Research theme for competitive and other funds (11)：
2023 - 2026 Regulation of insulin-like activities using signaling complexes formed by RNA and IRS-1.
2022 - 2025 The study on the physiological role of the increase in hepatic insulin receptor substrate-2 under protein deprivation
2022 - 2025 Elucidation of the endpoint of the tryptophan signal that stimulates hepatic protein synthesis
2019 - 2022 Study on the mechanisms by which the translation initiation regulating factors induces lipid accumulation in rat liver under protein deprivation.
2016 - 2019 The physiological significance of eukaryotic translation initiation factor 4E-binding protein 1 (4E-BP1) on lipid accumulation in rat liver under protein deprivation.
2013 - 2016 The mechanisms by which protein malnutrition increases circulating adiponectin levels in rats
2009 - 2011 Mechanism of the enhancement of hepatic insulin action induced by protein malnutrition
Tomoko Nakata, Yoshitaka Hirano, Harumi Katsumata, Reiko Tokita, Takashi Yagi, Yuka Toyoshima, Shiro Minami. Growth hormone activates x-box binding protein 1 in a sexually dimorphic manner through the extracellular signal-regulated protein kinase and ccaat/enhancer-binding protein β pathway in rat liver. Endocrine Journal. 2020. 67. 2. 185-200
An increase in 4E-BP1 level mediates to enhance triglyceride accumulation in rat liver under protein malnutrition
(IUNS 21st ICN International Congress of Nutrition 2017)
Protein malnutrition increases the amount and phosphorylation of 4E-binding protein 1 (4E-BP1) to accumulate lipid in rat liver.
(12th Asian Congress of Nutrition 2015)
