Rchr
J-GLOBAL ID：200901004178498910   Update date: Nov. 01, 2024

Okada Taro

オカダ タロウ | Okada Taro
Affiliation and department：
Kobe University Graduate School of Medicine Faculty of Medical Sciences

About Kobe University Graduate School of Medicine Faculty of Medical Sciences


Job title： Associate Professor
Research field  (5)： Molecular biology ,  Functional biochemistry ,  Neuroscience - general ,  Medical biochemistry ,  Cell biology
Research keywords  (3)： 細胞生物学 ,  signal transduction ,  sphingosine kinase
Research theme for competitive and other funds  (23)：
  • 2022 - 2025 シヌクレイノパチーにおける細胞外αシヌクレインによる新規病変伝播機構の解明
  • 2018 - 2021 パーキンソン病の病態におけるS1P受容体シグナルおよびエキソソーム放出の関与
  • 2018 - 2021 S1Pシグナルを介したエキソソーム放出の分子機構の解析
  • 2018 - 2020 S1Pシグナルを介したパーキンソン病の病態解析
  • 2015 - 2018 細胞外α-シヌクレインによるS1P受容体シグナル伝達抑制機構の解析
Show all
Papers (47)：
  • Susumu Nishida, Shubi Ambwene Matovelo, Taketoshi Kajimoto, Shun-Ichi Nakamura, Taro Okada. Involvement of sphingosine 1-phosphate signaling in insulin-like growth factor-II/mannose 6-phosphate receptor trafficking from endosome to the trans-Golgi network. Communications biology. 2024. 7. 1. 1182-1182
  • Susumu Nishida, Shubi Ambwene Matovelo, Taketoshi Kajimoto, Shun-Ichi Nakamura, Taro Okada. Extracellular α-synuclein impairs sphingosine 1-phosphate receptor type 3 (S1PR3)-regulated lysosomal delivery of cathepsin D in HeLa cells. Genes to cells : devoted to molecular & cellular mechanisms. 2024. 29. 3. 207-216
  • Nana Sakakibara, Takeshi Ijuin, Tomoko Horinouchi, Tomohiko Yamamura, China Nagano, Eri Okada, Shinya Ishiko, Yuya Aoto, Rini Rossanti, Takeshi Ninchoji, et al. Identification of novel OCRL isoforms associated with phenotypic differences between Dent disease-2 and Lowe syndrome. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 2022. 37. 2. 262-270
  • Taro Okada, Susumu Nishida, Lifang Zhang, Nesma Nabil Ibrahim Mohamed, Tianyou Wang, Takeshi Ijuin, Taketoshi Kajimoto, Shun-Ichi Nakamura. Constitutive activation of S1P receptors at the trans-Golgi network is required for surface transport carrier formation. iScience. 2021. 24. 11. 103351-103351
  • Shubi Ambwene Matovelo, Lifang Zhang, Nesma Nabil Ibrahim Mohamed, Taketoshi Kajimoto, Takeshi Ijuin, Taro Okada, Shun-Ichi Nakamura. Involvement of Receptor-Mediated S1P Signaling in EGF-Induced Macropinocytosis in COS7 Cells. The Kobe journal of medical sciences. 2020. 66. 3. E94-E101
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MISC (7)：
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Lectures and oral presentations  (40)：
  • 脂肪族アルデヒドの代謝異常がゲノム安定性に及ぼす影響
    (日本環境変異原ゲノム学会第53回大会 2024)
  • アルデヒド脱水素酵素ALDH3A2の欠損がゲノム安定性維持に及ぼす影響の解析
    (第47回日本分子生物学会年会 2024)
  • 脂質代謝過程で生じるアルデヒドのゲノム安定性維持における影響
    (日本環境変異原ゲノム学会 2023)
  • SphK1/S1P受容体系はエンドソームからTGNへのCI-M6PRの逆行輸送に寄与することでライソゾーム酵素Cathepsin Dの活性を制御する
    (第96回日本生化学会大会 2023)
  • Effect of extracellular alpha-synuclein on S1P receptor
    (2022)
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Education (1)：
  • - 1996 The University of Tokyo Graduate School of Pharmaceutical Science Doctoral Program
Professional career (2)：
  • 修士(薬学) (東京大学)
  • 博士(薬学) (東京大学)
Committee career (1)：
  • 2019/04 - 現在 スフィンゴテラピィ研究会 組織委員
Association Membership(s) (2)：
スフィンゴテラピィ研究会 ,  日本生化学会
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