J-GLOBAL ID:200901009011108801   Update date: Aug. 28, 2018


ナカシマ ミサコ | NAKASHIMA Misako
Affiliation and department:
Job title: Chief
Research field  (2): Dental engineering/Regenerative dentistry ,  Conservative dentistry
Research keywords  (7): Pulp Capping ,  Pulpotomy ,  Dentinogenesis ,  Tooth Regeneration ,  Gene therapy ,  Bone morphogenetic proteins ,  pulp tissue stem cells
Research theme for competitive and other funds  (6):
  • 1988 - Development of Bioactive Pulp Capping Agents
  • 1988 - Gene therapy for dental pulp by Gdf11
  • 1996 - GliH1, a novel transcription factor which regulate differentiation of odontoblasts
  • 2001 - Caries treatment by biotooth
  • 2003 - Cell fusion of pulp cells with amniom stem cells
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Papers (32):
  • 160. Hayashi Y., Yamamoto K., Yanagiguchi K., Yamada S., Iohara K., Nakashima M. Pulp regeneration using fish collagen as scaffold in dog teeth. 2017 International Association for Dental Research (IADR) /AADR/CADR General Session & Exhibition. San Francisco, USA. 2017
  • 156. Yamada S., Yamamoto K., Matsuura T., Capati MLF., Nakazono A., Nakashima M., Hayashi Y. Fish collagen peptide induces differentiation of human dental pulp stem cells to osteoblasts. International Association for Dental Research (IADR) Pulp Biology and Regeneration Group (PBRG) Symposium 2016. Nagoya. 2016
  • 155. Yamada K., Iwama Y., Iohara K., Nakashima M. hree dimensional modeling and qualitative identification of enamel, periodontal ligament, dentin and newly formed dentin by using commercial dental CBCT and engineering CT images. 2016
  • Iohara K., Nakashima M. The safety and efficacy of autologous transplantation of mobilized dental pulp stem cells (MDPSCs) into the pulpectomized tooth: A preclinical study in dog. International Association for Dental Research (IADR) Pulp Biology and Regeneration Group (PBRG) Symposium 2016. 2016
  • Hayashi Y., Murakami M., Kawamura R., Ishizaka R., Fukuta O., Nakashima M. CXCL14 and MCP1 are potent trophic factors associated with cell migration and angiogenesis leading to higher regenerative potential of dental pulp side population cells. Stem Cell Res Ther. 2015
MISC (28):
Works (1):
  • ex vivo gene therapy using Gdf11 transfected pulp tissue stem cells
    2000 -
Education (1):
  • - 1984 Kyushu University Faculty of Dentistry
Professional career (1):
  • D.D.Sc., PhD (Kyushu University)
Work history (2):
  • 2005 - National Center for Geriatrics and Gerontology, Laboratory of Oral Disease Research, Chief,
  • 1988 - Faculty of Dental Science, Kyushu University, Assistant Professor
Awards (8):
  • 2017/04 - The 2017 Journal of Endodontics Awards Assessment of pulp regeneration induced by stem cell therapy by Magnetic Resonance Imaging (MRI).
  • 2013/05 - International Federation of Endodontic Association The 9th World Endodontic Congress, Best Presentation Award
  • 2005 - 学術賞 Stimulation of reparative dentin formation with ex vivo gene therapy using dental pulp stem cells electro-transfected with Growth/differentiation factor (GDF11). Hum Gene Therapy 15 (11), 1045-1053. 2004.
  • 2004/03 - IADR Travel Award 2004 IADR Pulp Biology Travel Award 2004
  • 2004 - Pulp Biology Travel Award: International Association for dental research
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Association Membership(s) (7):
The Japanese Journal of Conservative Dentistry ,  The Japanese Society for Bone and Mineral Research ,  International Association for Dental Research ,  Japanese Endodontics Association ,  The Molecular Biology Society of JAPAN ,  The Japanese Society for Regenerative Medicine ,  The American Society for Cell Biology
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