Rchr
J-GLOBAL ID:200901002841389310
Update date: Oct. 24, 2024
Ito Mikako
イトウ ミカコ | Ito Mikako
Affiliation and department:
Job title:
Lecturer
Other affiliations (1):
Research field (4):
Applied molecular and cellular biology
, Molecular biology
, Genetics
, Neuroscience - general
Research keywords (1):
神経筋接合部 先天性筋無力症候群 分子状水素 微弱磁場
Research theme for competitive and other funds (21):
- 2023 - 2026 Investigation of the molecular formations and the pathomechanisms of the neuromuscular junction
- 2023 - 2026 Study of mitochondrial activation mechanism by ultra-low frequency magnetic field and development of minimally invasive therapy
- 2020 - 2023 Pathological analysis of limb girdle congenital myasthenia and development of new therapy
- 2017 - 2021 Pathological analysis of GFPT1 congenital myasthenia and development of new therapy using iPS cells.
- 2019 - 2020 先天性筋無力症候群における分子病態の解明と新規治療法の開発
- 2019 - 2020 iPS 細胞を用いた先天性筋無力症候群の病態解析および新規治療法の開発
- 2018 - 2019 腸内細菌叢の変動によるパーキンソン病発症機序の解明と発症抑制・病態進行抑制法の開発
- 2016 - 2017 パーキンソン病患者の腸内細菌層(マイクロバイオーム)解析による病態解明
- 2013 - 2017 筋ジストロフィーにおける細胞外分子補充療法の開発
- 2015 - 2016 パーキンソン病の発症と病態進行に関わる腸内細菌叢の解明
- 2012 - 2015 神経筋接合部の正常構築と分子病態研究(大野欽司)
- 2011 - 2013 重症筋無力症における抗MuSK抗体の認識分子同定
- 2012 - 2013 筋ジストロフィーにおける細胞外分子biglycan補充療法の開発
- 2010 - 2012 Molecular mechanisms underlying the effects of molecular hydrogen on health promotion and disease control
- 2009 - 2011 骨格筋細胞外分子欠損症における、組織標的シグナルを利用した汎用治療法の開発研究
- 2009 - 2011 Analysis of mRNA metabolisms and therapeutic interventions for defects in neuromuscular signal transduction
- 2009 - 2010 骨格筋細胞外分子欠損症における、組織標的シグナルを利用した汎用治療法の開発研究
- 2007 - 2009 神経筋接合部信号伝達障害に対するタンパク標的治療法の開発研究
- 2006 - 2006 神経筋接合部の先天的分子欠損症に対するタンパク標的治療法の開発
- アラビドプシスにおけるメチル化DNA結合タンパク質の解析
- Analysis of methylated DNA binding protein in Arabidopsis
Show all
Papers (104):
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Masaki Teranishi, Mikako Ito, Zhizhou Huang, Yuki Nishiyama, Akio Masuda, Hiroyuki Mino, Masako Tachibana, Toshiya Inada, Kinji Ohno. Extremely Low-Frequency Electromagnetic Field (ELF-EMF) Increases Mitochondrial Electron Transport Chain Activities and Ameliorates Depressive Behaviors in Mice. International Journal of Molecular Sciences. 2024. 25. 20. 11315-11315
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Yuichi Miyairi, Bisei Ohkawara, Ayato Sato, Ryusuke Sawada, Hisao Ishii, Hiroyuki Tomita, Taro Inoue, Hiroaki Nakashima, Mikako Ito, Akio Masuda, et al. A class of chemical compounds enhances clustering of muscle nicotinic acetylcholine receptor in cultured myogenic cells. Biochemical and biophysical research communications. 2024. 731. 150400-150400
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Ruchen Zhang, Paniz Farshadyeganeh, Bisei Ohkawara, Kazuki Nakajima, Jun-Ichi Takeda, Mikako Ito, Shaochuan Zhang, Yuki Miyasaka, Tamio Ohno, Madoka Mori-Yoshimura, et al. Muscle-specific lack of GFPT1 in knock-in mice triggers ER stress to alleviate misfolded proteins. Disease models & mechanisms. 2024
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Masako Tachibana, Toshiya Inada, Hiroki Kimura, Mikako Ito, Yachiyo Kuwatsuka, Fumie Kinoshita, Daisuke Mori, Kinji Ohno. Extremely Low Frequency, Extremely Low Magnetic Environment for depression: An open-label trial. Asian journal of psychiatry. 2024. 96. 104036-104036
