Rchr
J-GLOBAL ID:200901008159302120   Update date: Jul. 19, 2024

Motoyama Jun

モトヤマ ジユン | Motoyama Jun
Affiliation and department:
Job title: Professor
Other affiliations (1):
Research field  (2): Neuroscience - general ,  Developmental biology
Research keywords  (5): Neonatal development ,  Neural development ,  developmental biology ,  embryo ,  neural stem cell
Research theme for competitive and other funds  (7):
  • 2020 - 2023 マウス大脳皮質発生過程でのCa2+依存的低濃度Shhシグナル伝達経路の解明
  • 2016 - 2018 Molecular mechanisms of the action of maternal diabetes on the midline determination during mouse brain development
  • 2010 - 2012 Analyses of the role of Shh-expressing cells during mammalian cortical development
  • 2004 - 2005 マウス神経幹細胞の細胞分化・分裂過程における癌抑制遺伝子PTC1の機能の解明
  • 2002 - 2003 多様化したソニックヘッジホッグカスケードによる神経管の発生制御(2)
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Papers (40):
  • Watanabe-Takahashi M, Kumoi K, Yamamoto H, Shimizu E, Motoyama J, Hamabata T, Nishikawa K. Tailored multivalent peptide targeting the B-subunit pentamer of Cholera toxin inhibits its intestinal toxicity by inducing aberrant transport of the toxin in cells. Biochem. Biophys. Res. Commun. 2024. 716. 149991
  • Koji Oishi, Kazunori Nakajima, Jun Motoyama. Activation of Sonic Hedgehog Signaling Promotes Differentiation of Cortical Layer 4 Neurons via Regulation of Their Cell Positioning. Journal of Developmental Biology. 2022. 10. 4. 50-50
  • Putu Adi Andhika Rhaditya, Koji Oishi, Yoshiaki V. Nishimura, Jun Motoyama. [Ca2+] fluctuation mediated by T-type Ca2+ channel is required for the differentiation of cortical neural progenitor cells. Developmental Biology. 2022. 489. 84-97
  • Yuki Murakami, Yukio Imamura, Kuniaki Saito, Daisuke Sakai, Jun Motoyama. Author Correction: Altered kynurenine pathway metabolites in a mouse model of human attention-deficit hyperactivity/autism spectrum disorders: A potential new biological diagnostic marker (Scientific Reports, (2019), 9, 1, (13182), 10.1038/s41598-019-49781-y). Scientific Reports. 2020. 10. 1
  • Yuki Murakami, Yukio Imamura, Kuniaki Saito, Daisuke Sakai, Jun Motoyama. Altered kynurenine pathway metabolites in a mouse model of human attention-deficit hyperactivity/autism spectrum disorders: A potential new biological diagnostic marker. Scientific reports. 2019. 9. 1. 13182
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MISC (13):
  • Toshiaki Okada, Yuki Okumura, Jun Motoyama, Masaharu Ogawa. FGF8 signaling patterns telencephalic midline by regulating putative key factors of midline development. NEUROSCIENCE RESEARCH. 2008. 61. S155-S155
  • Jun Motoyama, Yayoi Shikata, Mitsuhiro Hashimoto, Toshiaki Okada, Masaharu Ogawa. Role of Ptch1 in neural stem cell maintenance during mouse brain development. NEUROSCIENCE RESEARCH. 2008. 61. S156-S156
  • M Ishibashi, H Saitsu, M Komada, M Suzuki, R Nakayama, J Motoyama, K Shiota. Expression of the mouse Fgf15 gene is directly initiated by sonic hedgehog signaling in the diencephalon and midbrain. FASEB JOURNAL. 2006. 20. 5. A878-A878
  • T. Ellis, M. Bourboulas, J. Robson, C. Adolphe, N. Bull, J. Motoyama, P. Bartlett, B. Reynolds, B. Wainwright. Hedgehog Signalling Regulates Both Neurogenesis and Lamination in the Dorsal Forebrain and Midbrain. MOLECULAR BIOLOGY OF THE CELL. 2006. 17
  • E Nieuwenhuis, J Motoyama, Y Yoshikawa, XY Zhang, R Mo, MA Crackower, CC Hui. Alopecia and epidermal hyperplasia in adult male mice lacking normal Patched2 function. DEVELOPMENTAL BIOLOGY. 2004. 271. 2. 625-625
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Professional career (1):
  • 学術 (東京医科歯科大学)
Work history (7):
  • 2024/04 - 現在 Doshisha University Center for Baby Science Director
  • 2012/04 - 現在 Doshisha university Graduate school of brain science Professor
  • 2009/04 - 2012/03 Doshisha university Department of Medical Life Systems, Faculty of Life and Medical Science Professor
  • 2004/04 - 2009/03 RIKEN Brain Science Institute Unit Leader
  • 1999 - 2004 RIKEN Brain Science Institute Senior Scientist
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