Rchr
J-GLOBAL ID：200901005665313409   Update date: Jun. 27, 2024

Hotokezaka Yuka

ホトケザカ ユカ | Hotokezaka Yuka
Affiliation and department：
Nagasaki University Department of Orthodontics and Dentofacial Orthopedics, Nagasaki University Graduate School of Biomedical Sciences

About Nagasaki University Department of Orthodontics and Dentofacial Orthopedics, Nagasaki University Graduate School of Biomedical Sciences


Job title： Senior Assistant Professor
Research field  (2)： Surgical dentistry ,  Oral medicine (pathology)
Research keywords  (11)： Apoptosis ,  ER stress ,  細胞死 ,  放射線 ,  低酸素分圧 ,  歯根吸収 ,  アルツハイマー病 ,  骨吸収 ,  Cell Death ,  Ionizing radiation ,  Hypoxia
Research theme for competitive and other funds  (44)：
  • 2024 - 2027 GSK3β阻害による歯根吸収抑制機構の解明-細胞死と破歯細胞活性を標的にして-
  • 2023 - 2026 歯根吸収発症における細胞小器官分解システム関連蛋白の役割
  • 2022 - 2025 低酸素細胞の放射線抵抗性におけるcPLA2の働き
  • 2021 - 2025 口腔がんの進展・転移における低酸素環境下でのcPLA2の働き
  • 2020 - 2025 骨吸収抑制薬剤関連顎骨壊死に対するMRIの役割
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Papers (67)：
  • Yuka Hotokezaka, Takuya Nakamura, Carmen Karadeniz, Hitoshi Hotokezaka, Noriaki Yoshida. Relationship between early stage periodontal ligament compression and orthodontically induced root resorption in rats. Congress of the European Orthodontic Society Abstract Book. 2024. 163
  • Hitoshi Hotokezaka, Yukako Nashiro-Oyakawa, Yuka Hotokezaka, Mariko Funaki-Dohi, Noriaki Yoshida. Inhibition of 12/15-lipoxygenase reduces orthodontically induced root resorption by suppressing hyaline degeneration and subsequent odotoclast differentiation in rats. Congress of the European Orthodontic Society Abstract Book. 2024. 167
  • Takuya Nakamura, Yuka Hotokezaka, Carmen Karadeniz, Hitoshi Hotokezaka, Yuika Ueda-Ichinose, Kie Nishioka-Sakamoto, Noriaki Yoshida. Early-stage periodontal ligament compression predicts orthodontically induced root resorption in rats. The Angle Orthodontist. 2023
  • Mitsunobu Otsuru, Yoshinari Fujiki, Sakiko Soutome, Norio Nakamura, Taro Miyoshi, Tomofumi Naruse, Mizuho Ohnuma, Yuka Hotokezaka, Satoshi Rokutanda, Masahiro Umeda. Risk factors for dental findings of the development of medication-related osteonecrosis of the jaw: Investigation of 3734 teeth in cancer patients receiving high dose antiresorptive agents. Journal of Dental Sciences. 2023. 19. 1. 203-210
  • Yuka Hotokezaka, Ikuo Katayama, Hitoshi Hotokezaka. ATM-associated signalling triggers the unfolded protein response and cell death in response to stress. The 3rd Japan and Australia Meeting on Cell Death 2023 ABSTRACT BOOK. 2023. 66-66
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MISC (53)：
  • 一瀬悠依華, 佛坂斉祉, 宮崎敏博, 森石武史, 佛坂由可, 有薗ケイラ, 中村琢也, 吉田教明. 矯正力による歯根吸収のリチウムによる抑制の組織額的解析-ラットを用いた実験-. 九州矯正歯科学会学術大会、プログラム・抄録集. 2024. 52
  • 名城友香子, 佛坂由可, 佛坂斉祉, 上田-一瀬悠依華, 西岡-坂本紀栄, 舟木真梨子, 中村琢也, 森田幸子, 井野-近藤愛理, 吉田教明. 12/15 - LOX特異的阻害剤による歯根吸収抑制とその作用機序の解明 -ラットを用いた実験-. 九州矯正歯科学会学術大会、プログラム・抄録集. 2024. 51
  • 中村琢也, 佛坂由可, 佛坂斉祉, 坂本紀栄, 名城-親川友香子, 舟木-土肥真梨子, 吉田教明. 矯正力負荷早期における歯根膜腔狭小化と歯根吸収の相関関係. 九州矯正歯科学会学術大会、プログラム・抄録集. 2024. 51
