Rchr
J-GLOBAL ID:200901010698339016
Update date: Aug. 28, 2024
Sugihara Hiroyuki
スギハラ ヒロユキ | Sugihara Hiroyuki
Affiliation and department:
Job title:
Professor
Homepage URL (1):
http://www.shiga-med.ac.jp/~hqpatho1/
Research field (2):
Experimental pathology
, Human pathology
Research keywords (3):
実験病理学
, 分子細胞遺伝学
, 人体病理学
Research theme for competitive and other funds (22):
- 2016 - 2018 Progression risk assessment of non-invasive breast and colorectal carcinomas by gene copy-number profile
- 2013 - 2016 Construction of progression risk assessment system for early gastric carcinoma using genomic copy number profile
- 2009 - 2012 The role of epigenetic regulation of gene expression in progression of undifferentiated-type gastric carcinomas
- 2007 - 2009 Genomic constitutions characteristic of progression-prone differentiated-type early gastric carcinomas
- 2005 - 2006 How gene expression is regulated by genomic dosage and tissue environment in undifferentiated-type gastric carcinomas
- 2004 - 2006 Epigenetic profile of testicular germ cell tumors and its potential for clinical application
- 2004 - 2005 Lineage analyses of gastric carcinomas using chromosomal parts with copy-number changes as genetic markers
- 2003 - 2004 Biological significance of unmethylated DNA in human testicular cancer.
- 2003 - 2004 Roles of X chromosomes as cancer susceptibility gene locus.
- 2003 - 2004 Genome-wide analysis of intratumoral heterogeneity in genomic copy number and expression pattern.
- 2001 - 2002 IDENTIFICATION OF TESTICULAR GERM CELL TUMOR SUSCEPTIBLE GENE ON Xq27 AND INVOLVEMENT OF X INACTIVATION IN TESTICULAR GERM CELL TUMOR TUMORGENESIS
- 2001 - 2002 Temporal analysis of genomic alterations viewed from intratumoral heterogeneity of chromosomal changes
- 1999 - 2000 Chromosomal analysis of diffuse-type gastric carcinoma by CGH and in situ cytogenetics
- 1994 - 1995 A trial of identification of chromosomal aberrations that are important in progression of gastrointestinal tumors by DNA in situ hybridization.
- 1989 - 1991 Development of New Cancer Markers for Diagnosis of Malignancy
- 1989 - 1989 染色体分析とin situ DNA定量からみた近2倍体胃癌細胞の多様性
- 1988 - 1988 胃粘膜上皮におけるself-renewing cellの増殖と分化の動態
- 1987 - 1988 ヒト癌のプロクレッションを左右する分子的機構に関する研究
- 1987 - 1987 胃粘膜上皮におけるself-renewing cellの形態と細胞動態の研究
- 1987 - 1987 ヒト癌のプログレッションを左右する分子機構に関する研究
- 1985 - 1985 癌細胞と間質との相互作用からみたヒト胃癌細胞の浸潤性の研究
- 1980 - Development of signet ring cell carcinoma in the stomach
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Papers (373):
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Yasuhiro Wada, Shigemi Nakajima, Ryoji Kushima, Shizuki Takemura, Naoko Mori, Hiroshi Hasegawa, Takahisa Nakayama, Ken-Ichi Mukaisho, Akiko Yoshida, Shinji Umano, et al. Pyloric, pseudopyloric, and spasmolytic polypeptide-expressing metaplasias in autoimmune gastritis: a case series of 22 Japanese patients. Virchows Archiv : an international journal of pathology. 2021. 479. 1. 169-178
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梅田 朋子, 内藤 弘之, 八木 俊和, 児玉 創太, 長澤 芳信, 辰巳 征浩, 竹林 紀子, 中島 滋美, 馬野 真次, 吉田 章子, et al. 当院における遠隔病理診断ネットワークを利用した乳癌手術. 日本臨床外科学会雑誌. 2021. 82. 5. 1036-1036
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Shoko Murakami, Hiroyuki Tanaka, Takahisa Nakayama, Naoko Taniura, Toru Miyake, Masaji Tani, Ryoji Kushima, Gaku Yamamoto, Hiroyuki Sugihara, Ken-Ichi Mukaisho. Similarities and differences in metabolites of tongue cancer cells among two- and three-dimensional cultures and xenografts. Cancer science. 2021. 112. 2. 918-931
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伊狩 亮, 向所 賢一, 岩佐 卓哉, 仲山 貴永, 影山 進, 杉原 洋行, 河内 明宏. 高純度シリカファイバー担体を用いた膀胱癌と前立腺癌細胞の3次元培養. 日本泌尿器科学会総会. 2020. 108回. 1712-1712
