Research keywords (8):
ゲノム
, Veterinary Medicine
, Genomics
, Molecular Biology
, Drug Metabolism
, 分子生物学
, 獣医学
, 薬物代謝学
Research theme for competitive and other funds (4):
2020 - 2023 Systematic identification and characterization of essential drug-metabolizing enzyme toward establishment of platform for drug metabolism research in veterinary species
2005 - 2007 Molecular mechanism of chemical-induced toxicity in fetal livers
Yasuhiro Uno, Miaki Makiguchi, Genki Ushirozako, Kyoko Tsukiyama-Kohara, Makiko Shimizu, Hiroshi Yamazaki. Molecular and functional characterization of flavin-containing monooxygenases (FMO1-6) in tree shrews. Comparative Biochemistry and Physiology Part - C: Toxicology and Pharmacology. 2024. 277
Yasuhiro Uno, Norie Murayama, Hiroshi Yamazaki. Novel Cytochrome P450 2C119 Enzymes in Cynomolgus and Rhesus Macaques Metabolize Progesterone, Diclofenac, and Omeprazole. Drug metabolism and disposition: the biological fate of chemicals. 2024. 52. 3. 266-273
Yasuhiro Uno, Osamu Yamato, Hiroshi Yamazaki. Transcript abundance of hepatic drug-metabolizing enzymes in two dog breeds compared with 14 species including humans. Drug Metabolism and Pharmacokinetics. 2024. 101002-101002
Tomoki Ootawa, Siyuan Wu, Ryoya Sekio, Henry Smith, Md. Zahorul Islam, Ha Thi Thanh Nguyen, Yasuhiro Uno, Mitsuya Shiraishi, Atsushi Miyamoto. Characterization of Vasoreactivity in a Semi-Arboreal Snake, the Tokara Habu (Protobothrops tokarensis). Animals. 2023. 13. 23. 3629-3629
Yasuhiro Uno, Shotaro Uehara, Genki Ushirozako, Tatsunori Masatani, Hiroshi Yamazaki. Chronic Toxoplasma infection affects gene expression of drug-metabolizing enzymes in mouse liver. Xenobiotica; the fate of foreign compounds in biological systems. 2023. 1-6