Watanabe Masatoshi

ワタナベマサトシ | Watanabe Masatoshi

Affiliation and department：
Job title： Professor
Homepage URL (1)： http://www.medic.mie-u.ac.jp/organization/course/oncopatho/

Research field (3)： Human pathology , Experimental pathology , Applied biofunctional and bioprocess engineering

Research keywords (2)： Nanomedicine , Oncologic Pathology

Research theme for competitive and other funds (30)：

2022 - 2025 Functional analysis of primary cilia in the prostate cancer microenvironment and diagnostic and therapeutic strategies
2022 - 2025 Development of a novel histopathological examination method for castration-resistant prostate cancer focusing on neutral theory of molecular evolution
2019 - 2023 泌尿器腫瘍の診断・治療のための生体膜修飾で拓くナノキャリアのプラットホーム作製
2019 - 2022 Analysis of the effects of adipocytes on prostate cancer cells from the viewpoint of microRNA expression and its clinical application
2019 - 2022 Development of a novel diagnostic method for prostate cancer that targets tumor promoting fibroblast-derived exosomes

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Papers (213)：

Remi Semba, Katsunori Uchida, Yoshihumi Hirokawa, Taizo Shiraishi, Takehisa Onishi, Takeshi Sasaki, Takahiro Inoue, Masatoshi Watanabe, Hiroshi Miyamoto. A simple risk stratification model for prostate cancer using histopathologic findings of radical prostatectomy. American journal of clinical pathology. 2024
Gaku Koizumi, Akinobu Hayashi, Akira Takigawa, Rina Yamada, Taku Murata, Kasumi Shimizu, Masatoshi Watanabe, Naoya Arai. Novel Histopathological Findings of Micro Bone Fragments and Epithelial Response in the Oral Mucosa in Bisphosphonate-Related Osteonecrosis of the Jaw. Journal of Investigative Medicine High Impact Case Reports. 2024. 12
金山和樹, 今井裕, 松田知世, 臼杵恵梨, 広川佳史, 渡邉昌俊. Extrachromosomal DNAは動的調節を介して胃癌での受容体型チロシンキナーゼ発現の腫瘍内不均一性に寄与する(Extrachromosomal DNA contributes to intratumoral heterogeneity of RTKs in gastric cancer through dynamic regulation). 日本癌学会総会記事. 2023. 82回. 1004-1004
Chise Matsuda, Kenichiro Ishii, Yasuhisa Nakagawa, Taku Shirai, Takeshi Sasaki, Yoshifumi S Hirokawa, Kazuhiro Iguchi, Masatoshi Watanabe. Fibroblast-derived exosomal microRNA regulates NKX3-1 expression in androgen-sensitive, androgen receptor-dependent prostate cancer cells. Journal of cellular biochemistry. 2023. 124. 8. 1135-1144
Akiko Eguchi, Motoh Iwasa, Minori Yamada, Yasuyuki Tamai, Ryuta Shigefuku, Hiroshi Hasegawa, Yoshifumi Hirokawa, Akinobu Hayashi, Koji Okuno, Yuki Matsushita, et al. A new detection system for serum fragmented cytokeratin 18 as a biomarker reflecting histologic activities of human nonalcoholic steatohepatitis. Hepatology communications. 2022. 6. 8. 1987-1999

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MISC (96)：

渡邉昌俊. がんの多様性を司るがん間質のバイオロジー新たな診断・治療法の創生につなぐ「はじめに」. 医学のあゆみ. 2019. 270. 12. 1105-1105
石井健一朗, 佐々木豪, 渡邉昌俊, 杉村芳樹. リガンド非依存的なアンドロゲン受容体活性化機構の多様性から考える前立腺癌治療の課題と展望. 泌尿器外科. 2018. 31. 8. 1123-1125
石井健一朗, 臼杵恵梨, 広川佳史, 金山和樹, 松田知世, 内田克典, 杉村芳樹, 渡邉昌俊. 抗線維化薬ピルフェニドンによる癌細胞増殖抑制機構の解析(Pirfenidone, an anti-fibrotic agent, inhibits cell growth of human cancer cells). 日本病理学会会誌. 2018. 107. 1. 299-299
内田克典, 森尾邦正, 西井正彦, 芝原拓児, 大西毅尚, 林昭伸, 広川佳史, 矢花正, 渡邉昌俊. 筋層非浸潤性膀胱癌の再発リスク分類作成の試み. 日本病理学会会誌. 2018. 107. 1. 317-317
内田克典, 森尾邦正, 栗山直久, 臼井正信, 伊佐地秀司, 林昭伸, 広川佳史, 渡邉昌俊. The regression and risk grouping of perihilar cholamgiocarcinoma following neoadjuvant therapy(和訳中). 日本病理学会会誌. 2018. 107. 1. 363-363

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Patents (3)：

前立腺癌、そのリスク又はその初期罹患の判定法
ポリ(ADP-リボース)グリコヒドラーゼによる分解耐性のポリ(エテノADP-リボース)
新規遺伝子多型を用いた前立腺疾患罹患リスクの診断法

Books (3)：

PLEIOTROPIC FUNCTIONS OF MAGNETIC NANOPARTICLES FOR EX VIVO GENE TRANSFER AND CELL TRANSPLANTATION THERAPY/Nano Based Drug Delivery
IAPC Publishing 2015
磁性ナノ粒子を用いた遺伝子導入法/遺伝子治療・診断の最先端技術と新しい医薬品・診断薬の開発
技術情報協会 2014
研修医のための病理マニュアル
診断と治療社 2008

Education (2)：

- 1993 Mie University Graduate School, Division of Medicine
- 1989 Mie University Faculty of Medicine

Professional career (1)：

Doctor (Medical Science) (Mie University)

Work history (10)：

2017/05 - 現在 Mie University Department of Pathologic Oncology, Graduate School of Medicine Professor
2003/04 - 2017/04 Professor, Graduate School of Engineering, Yokohama National University
2011/10 - 2017/03 Yokohama City University
2003/05 - 2017/03 Part-time instructor, School of Medicine, Mie University
2003/11 - 2006/11 Guest professor, Yokohama City University

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Awards (3)：

2015/10/15 - Zoological Society of India The Award of Gold Medal
2001 - 日本病理学会学術研究賞(秋季総会A演説)
2001 - 前立腺がんワークショップ賞(学協会、前立腺がんワークショップ)

Association Membership(s) (6)：

日本臨床細胞学会 , JAPANESE SOCIETY OF LABORATORY MEDICINE , がん疫学・分子疫学研究会 , The International Academy of Pathology Japanese Division , 日本病理学会 , 日本癌学会

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