yoshikazu mikami

ミカミヨシカズ | yoshikazu mikami

Affiliation and department：

Research field (3)： Tumor biology , Immunology , Anatomy

Research keywords (3)： Cell Differentiation , canceration , immune response

Research theme for competitive and other funds (19)：

2024 - 2027 PM2.5による肺がんの発症・悪性化リスクの評価とその作用機序の解明
2023 - 2026 Development of a three-dimensional hard tissue culture system using inorganic polyphosphate and soft-tissue cells.
2023 - 2026 骨芽細胞のI型コラーゲンと基質小胞の分泌経路におけるRabタンパク質の機能解明
2019 - 2024 環境中微粒子の体内、細胞内動態、生体・免疫応答機序の解明と外因的、内因的健康影響決定要因、分子の同定
2020 - 2023 A novel approach for analyzing the three-dimensional dynamics of cell motility by the combined use of scanning ion conductance microscopy and machine-learning

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Papers (53)：

Shiori Ishiyama, Manabu Hayatsu, Taku Toriumi, Hiromasa Tsuda, Keisuke Watanabe, Hirotake Kasai, Satoshi Kishigami, Kazuki Mochizuki, Yoshikazu Mikami. Assessing the combined impact of fatty liver-induced TGF-β1 and LPS-activated macrophages in fibrosis through a novel 3D serial section methodology. Scientific Reports. 2024. 14. 1
Takayuki Asayama, Ayaka Takada, Yoshikazu Mikami, Hirofumi Yamaguchi, Muneaki Tamura, Kunihito Matsumoto, Kiwa Miyake, Yoshiyuki Yonehara, Hiromasa Tsuda. Possible roles of short-chain fatty acids produced by oral bacteria in the development of alveolar osteitis. Journal of Oral Science. 2024. 66. 2. 102-106
Kiwa Miyake, Yoshikazu Mikami, Takayuki Asayama, Taku Toriumi, Keiji Shinozuka, Morio Tonogi, Yoshiyuki Yonehara, Hiromasa Tsuda. Reactive oxygen species generation required for autophagy induction during butyrate- or propionate-induced release of damage-associated molecular patterns from dying gingival epithelial Ca9-22 cells. Journal of Oral Science. 2024. 66. 2. 125-129
Norihisa Uehara, Nobuhide Shibusawa, Yoshikazu Mikami, Yukari Kyumoto-Nakamura, Soichiro Sonoda, Hiroki Kato, Takayoshi Yamaza, Toshio Kukita. Bone metastatic mammary tumor cell-derived extracellular vesicles inhibit osteoblast maturation via JNK signaling. Archives of Biochemistry and Biophysics. 2023. 750. 109821-109821
Keisuke Watanabe, Masao Horie, Manabu Hayatsu, Yoshikazu Mikami, Noboru Sato. Spatiotemporal expression patterns of R-spondins and their receptors, Lgrs, in the developing mouse telencephalon. Gene expression patterns : GEP. 2023. 49. 119333-119333

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Patents (3)：

三次元再構築システムおよび三次元再構築方法
幹細胞の未分化状態を維持する新規方法
アポトーシス抑制剤

Books (3)：

Histology and Cell Biology: An Introduction to Pathology
2022 ISBN:9784524230143
Synergistic effects of BMP-2 and other osteogenic inducers. In: Nohe A, editor. Bone Morphogenetic Proteins: New Research
Nova Science Publishers, Inc. 2011
Autophagy in periodontal disease. In: Gorbunov NV, editor. Autophagy: Principles, Regulation and Roles in Disease
Nova Science Publishers, Inc. Hauppauge 2011

Lectures and oral presentations (18)：

新規3次元解析法を用いた環境中微粒子曝露モデルマウス肺の検討.
(第32回日本臨床環境医学会学術集会分科会シンポジウム 2024)
環境中微粒子曝露マウスにおける肺組織の3次元構造解析.
(第127回日本解剖学会総会・全国学術集会シンポジウム 2022)
Secretory leukocyte peptidase inhibitor(SLPI)による口腔上皮がん由来Ca9-22細胞の移動能・浸潤能亢進機構.
(第 63回歯科基礎医学会学術大会アップデートシンポジウム 2021)
ポリリン酸の石灰化に対する多面的作用機序の解明.
(第124回日本解剖学会総会・全国学術集会 2019)
Secretory leukocyte protease inhibitorによる細胞移動能の制御機構に関する研究.
(第122回日本解剖学会総会・全国学術集会 2017)

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Education (2)：

- 2003 The Graduate University for Advanced Studies, SOKENDAI School of Life Science Department of Genetics
- 1998 Kochi University

Professional career (1)：

博士(理学) (総合研究大学院大学)

Work history (4)：

2016 - 現在新潟大学医学部顕微解剖学分野准教授
2013/10 - Nihon University School of Dentistry
2007/10 - 2013/09/30 Nihon University School of Dentistry
2006/04 - 2007/09 Nihon University School of Dentistry

Awards (2)：

2019 - 日本骨代謝学会 JBMM論文賞 Alkaline phosphatase determines polyphosphate-induced mineralization in a cell-type independent manner
2013 - 日本解剖学会奨励賞骨芽細胞の分化機構の解明と骨再生に関する研究

Association Membership(s) (2)：

日本分子生物学会 , 日本解剖学会

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