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寺戸 勅雄, 旦部 幸博, 金 哲將, 田中 裕之, 向所 賢一, 杉原 洋行, 井上 寛一. 新規PDK4阻害剤cryptotanshshinoneはグルタミン代謝を阻害してKRAS活性化癌を抑制する. 日本癌学会総会記事. 2020. 79回. PJ17-1
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MISC (438):
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大村寧, 高木彩乃, 小杉和希, 鍬田菜摘, 西村公宏, 石垣宏仁, 杉原洋行. 劇症1型糖尿病様の経過で突然死し,病理解剖を施行した一症例. 糖尿病(Web). 2023. 66. 4
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神山創路, 伊藤哲郎, 高木彩乃, 南部卓三, 杉原洋行, おの田汐莉, 石垣宏仁. A case of fatal hyperpotassemia resulting from tumor lysis of latent urinary bladder cancer and repeated circulatory insufficiency. 公立甲賀病院紀要. 2020. 23
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福田 昌英, 石垣 宏仁, 松原 亜季子, 森谷 鈴子, 向所 賢一, 杉原 洋行, 伊藤 靖, 小笠原 一誠, 村上 和成, 九嶋 亮治. プロトンポンプ阻害薬内服患者における胃底腺ポリープの組織学的特徴とポリープ増大因子の検討. 日本病理学会会誌. 2019. 108. 1. 488-488
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加藤寿一, 馬場正道, 北村憲一, 平本秀一, 増山 守, 加藤元一, 杉原洋行, 森谷鈴子, 九嶋亮治. Mott cellの目立つ低悪性度B細胞リンパ腫の1例。. 診断病理. 2019. 36. 1. 52-56
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向所賢一, 金井俊平, 服部隆則, 杉原洋行. バレット腺癌の発生機序 : III. 食道癌の生物学:食道癌(第2版)ー基礎・臨床研究の進歩. 日本臨床:増刊. 2018. 76. 8. 70-75
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Books (13):
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ゲノムレベルと発現レベルの系譜解析-早期癌の進展リスク予測を例として (In: 組織細胞化学 2014)
日本組織細胞化学会 2014
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Development of Columnar-Lined Esophagus with or without Goblet Cells in Rat Duodenogastroesophageal Reflux Models Through Gut Regenerative Cell Lineage (GRCL) 「Animal Models in Cancer Research and Human Disease: Applications, Outcomes and Controvers・・・
Nova Science Publishers 2013
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Development of Columnar-Lined Esophagus with or without Goblet Cells in Rat Duodenogastroesophageal Reflux Models Through Gut Regenerative Cell Lineage (GRCL) 「Animal Models in Cancer Research and Human Disease: Applications, Outcomes and Controvers・・・
Nova Science Publishers 2013
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(1)食道;第1項 誘発モデル:第1節 消化管 : 第3章 消化器系「がん ー 疾患モデルの作製と利用 」
エル・アイ・シー 2012
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Integrin and E-Cadherin Expression Alterations as a Possible Reason of Undifferentiated-Type Gastric Carcinoma Diversity:「Gastric Carcinoma- Molecular Aspects and Current Advances」
InTech 2011
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Lectures and oral presentations (2):
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さざなみ病理ネットによる術中迅速診断の現状と課題
(第6回地域ICT利活用連携事業シンポジウム 2017)
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がんをどう理解し説明するか: 発がんメカニズムから考える
(京都消化器医会学術講演会 2015)
Education (4):
- - 1984 Kyoto Prefectural University of Medicine
- - 1984 Kyoto Prefectural University of Medicine Graduate School, Division of Medicine
- - 1980 Kyoto Prefectural University of Medicine
- - 1980 Kyoto Prefectural University of Medicine Faculty of Medicine
Professional career (1):
Work history (7):
- 1995 - 2009 Shiga University of Medical Science
- 1990 - 1995 Kyoto Prefectural University of Medicine
- 1990 - 1995 Kyoto Prefectural University of Medicine, Instructor
- 1989 - 1990 Kyoto Prefectural University of Medicine
- 1989 - 1990 Kyoto Prefectural University of Medicine, Research Assistant
- 1984 - 1989 Fukui Medical University
- 1984 - 1989 Fukui Medical School, Research Assistant
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Committee career (6):
Association Membership(s) (5):
組織細胞化学会
, サイトメトリー学会
, 日本胃癌学会
, 病理学会
, 癌学会
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