Rchr
J-GLOBAL ID：200901004250273570
Update date: Nov. 05, 2024
Ohta Keisuke
オオタ ケイスケ | Ohta Keisuke
Affiliation and department：
Job title：
Professor
Other affiliations (1)：
Homepage URL (1)：
http://airc.kurume-u.ac.jp
Research field (6)：
Cell biology
, Cell biology
, Nanobioscience
, Morphology, anatomy
, Anatomy
, Neuroanatomy and physiology
Research keywords (11)：
CLEM correlative light electron microscopy
, Array tomography
, Structual biology
, 三次元解析
, SEM
, mitochondria
, actin bundle
, electron tomography
, 3D electron microscope
, FIB
, Histochemistry
Research theme for competitive and other funds (24)：
- 2022 - 2028 Advanced Bioimaging Support
- 2023 - 2026 Correlative observation of contact site of mitochondria and endoplasmic reticulum between light microscopy and electron microscopy
- 2023 - 2026 Creation of Nanomulti sensitization cascade radiotherapy against the cytoskeleton and intracellular organelles
- 2020 - 2023 Three dimensional ultrastructural analyses of the distribution pattern and dynamics of the interstitial cells in the connective tissues in the mammalian body.
- 2020 - 2023 Development of hyperthermia radiation multi-theranostics nanoparticles highly accumulated in malignant melanoma
- 2020 - 2023 Mitochondrial shape determination mechanism with phosphorylation and dephosphorylation process
- 2016 - 2019 Development of Class Lesson Model based on Learning through Discussion
- 2015 - 2019 The function and relationship between interstitial cells in the detrusor bundle and smooth muscle cells
- 2015 - 2018 Advanced 3D analysis of the stromal cells interaction and formed network following acute muscle trauma by the FIB/SEM observation.
- 2015 - 2018 Three dimensional ultrastructural background of mitochondrial dynamics using novel CLEM method
- 2015 - 2018 Observation of corneal and scleral fibroblast network by using FIB/SEM
- 2015 - 2018 Analysis of scars and keloids using a focused ion beam/scanning electron microscope differentiation between hypertrophic scars and keloids
- 2014 - 2018 Development of comprehensive mapping method of target molecule linked with cell division process
- 2014 - 2017 Three dimensional ultrastructural analysis of fibroblasts and their cellular network in the connective tissue by FIB/SEM tomography
- 2014 - 2017 Development of new cell field structure technology to elucidate the basic mechanism of eukaryotes
- 2013 - 2017 A new strategy for the treatment of rett syndrome with ghrelin and bone marrow transplantation
- 2013 - 2015 The three dimensional fine structural analysis of ICC by FIB/SEM tomography
- 2012 - 2015 Pathological relevance of spatial relationships between dermal macrophages and fibroblasts by new generation structome analysis
- 2012 - 2012 ptimization of FIB/SEM techniques ? the novel ultrastructureeanalysis by combination of serial thin ablation and block surface material contrastobservation - for biomedical mesoscale three dimentional structural analysis.
- 2007 - 2008 Histological and ultrastructural examination of the GFP labeled-bone marrow derived cells
- 2004 - 2005 細胞内シグナル伝達系遺伝子変異による新たな消化管運動障害モデルの検討
- 2003 - 2004 生体内で軸索末端に投与された神経栄養因子に反応する神経細胞体の同定法開発
- 2001 - 2002 神経栄養因子BDNFの、脊髄神経節より脊髄後索に入る突起における作用
- 1999 - Study of the mode of transport and the mechanisms of signal transduction of neurotrophic factors in peripheral nervous tissue
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Papers (99)：
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Kazuaki Mori, Akinobu Togo, Kota Yamashita, Taishi Umezawa, Keisuke Ohta, Toru Asahi, Chihiro Nozaki, Kosuke Kataoka. Mitochondrial Dysfunction and ER Stress in CB1 Receptor Antagonist-Induced Apoptosis in Human Neuroblastoma SH-SY5Y Cells. 2024
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Kei-Ichiro Uemura, Akinobu Togo, Tasuku Hiroshige, Keisuke Ohta, Kosuke Ueda, Kiyoaki Nishihara, Makoto Nakiri, Shingo Hirashima, Tsukasa Igawa, Kei-Ichiro Nakamura. Three-dimensional ultrastructural and anatomical analysis of prostatic neuroendocrine cells in mice. The Prostate. 2024. 84. 9. 866-876
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Magdeline E. Carrasco Apolinario, Ryohei Umeda, Hitoshi Teranishi, Mengting Shan, Phurpa, Wulan Apridita Sebastian, Shaohong Lai, Nobuyuki Shimizu, Hiroshi Shiraishi, Kenshiro Shikano, et al. Behavioral and neurological effects of Vrk1 deficiency in zebrafish. Biochemical and Biophysical Research Communications. 2023. 675. 10-18
