Aoki-Shioi Narumi

シオイ(アオキ) ナルミ | Aoki-Shioi Narumi

Affiliation and department：
Job title： Lecture

Research field (7)： Environmental and pharmaceutical development resources , Bioorganic chemistry , Pharmaceuticals - chemistry and drug development , Social-ecological systems , Ecology and environmental science , Biochemistry , Functional biochemistry

Research keywords (8)：植物由来のシステインリッチタンパク質の多様性 , Natural products-Bioactive compounds- , Evolution in venomous animals , Enzyme regulation , 突然変異と多様性 , 毒素科学 , Inhibitor , snake venom

Research theme for competitive and other funds (21)：

2023 - 2026 ヘビ毒液の相乗効果機構を含む毒素活性制御システムの解析
2023 - 2025 植物由来セリンプロテアーゼインヒビターを基盤とした機能性ペプチドの創出基盤技術研究
2023 - 2024 コブラの毒を無毒化する分子機構の解明
2020 - 2023 Rational design of selective inhibitors targeting snake venom based on resistance system of venomous snake
2023 - 「ひらめき☆ときめきサイエンス~KAKENHI」毒ヘビ編;世界のヘビについて知ろう

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Papers (40)：

Kazuki Matsubara, Shouta Ueda, Junpei Yamamoto, Shigenori Iwai, Narumi Aoki Shioi, Arato Takedachi, Isao Kuraoka. Structure-specific DNA endonuclease T7 endonuclease I cleaves DNA containing UV-induced DNA lesions. The Journal of Biochemistry. 2024
Narumi Aoki-Shioi, Yuki Nagai, Masanobu Deshimaru, Shigeyuki Terada. Precursor genes of Bowman-Birk-type serine proteinase inhibitors comprise multiple inhibitory domains to promote diversity. Biochimica et Biophysica Acta (BBA) - General Subjects. 2023. 1867. 1. 130248-130248
Megumi Endo, Jung In Kim, Narumi Aoki-Shioi, Shigenori Iwai, Isao Kuraoka. Arabidopsis thaliana endonuclease V is a ribonuclease specific for inosine-containing single-stranded RNA. Open Biology. 2021. 11. 10. 210148-210148
Yaopeng Hu, Qin Li, Lin-Hai Kurahara, Narumi Shioi, Keizo Hiraishi, Takayuki Fujita, Xin Zhu, Ryuji Inoue. An Arrhythmic Mutation E7K Facilitates TRPM4 Channel Activation via Enhanced PIP2 Interaction. Cells. 2021. 10. 5. 983-983
Narumi Aoki-Shioi, Shigeyuki Terada, Roland Hellinger, Yoshitaka Furuta, Christian W. Gruber. Isolation and functional diversity of Bowman-Birk type serine proteinase inhibitors from Hyacinthus orientalis. Biochemical Journal. 2021. 478. 6. 1287-1301

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MISC (8)：

田所高志, 岡部由紀, 松原永季, 喜多俊介, 尾瀬農之, 黒木喜美子, 前仲勝実, 寺田成之, 塩井(青木)成留実. 毒ヘビ由来Ca²⁺チャネル阻害型神経毒と毒ヘビ血清蛋白質の複合体構造. 日本結晶学会年会講演要旨集. 2021. 2021
Ayaka Ogura, Yoshifumi Zaitsu, Keizo Hiraishi, Isao Kuraoka, R. Manjunatha Kini, Narumi Shioi Aoki. RATIONAL DESIGN AND DEVELOPMENT OF ANTI-VENOM DRUGS FOR SNAKEBITES BASED ON THE ENDOGENOUS INHIBITORS FROM JAPANESE VIPER. TOXICON. 2019. 159. S10-S10
Narumi Shioi, Takashi Tadokoro, Yaopeng Hu, Lin Hai Kurahara, Keizo Hiraishi, Katsumi Maenaka, Isao Kuraoka, Shigeyuki Terada. SPECIFICITY OF ENDOGENOUS INHIBITOR FOR THE SNAKE NEUROTOXIN TRIFLIN: INTERACTION AND STRUCTURE ANALYSIS. TOXICON. 2019. 158. S34-S34
田所高志, 塩井(青木, 成留実, 岡部由紀, 松原永季, 喜多俊介, 尾瀬農之, 黒木喜美子, 前仲勝実, 寺田成之. 毒ヘビ由来Ca2+チャネル阻害型神経毒と毒ヘビ血清蛋白質の複合体構造. 日本蛋白質科学会年会プログラム・要旨集. 2018. 18th. 90
塩井成留実, 田所高志, 胡耀鵬, 倉原琳, 平石敬三, 前仲勝実. ハブ血清蛋白質SSPの毒蛇CRISPsの阻害剤としての応用. トキシンシンポジウム予稿集. 2017. 64th. 76-79

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Books (5)：

女性のエンパワーメントガラスの天井を越えて (社会問題) Kindle Edition
Kindle 2023
あすばる~んNo.108春号女性はもっと活躍できる理工系分野での男女共同参画
福岡県男女共同参画センター「あすばる」 2023
Snakebite Therapeutics Based on Endogenous Inhibitors from Vipers
IntechOpen 2019
魅惑的な毒をもつ生物研究へのお誘い
羊土社、実験医学 2018
ヘビの毒について
七隈の杜2015 (Nanakumano-mori NO.11 2015) 2015

Lectures and oral presentations (12)：

Crystal structure of synergistic-type toxin from Dendroaspis (mamba) venom shows a unique quaternary structure of three finger toxin family
(21st World Congress of the International Society on Toxinology (IST) 2022)
Synergistic toxins from mamba snake venom; structural insight into evolution of tree finger toxin family
(2022)
Identification of inhibitory regions of Small serum protein-4 (SSP-4) against vascular apoptosis-inducing snake venom metalloprotease
(The 11th Asia-Pacific Congress of the International Society on Toxinology 2021 2021)
日本人女性研究者の意識改革 -海外の女性研究者たちは-
(日本糖質学会 2021)
Regulation system of snake toxin proteins
(2019)

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Professional career (1)：

博士(理学) (福岡大学)

Work history (1)：

2008/04 - 2023/03 Fukuoka University Faculty of Science Department of Chemistry Assistant Professor

Committee career (4)：

2023/02 - Organizing Committee Member of IST World Congress 2024
2023 - 2023 The Japanese Environmental Mutagen and Genome Society (JEMS) Executive Committee 2023
2013/12 - 2015/12 毒素シンポジウム学会毒素シンポジウム学会運営委員
2012 - 2012 The Japanese Biochemical Society Executive Committee 2012

Awards (5)：

2021/11 - Genes and Environment Genes and Environment 2020 Best Paper Award Effects of acetaldehyde-induced DNA lesions on DNA metabolism
2019/09/13 - 20th World Congress of the International Society on Toxinology TOXICON Best Poster Award Developing towards anti-venom drugs by endogenous inhibitor against the metalloproteinase induced hemorrhage; rational design of drug and therapeutic potential for snakebite
2019/06 - 日本生化学会九州支部学術奨励賞受賞講演
2017/11 - The 12th International conference & 5th ASIAN congress on environmental mutagens BEST PRESENTATION AWARD
2012/08/31 - 第59回毒素シンポジウム研究毒素シンポジウム若手奨励賞毒ヘビの生体防御物質に関する

Association Membership(s) (6)：

毒素シンポジウム学会 , 日本生化学会 , 日本農芸化学会 , 日本蛋白質科学会 , 日本ペプチド学会 , 日本化学会

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