  • リチウムは矯正力負荷初期の短期間投与でも歯根吸収抑制効果を示すのか?. 2024. 53
  • 舟木, 土肥 真梨子, 佛坂 斉祉, 佛坂 由可, 一瀬 悠依華, 坂本 紀栄, 名城, 親川 友香子, 森田 幸子, 中村 琢也, et al. リチウム短期投与の矯正力による歯根吸収抑制効果. 第82回 日本矯正歯科学会学術大会, プログラム ・ 抄録集. 2023. 38-38
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Lectures and oral presentations  (79)：
  • Relationship between early stage periodontal ligament compression and orthodontically induced root resorption in rats
    (99th Congress of the European Orthodontic Society 2024)
  • Inhibition of 12/15-lipoxygenase reduces orthodontically induced root resorption by suppressing hyaline degeneration and subsequent odotoclast differentiation in rats
    (99th Congress of the European Orthodontic Society 2024)
  • 矯正力による歯根吸収のリチウムによる抑制の組織額的解析-ラットを用いた実験-
    (第19回九州歯科矯正歯科学会学術大会 2024)
  • リチウムは矯正力負荷初期の短期間投与でも歯根吸収抑制効果を示すのか?
    (第19回九州歯科矯正歯科学会学術大会 2024)
  • 12/15 - LOX特異的阻害剤による歯根吸収抑制とその作用機序の解明 -ラットを用いた実験-
    (第19回九州矯正歯科学会学術大会 2024)
ｍore...
Education (4)：
  • - 2002 Nagasaki University
  • - 2002 Nagasaki University Graduate School, Division of Dental Research radiology and cancer biology
  • - 1986 Nagasaki University School of Dentistry
  • - 1986 Nagasaki University Faculty of Dentistry
Professional career (1)：
  • Doctor(Dentistry) (Nagasaki University)
Work history (5)：
  • 2007/01 - 現在 Nagasaki University Hospital
  • 2002/10 - 2006/12 Nagasaki University School of Dentistry
  • 2000/05 - 2002/09 Nagasaki University School of Dentistry
  • 1997/12 - 2000/04 USA, New York, Memorial Sloan-Kettering Cancer Center Sloan-Kettering Institute
  • 1992/04 - 1997/11 Nagasaki University School of Dentistry
Committee career (1)：
  • 2022/04 - 現在 日本歯科放射線学会 代議員
Awards (6)：
  • 2024/06 - 99th EUROPEAN ORTHODONTIC SOCIETY CONGRESS Best Poster Award Inhibition of 12/15-lipoxygenase reduces orthodontically induced root resorption by suppressing hyaline degeneration and subsequent odotoclast differentiation in rats
  • 2022/10 - The 81st Annual Meeting of the Japanese Orthodontic Society & The 9th Joint Symposium of the Japanese Orthodontic Society and Korean Association of Ortodontists. 優秀演題賞. Construction of orthodontic anchor screw loosening and effect of fixation by β-TCP.
  • 2021/11 - The 80th Annual Meeting of Japanese Orthodontic Society & The 5th International Congress. The 80th Annual Meeting of Japanese Orthodontic Society & The 5th International Congress優秀演題賞. Enhanced fixation of orthodontic anchor screws using β-TCP-an experiment using rats.
  • 2021/10 - 日本歯科放射線学会優秀論文賞
  • 2013/06 - Dento-Maxillo-Facial Radiology IADMFR. IADMFR-BIR best poster prize. In vitro measurement of apoptotic and non-apoptotic cells using diffusion-weighted MR.
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Association Membership(s) (10)：
日本Cell Death学会 ,  日本口腔外科学会 ,  歯科基礎医学会 ,  日本矯正歯科学会 ,  日本口腔ケア学会 ,  口腔科学会 ,  JAPANESE SOCIETY OF NUCLEAR MEDICINE ,  JAPANESE SOCIETY FOR BONE AND MINERAL RESEARCH ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  JAPANESE SOCIETY FOR ORAL AND MAXILLOFACIAL RADIOLOGY
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