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Hiroshi Nishiwaki, Jun Ueyama, Mikako Ito, Tomonari Hamaguchi, Keiichi Takimoto, Tetsuya Maeda, Kenichi Kashihara, Yoshio Tsuboi, Hiroshi Mori, Ken Kurokawa, et al. Meta-analysis of shotgun sequencing of gut microbiota in Parkinson's disease. NPJ Parkinson's disease. 2024. 10. 1. 106-106
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MISC (27):
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西脇 寛, 伊藤 美佳子, 石田 智大, 浜口 知成, 前田 哲也, 柏原 健一, 坪井 義夫, 上山 純, 島村 鉄平, 森 宙史, et al. パーキンソン病患者の腸内細菌叢異常のメタ分析と予後因子. 腸内細菌学雑誌. 2020. 34. 2. 113-113
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片岡直行, 伊藤美佳子, 増田章男, 大野欽司, 江口加代子, 伯野史彦, 高橋伸一郎, 中山恒. 低酸素条件下における選択的スプライシング機構の解明. 日本RNA学会年会要旨集. 2019. 21st
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Kinji Ohno, Bisei Ohkawara, Mikako Ito. Agrin-LRP4-MuSK signaling as a therapeutic target for myasthenia gravis and other neuromuscular disorders. EXPERT OPINION ON THERAPEUTIC TARGETS. 2017. 21. 10. 949-958
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Kinji Ohno, Bisei Ohkawara, Mikako Ito. Recent advances in congenital myasthenic syndromes. Clinical and Experimental Neuroimmunology. 2016. 7. 3. 246-259
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Mikako Ito, Yumi Suzuki, Takashi Okada, Takayasu Fukudome, Toshiro Yoshimura, Akio Masuda, Shin'ichi Takeda, Eric Krejci, Kinji Ohno. PROTEIN-ANCHORING THERAPY FOR DELIVERING ACETYLCHOLINESTERASE TO THE NEUROMUSCULAR JUNCTION. JOURNAL OF GENE MEDICINE. 2014. 16. 7-8. 271-272
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Books (5):
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生物の科学遺伝 63ー5 タンパク質係留治療
エヌ・ティー・エス 2009 ISBN:4860432819
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「クロモソーム植物染色体研究の方法」福井希一、向井康比己、谷口研至編著 アラビドプシスにおける染色体観察方法
養賢堂 2006
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細胞工学別冊 植物細胞工学シリーズ13「植物細胞の分裂」シロイヌナズナ染色体の識別・同定(共著)
秀潤社 2000
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植物細胞工学シリーズ13「植物細胞の分裂」町田康則、福田泰穂監修 シロイヌナズナ染色体の識別・同定
秀潤社 2000
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クロモソーム植物染色体研究の方法「アラビドプシスにおける染色体観察方法」
2006
Lectures and oral presentations (7):
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Protein-anchoring therapy for delivering acetylcholinesterase to the neuromuscular junction
(11th International Meeting on Cholinesterases (Poster), Kazan, Russia 2012)
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Protein-anchoring therapy For delivering acetylcholinesterase to the neuromuscular junction
(17th Annual Meeting of the Japan Society of Gene Therapy (Poster), Fukuoka, Japan 2011)
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分子状水素はパーキンソン病モデルラットの発症を抑制し、ヒト筋疾患の各種マーカーを改善する
(日本分子生物学会 神戸 ワークショップ 2010)
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rAAV8-Mediated Protein-Anchoring Therapy for Targeting Collagen Q-Tailed Acetylcholinesterase to the Neuromuscular Junction
(American Society of Gene & Cell Therapy 13th Annual Meeting (Platform), Washington DC, USA 2010)
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rAAV8-mediated protein anchoring of asymmetric acetylcholinesterase (AChE) to the synaptic basal lamina at the neuromuscular junction (NMJ)
(48th Annual Meeting of the American Society for Cell Biology (Poster), San Francisco, San Diego, California, USA 2008)
more...
Education (2):
- - 2001 Osaka University
- - 1996 Chiba University Faculty of Horticulture
Professional career (1):
Work history (7):
Association Membership(s) (3):
日本生化学会
, 日本筋学会
, The molecular biology society of Japan
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