動と実用化を目指した培養技術の標準化に関する研究
2015 - 2016 ヒトES/iPS細胞からの内胚葉分化のための汎用的かつ高効率な新規足場材料の作製
2010 - 2016 ヒト幹細胞産業応用促進基盤技術開発/ヒト幹細胞実用化に向けた評価基盤技術の開発

2013 - 2015 Gene correction in iPS cells of premature aging syndrome toward clinical application by genome editing

2012 - 2015 Analysis of stem cell niche during early neural development

2012 - 2015 Mechanisms underlying craniofacial development from embryonic stem cells

2011 - 2014 ヒトES/iPS 細胞の実用化における幹細胞バンクの基盤整備についての研究

2009 - 2012 Induction of maxilla-facial bone with tooth from human induced pluripotent stem cells

2010 - 2012 Screening for signaling pathways regulating human ES/iPS cell self-renewal

2009 - 2011 ヒトES/iPS細胞の臨床応用可能な無血清培地開発

2009 - 2011 Epigenetics on transdifferentiation of ES cells toward TS cells

2008 - 2010 ヒトiPS細胞を用いた新規毒性評価系構築

2006 - 2008 Induction of mandibular bone and tooth germ from mouse embryonic stem cells by activin A

2002 - 2005 Cell-matrix interactions in bone formation and regeneration

2003 - 2004 Induction of tooth and jaws from embryonic stem cells by Activin A

2001 - 2002 Induction of maxillofacial oragns from undifferentiated primitive ectodermal cells by activin A

1996 - 1996 顎下腺の老化に及ぼすエストロゲンの影響

ヒトES/iPS細胞評価法開発

Induction of oral organs using Activin A and primitive ectodermal stem cells.

Regeneration of Salivary gland from stem cells by HGF and Activin A.

Mechanisms of periodontal disease in the patients with Down syndrome

Tooth development in vertebrates

Role of activin in salivary gland morphogenesis

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Papers (67)：

Kana Yanagihara, Yohei Hayashi, Yujung Liu, Tomoko Yamaguchi, Yasuko Hemmi, Minako Kokunugi, Kozue Uchio Yamada, Ken Fukumoto, Mika Suga, Satoshi Terada, et al. Trisomy 12 compromises the mesendodermal differentiation propensity of human pluripotent stem cells. In vitro cellular & developmental biology. Animal. 2024
Yuichi Mine, Mika Suga, Sumiyo Mimura, Memori Minoda, Takeshi Murayama, Hiroki Nikawa, Miho K. Furue. Cytotoxicity assay using a human pluripotent stem cell-derived cranial neural crest cell model. In Vitro Cellular & Developmental Biology - Animal. 2020
Suga M, Furue MK. Neural Crest Cell Models of Development and Toxicity: Cytotoxicity Assay Using Human Pluripotent Stem Cell-Derived Cranial Neural Crest Cell Model. Methods in molecular biology (Clifton, N.J.). 2019. 1965. 35-48
Hayashi Y, Ohnuma K, Furue MK. Pluripotent Stem Cell Heterogeneity. Advances in experimental medicine and biology. 2019. 1123. 71-94
Ayako Kumagai, Tsutomu Sasaki, Kenta Matsuoka, Masayoshi Abe, Toshihide Tabata, Yumi Itoh, Hiroyuki Fuchino, Sartagul Wugangerile, Mika Suga, Tomoko Yamaguchi, et al. Monitoring of glutamate-induced excitotoxicity by mitochondrial oxygen consumption. SYNAPSE. 2019. 73. 1. e22067

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MISC (77)：

Miho K. Furue, Mika Suga, Hiroaki Kii, Hiroko Eimori, Tomoro Dan, Yasujiro Kiyota. Live Cell Imaging System for Cell Culture Evaluation by Cell Culture Observation System. IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL. 2017. 53. 7. 661-662
Mika Suga, Hiroaki Kii, Takayuki Uozumi, Yasujiro Kiyota, Miho K. Furue. Development of a New Cell-based Assay Using Human ES/iPS Cell-derived Neural Stem Cells for Developmental Neurotoxicity (DNT) Testing. IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL. 2016. 52. 7. 794-794
Yohei Hayashi, Miho Kusuda Furue. Biological Effects of Culture Substrates on Human Pluripotent Stem Cells. Stem Cells International. 2016. 2016
加藤竜司, 吉田啓, 岡田光加, 長坂理紗子, 佐々木寛人, 蟹江慧, 菅三佳, 柳原佳奈, 福田隆之, 清田泰次郎, et al. 細胞形態情報を用いたiPS細胞培養手技の定量化. 再生医療. 2015. 14
加藤竜司, 岡田光加, 長坂理紗子, 佐々木寛人, 蟹江慧, 菅三佳, 柳原佳奈, 福田隆之, 清田泰次郎, 古江美保. コロニー形態情報を用いたiPS細胞株の特性解析. 再生医療. 2015. 14

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Books (1)：

Handbook of stem cells
Academic Press, San Diego 2004

Works (2)：

Induction of oral organs using Activin A and primitive ectodermal stem cells.
2000 -
Regeneration of Salivary gland from stem cells by HGF and Activin A
1997 -

Education (2)：

1986 - 1990 Graduate School of Dentistry, Hiroshima University
1980 - 1986 Hiroshima University Faculty of Dentistry

Professional career (2)：

D.D.S. (Hiroshima University)
-

Work history (9)：

2022/01 - 現在株式会社セルミミック代表取締役
2015 - 現在広島大学大学院医歯薬学総合研究科客員教授
2017 - 2022 株式会社ニコンヘルスケア事業部シニアフェロー
2011 - 2016 大阪大学大学院歯学研究科招へい教授
2009 - 2016 国立研究開発法人医薬基盤・健康・栄養研究所ヒト幹細胞応用開発室研究リーダー

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Committee career (5)：

2023 - 現在内閣府健康・医療戦略推本部再生・細胞医療・遺伝子治療開発協議会
2021 - 現在内閣府健康・医療戦略推進事務局日本医療研究開発機構審議会
- 2020 文部科学省科学技術・学術審議会専門委員会幹細胞・再生医学戦略作業部会
1999 - 2000 the Society for In Vitro Biology Program committee
1997 - 1999 日本組織培養学会幹事

Association Membership(s) (1)：

日本組織培養学会

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