Rchr
J-GLOBAL ID:200901004981960215
Update date: Jan. 30, 2024
Nameki Nobukazu
ナメキ ノブカズ | Nameki Nobukazu
Affiliation and department:
Homepage URL (1):
http://molbio.chem-bio.st.gunma-u.ac.jp/
Research field (1):
Molecular biology
Research keywords (7):
Stalled riboosome rescue
, RNA
, NMR構造解析
, タンパク質機能解析
, RNA
, NMR構造解析
, タンパク質機能解析
Research theme for competitive and other funds (14):
- 2021 - 2025 翻訳停滞解消因子YaeJの生理的役割と反応機構の解明
- 2020 - 2021 翻訳停滞解消不全によるミトコンドリア病の病態発現機構の解明と治療基盤研究
- 2015 - 2017 ミトコンドリアにおける翻訳停滞解消機構およびその不全による病態発現機構の解明
- 2013 - 2016 Analysis of the pathological mechanism of NASH by the nuclear receptors and establishment of the therapeutic application
- 2012 - 2016 Stabilizing endocrine cell function by phogrin.
- 2012 - 2015 Study on the controlling mechanism of fibrin gel formation by the unordered region of fibrinogen and N-linked saccharide chain
- - 2014 酵母を利用した翻訳過程不全によるミトコンドリア病の分子メカニズムの研究
- - 2014 ミトコンドリアにおける翻訳停滞解消機構およびその不全による病態発現機構の解明
- 2011 - 2013 翻訳が滞ったリボソームのtmRNA非依存的な新規レスキュー機構の解析
- 2010 - 2012 Study of the nuclear receptors involved in fatty livers; establishment of a new pathological model and development of therapeutic application.
- 2009 - 2011 Mechanism analysis of sulfobetaines' activity to prevent protein aggregation and application of sulfobetaines to unstable proteins
- - 2011 翻訳停滞解消機構の導入による無細胞蛋白質合成系の改良
- - 2008 配列特異性をもたせたタンパク質凝集防止剤の開発
- 2000 - 2000 古細菌tRNAに特異的な修飾ヌクレオシド・アーケオシの生合成機構と機能の解明
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Papers (62):
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Nobukazu Nameki, Shin-ichi Terawaki, Masayuki Takizawa, Madoka Kitamura, Yutaka Muto, Kanako Kuwasako. Structural insights into recognition of SL4, the UUCG stem-loop, of human U1 snRNA by the ubiquitin-like domain, including the C-terminal tail in the SF3A1 subunit of U2 snRNP. The Journal of Biochemistry. 2023
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Nobukazu Nameki, Masayuki Takizawa, Takayuki Suzuki, Shoko Tani, Naohiro Kobayashi, Taiichi Sakamoto, Yutaka Muto, Kanako Kuwasako. Structural basis for the interaction between the first SURP domain of the SF3A1 subunit in U2 snRNP and the human splicing factor SF1. Protein Science. 2022. 31. 10
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Kanako Kuwasako, Sakura Suzuki, Nobukazu Nameki, Masayuki Takizawa, Mari Takahashi, Kengo Tsuda, Takashi Nagata, Satoru Watanabe, Akiko Tanaka, Naohiro Kobayashi, et al. 1H, 13C, and 15N resonance assignments and solution structures of the KH domain of human ribosome binding factor A, mtRbfA, involved in mitochondrial ribosome biogenesis. Biomolecular NMR Assignments. 2022
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Soichiro Hoshino, Ryohei Kanemura, Daisuke Kurita, Yukihiro Soutome, Hyouta Himeno, Masak Takaine, Masakatsu Watanabe, Nobukazu Nameki. A stalled-ribosome rescue factor Pth3 is required for mitochondrial translation against antibiotics in Saccharomyces cerevisiae. Communications Biology. 2021. 4. 1. 300-300
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矢島美帆乃, 金村涼平, 小椋義俊, 行木信一. 可動性スーサイドベクターを利用したグラム陰性菌遺伝子欠損株の作製法. 生化学. 2020. 92. 4. 591-596
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MISC (14):
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HAGIHARA Mamoru, TAKEI Ayaka, WAKAMATSU Kaori, NAMEKI Nobukazu. Inhibition of Amyloid Formation by Choline-O-Sulfate. 2011. 2010. 165-165
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WAKAMATSU Kaori, TAKEI Ayaka, INAOKA Yoshihiko, XIAN Long, KOBORI Kanako, KATO Seri, MUKAI Hidehito, KOHNO Toshiyuki, NAMEKI Nobukazu. Prevention of peptide aggregation by non-detergent sulfobetaines (NDSBs). Peptide Sci. 2008. 2009. 2008. 121-122
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Kenji Kuboa, Yuka Masuda, Yoshiharu Toyama, Nobukazu Nameki, Nobuo Okumura, Masanori Ochiai. Formation of Recombinant Fibrinogen Lacking alpha C Termini. GELS: STRUCTURES, PROPERTIES, AND FUNCTIONS. 2009. 136. 187-+
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XIANG Long, 石井毅, 細田和男, 大竹佳樹, 行木信一, 井上裕介, 窪田健二, 河野俊之, 若松馨. NDSBによる蛋白質の安定化. 日本蛋白質科学会年会プログラム・要旨集. 2008. 8th
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白澤豊, XIANG Long, 石井毅, 細田和男, 井上裕介, 行木信一, 窪田健二, 楯真一, 河野俊之, 若松馨. NDSBのNMRへの応用と蛋白質の凝集防止機構. 生化学. 2007
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Books (1):
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Encyclopedia of Systems Biology
Springer New York 2013
Lectures and oral presentations (70):
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翻訳停滞解消因子YaeJの発現制御機構の解明
(第42回日本分子生物学会年会)
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酵母ミトコンドリアにおける抗生物質に起因する翻訳停滞の解消機構の解明
(第21回日本RNA学会年会)
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Proteomic analysis of stalled-ribosome rescue factor-deficient strains of Saccharomyces cerevisiae by two-dimensional gel electrophoresis
(5th International Symposium of Gunma University Medical Innovation (GUMI2018) 2018)
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Functional analysis of two stalled-ribosome rescue factors in mammalian and yeast mitochondria
(4th International Symposium of Gunma University Medical Innovation (GUMI2017) 2017)
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大腸菌yaeQ-yaeJ-nlpEオペロンの内部プロモーターの機能解析
(第39回日本分子生物学会年会 2016)
more...
Education (2):
- - 1997 Graduate School of Science, The University of Tokyo Faculty of Science Department of Physics
- - 1990 The University of Tokyo Faculty of Science Department of Physics,
Professional career (1):
- Ph.D. (The University of Tokyo)
Work history (7):
Association Membership(s) (3):
日本生化学会
, 日本RNA学会
, 分子生物学会
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