Rchr
J-GLOBAL ID:200901004981960215   Update date: Jan. 30, 2024

Nameki Nobukazu

ナメキ ノブカズ | Nameki Nobukazu
Affiliation and department:
Homepage URL  (1): http://molbio.chem-bio.st.gunma-u.ac.jp/
Research field  (1): Molecular biology
Research keywords  (7): Stalled riboosome rescue ,  RNA ,  NMR構造解析 ,  タンパク質機能解析 ,  RNA ,  NMR構造解析 ,  タンパク質機能解析
Research theme for competitive and other funds  (14):
  • 2021 - 2025 翻訳停滞解消因子YaeJの生理的役割と反応機構の解明
  • 2020 - 2021 翻訳停滞解消不全によるミトコンドリア病の病態発現機構の解明と治療基盤研究
  • 2015 - 2017 ミトコンドリアにおける翻訳停滞解消機構およびその不全による病態発現機構の解明
  • 2013 - 2016 Analysis of the pathological mechanism of NASH by the nuclear receptors and establishment of the therapeutic application
  • 2012 - 2016 Stabilizing endocrine cell function by phogrin.
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Papers (62):
  • Nobukazu Nameki, Shin-ichi Terawaki, Masayuki Takizawa, Madoka Kitamura, Yutaka Muto, Kanako Kuwasako. Structural insights into recognition of SL4, the UUCG stem-loop, of human U1 snRNA by the ubiquitin-like domain, including the C-terminal tail in the SF3A1 subunit of U2 snRNP. The Journal of Biochemistry. 2023
  • Nobukazu Nameki, Masayuki Takizawa, Takayuki Suzuki, Shoko Tani, Naohiro Kobayashi, Taiichi Sakamoto, Yutaka Muto, Kanako Kuwasako. Structural basis for the interaction between the first SURP domain of the SF3A1 subunit in U2 snRNP and the human splicing factor SF1. Protein Science. 2022. 31. 10
  • Kanako Kuwasako, Sakura Suzuki, Nobukazu Nameki, Masayuki Takizawa, Mari Takahashi, Kengo Tsuda, Takashi Nagata, Satoru Watanabe, Akiko Tanaka, Naohiro Kobayashi, et al. 1H, 13C, and 15N resonance assignments and solution structures of the KH domain of human ribosome binding factor A, mtRbfA, involved in mitochondrial ribosome biogenesis. Biomolecular NMR Assignments. 2022
  • Soichiro Hoshino, Ryohei Kanemura, Daisuke Kurita, Yukihiro Soutome, Hyouta Himeno, Masak Takaine, Masakatsu Watanabe, Nobukazu Nameki. A stalled-ribosome rescue factor Pth3 is required for mitochondrial translation against antibiotics in Saccharomyces cerevisiae. Communications Biology. 2021. 4. 1. 300-300
  • 矢島美帆乃, 金村涼平, 小椋義俊, 行木信一. 可動性スーサイドベクターを利用したグラム陰性菌遺伝子欠損株の作製法. 生化学. 2020. 92. 4. 591-596
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MISC (14):
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Books (1):
  • Encyclopedia of Systems Biology
    Springer New York 2013
Lectures and oral presentations  (70):
  • 翻訳停滞解消因子YaeJの発現制御機構の解明
    (第42回日本分子生物学会年会)
  • 酵母ミトコンドリアにおける抗生物質に起因する翻訳停滞の解消機構の解明
    (第21回日本RNA学会年会)
  • Proteomic analysis of stalled-ribosome rescue factor-deficient strains of Saccharomyces cerevisiae by two-dimensional gel electrophoresis
    (5th International Symposium of Gunma University Medical Innovation (GUMI2018) 2018)
  • Functional analysis of two stalled-ribosome rescue factors in mammalian and yeast mitochondria
    (4th International Symposium of Gunma University Medical Innovation (GUMI2017) 2017)
  • 大腸菌yaeQ-yaeJ-nlpEオペロンの内部プロモーターの機能解析
    (第39回日本分子生物学会年会 2016)
more...
Education (2):
  • - 1997 Graduate School of Science, The University of Tokyo Faculty of Science Department of Physics
  • - 1990 The University of Tokyo Faculty of Science Department of Physics,
Professional career (1):
  • Ph.D. (The University of Tokyo)
Work history (7):
  • 2005 - 現在 Graduate School of Science and Technology, Gunma University Division of Molecular Science
  • 2002 - 2005 理化学研究所 ゲノム科学総合研究センタ-(GSC) 研究員
  • 2000 - 2002 日本学術振興会 研究員(千葉工業大学)
  • 1998 - 2000 Tokyo Institute of Technology Graduate School of Bioscience and Biotechnology
  • 1996 - 1998 日本学術振興会 特別研究員(弘前大学)
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Association Membership(s) (3):
日本生化学会 ,  日本RNA学会 ,  分子生物学会
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