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Satoko Kurata, Aya Nawata, Takuya Morinishi, Keisuke Ohta, Eisuke Katafuchi, Satoshi Hisano, Seiji Tanaka, Masanori Hisaoka, Junki Koike, Ryuta Nishikomori, et al. Immunoglobulin G deposition on proximal tubules and the tubular basement membrane in acute tubular injury complicated with focal segmental glomerulosclerosis (FSGS): A possible prediction tool for subclinical FSGS. Annals of Diagnostic Pathology. 2023. 66. 152154-152154
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Mami Nomura, Keisuke Ohta, Yukinori Nishigami, Takuro Nakayama, Kei-Ichiro Nakamura, Kenjiro Tadakuma, Josephine Galipon. Three-dimensional architecture and assembly mechanism of the egg-shaped shell in testate amoeba Paulinella micropora. Frontiers in Cell and Developmental Biology. 2023. 11
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MISC (52)：
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Hisashi Migita, Hideaki Rikimaru, Yukiko Rikimaru-Nishi, Noriyuki Koga, Koichi Watanabe, Keisuke Ohta, Kei-Ichiro Nakamura, Kensuke Kiyokawa. Analysis of Scars and Keloids by Focused Ion Beam/Scanning Electron Microscopy: Distinguishing Between Hypertrophic Scars and Keloids. Annals of plastic surgery. 2020. 84. 4. 379-384
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広重佑, 上村慶一郎, 平嶋晋吾, 都合亜記暢, 太田啓介, 太田啓介, 中村桂一郎, 井川掌. Three-dimensional ultrastructural analysis of PDGFRα-positive interstitial cells in the mammalian vas deferens by FIB/SEM tomography. 西日本泌尿器科. 2020. 82
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右田 尚, 力丸 由起子, 古賀 憲幸, 太田 啓介, 中村 桂一郎, 清川 兼輔. ケロイドの新たな診断と治療法 肥厚性瘢痕とケロイドの電子顕微鏡による三次元解析. 日本創傷治癒学会プログラム・抄録集. 2017. 47回. 102-102
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太田 啓介, 金澤 知之進, 力丸 由起子, 平嶋 伸悟, 安永 悟, 中村 桂一郎. アクティブ・ラーニングの実践例の紹介 医学部組織学実習へのLTD基盤型授業を意識した協同学習の導入とその効果. 医学教育. 2017. 48. Suppl. 13-13
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鴻崎 香里奈, 竹垣 淳也, 田村 優樹, 小林 正利, 中村 桂一郎, 太田 啓介, 中里 浩一. デュシェンヌ型筋ジストロフィーモデルラットにおける筋機能と骨格筋内ミトコンドリアの特徴. 日本筋学会学術集会プログラム・抄録集. 2017. 3回. 76-76
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Lectures and oral presentations (7)：
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Imaging Technology Bridging Macro-scale to Nanometer-scale The Latest Light Electron Correlative Microscopy (CLEM)
(The 81st Annual Meeting of the Japanese Cancer Association 2022)
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Micro Volume Imaging
(2022)
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Practical CLEM approach using SEM
(The 78th annual meeting of the Japanese Society of Microscopy 2022)
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真皮内異種間細胞性コンタクトの光電子相関(CLEM)観察
(第128回日本解剖学会全国学術集会 2022)
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エポキシ樹脂準超薄切片におけるコンゴーレッド染色によるアミロイドCLEM観察
(第127回日本解剖学会全国学術集会 2022)
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Education (2)：
- 1991 - 1993 Kyushu Univ.
- 1987 - 1991 Synsyu Univ. Faculty of FIber Applied Bioscience
Professional career (2)：
- Ph.,D. (Kurume University)
- Master (Kyushu University)
Work history (9)：
- 2019/07 - 現在 Kurume University School of Medicine Deptertment of Anatomy Professor
- 2019/07 - 現在 Kurume University School of Medicine Advanced Imaging Research Center Professor
- 2018/04 - 現在 RIKEN
- 2017/06 - 2019/06 Kurume Univ. Sch. Med. Advanced Imaging Research Center Associate Prof.
- 2011/08 - 2019/06 Kurume Univ. Sch. Med. Dept. Anat. Div. Microscopic & Developmental Anatomy Associate Prof.
- 2013/11 - 2018/03 RIKEN
- 2002/10 - 2011/07 Kurume University School of Medicine
- 1993/03 - 2002/09 Kurume University School of Medicine
- 1993 - - Kurume University, Research Assistant
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Committee career (6)：
- 2021/04 - 現在 日本電子顕微鏡学会 電子顕微鏡技術認定 委員長
- 2020/05 - 現在 日本顕微鏡学会誌「顕微鏡」編集委員会 委員
- 2017/05 - 現在 日本顕微鏡学会 ソフトマテリアル研究部会 幹事
- 2014 - 現在 日本顕微鏡学会 技術認定委員会 委員
- 2018/05 - 2020/05 日本顕微鏡学 会将来構想委員会 委員
- 2013/05 - 2015/05 Study group on three dimensional reconstruction of cell and tissue by serial slice scanning electron microscopy Chair
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Association Membership(s) (3)：
日本組織細胞化学会
, 日本顕微鏡学会
, 日本解剖学会
